Zobrazeno 1 - 10
of 273
pro vyhledávání: '"P N, Jones"'
Autor:
Devin N. Jones, Ben C. Augustine, Patrick Hutchins, James M. Birch, Kevan M. Yamahara, Scott Jensen, Rodney Richardson, Regina Trott, James R. Campbell, Elliott Barnhart, Adam J. Sepulveda
Publikováno v:
Metabarcoding and Metagenomics, Vol 8, Iss , Pp 235-257 (2024)
Unprecedented rates of biodiversity loss and ecosystem function necessitate the use of rapid, efficacious, and cost-effective biomonitoring tools. The combination of autonomous samplers and high throughput sequencing (i.e., “metabarcoding”) of en
Externí odkaz:
https://doaj.org/article/0d471e82cfea49ffadb988a05d4810c8
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Neuroinflammation is characterized by the elevation of cytokines and adenosine triphosphate (ATP), which in turn activates microglia. These immunoregulatory molecules typically form gradients in vivo, which significantly influence microglial
Externí odkaz:
https://doaj.org/article/7a2b3edf2a5a4c129d06b18af0dec757
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cancer cells recruit neutrophils from the bloodstream into the tumor tissue, where these immune cells promote the progression of numerous solid tumors. Studies in mice suggest that blocking neutrophil recruitment to tumors by inhibition of n
Externí odkaz:
https://doaj.org/article/6b19897f60404810a1f315a9ef3e98a3
Publikováno v:
Frontiers in Social Psychology, Vol 2 (2024)
IntroductionDemographic changes occurring throughout the world, as well as different forms of climate and social movements, are examples of the constant cultural change people experience. Many of these changes reflect broad political and existential
Externí odkaz:
https://doaj.org/article/aa113720369b4b009f9f507668b1ce50
Publikováno v:
The Cryosphere, Vol 18, Pp 2335-2356 (2024)
In dry southwestern South Tyrol, Italy, rock glaciers are dominant landforms of the high-mountain cryosphere. Their spatial distribution and degree of activity hold critical information on the current state of discontinuous permafrost and consequentl
Externí odkaz:
https://doaj.org/article/580a52ec111e4abb9e2a64fb0885f8f1
Autor:
Yoshiko Sakuma, Marie L. E. Miller, Daphne S. Babalis, Alex Baker, Meena Reddi, Aisha Anjum, Jane Bruton, Kathryn N Jones, Umm Zeinab Mulla, Henock Taddese
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background It is crucial to include a wide range of the population in clinical trials for the outcome to be applicable in real-world settings. Existing literature indicates that under-served groups, including disabled people, have been exclu
Externí odkaz:
https://doaj.org/article/388aee8fa91249fb955788873433063f
Autor:
Stephanie P. Goldstein, Kevin M. Mwenda, Adam W. Hoover, Olivia Shenkle, Richard N. Jones, John Graham Thomas
Publikováno v:
Digital Health, Vol 10 (2024)
Objective Lifestyle intervention can produce clinically significant weight loss and reduced disease risk/severity for many individuals with overweight/obesity. Dietary lapses, instances of non-adherence to the recommended dietary goal(s) in lifestyle
Externí odkaz:
https://doaj.org/article/f360f785d23644d484c7f9c928343cc7
Autor:
Elizabeth L. Hardaker, Emilio Sanseviero, Ankur Karmokar, Devon Taylor, Marta Milo, Chrysis Michaloglou, Adina Hughes, Mimi Mai, Matthew King, Anisha Solanki, Lukasz Magiera, Ricardo Miragaia, Gozde Kar, Nathan Standifer, Michael Surace, Shaan Gill, Alison Peter, Sara Talbot, Sehmus Tohumeken, Henderson Fryer, Ali Mostafa, Kathy Mulgrew, Carolyn Lam, Scott Hoffmann, Daniel Sutton, Larissa Carnevalli, Fernando J. Calero-Nieto, Gemma N. Jones, Andrew J. Pierce, Zena Wilson, David Campbell, Lynet Nyoni, Carla P. Martins, Tamara Baker, Gilberto Serrano de Almeida, Zainab Ramlaoui, Abdel Bidar, Benjamin Phillips, Joseph Boland, Sonia Iyer, J. Carl Barrett, Arsene-Bienvenu Loembé, Serge Y. Fuchs, Umamaheswar Duvvuri, Pei-Jen Lou, Melonie A. Nance, Carlos Alberto Gomez Roca, Elaine Cadogan, Susan E. Critichlow, Steven Fawell, Mark Cobbold, Emma Dean, Viia Valge-Archer, Alan Lau, Dmitry I. Gabrilovich, Simon T. Barry
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The Ataxia telangiectasia and Rad3-related (ATR) inhibitor ceralasertib in combination with the PD-L1 antibody durvalumab demonstrated encouraging clinical benefit in melanoma and lung cancer patients who progressed on immunotherapy. Here we
Externí odkaz:
https://doaj.org/article/189773f2417346dcbdf8b6281d57effa
Autor:
Jake W Anderson, David Vaisar, David N Jones, Laurel M Pegram, Guy P Vigers, Huifen Chen, John G Moffat, Natalie G Ahn
Publikováno v:
eLife, Vol 12 (2024)
Activation of the extracellular signal-regulated kinase-2 (ERK2) by phosphorylation has been shown to involve changes in protein dynamics, as determined by hydrogen-deuterium exchange mass spectrometry (HDX-MS) and NMR relaxation dispersion measureme
Externí odkaz:
https://doaj.org/article/089ca721611842539172a5e7837a22f2
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 23, Pp 1095-1115 (2023)
There is a clear need to improve and update landslide susceptibility models across the Philippines. This is challenging, as landslides in this region are frequently triggered by temporally and spatially disparate typhoon events, and it remains unclea
Externí odkaz:
https://doaj.org/article/b1257e6f5b204b03b2b3d1c5a6c84742