Zobrazeno 1 - 10
of 137
pro vyhledávání: '"P N, Chan"'
Autor:
Weiwei Zeng, Tanya T. W. Chu, Benny S. P. Fok, Walter K. K. Ho, Juliana C. N. Chan, Brian Tomlinson
Publikováno v:
Dose-Response, Vol 22 (2024)
Objectives: The purpose of this study was to examine the effect of hawthorn extract drink in mildly hypertensive and/or hyperlipidaemic Chinese patients. Methods: We performed a randomized double-blind placebo-controlled crossover study. Subjects who
Externí odkaz:
https://doaj.org/article/6e31dfd7ab694550a4b3f67db264b51b
Autor:
Ke Wang, Mai Shi, Andrea O. Y. Luk, Alice P. S. Kong, Ronald C. W. Ma, Changhong Li, Li Chen, Elaine Chow, Juliana C. N. Chan
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Glucokinase (GK) plays a key role in glucose metabolism. In the liver, GK is regulated by GK regulatory protein (GKRP) with nuclear sequestration at low plasma glucose level. Some GK activators (GKAs) disrupt GK-GKRP interaction w
Externí odkaz:
https://doaj.org/article/ab74b99469fc4c329a175d4f6db6e49d
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-13 (2024)
Abstract Background Since the last guidance was published by the Canadian Thoracic Society, there have been several advances in the clinical management of severe asthma. To gain a better understanding of the current standards of care and treatment pa
Externí odkaz:
https://doaj.org/article/b82e734f3de647ed9fd705444bdf4859
Autor:
Mary Froehlich, MD, Elizabeth M. Sodomin, MD, Taylor Fontenot, MD, Noama Iftekhar, MD, Christian N. Chan, MD, Annabel Barber, MD
Publikováno v:
Surgery Open Science, Vol 18, Iss , Pp 103-106 (2024)
Background: The incidence of Mirizzi Syndrome ranges from 0.05 to 5.7 % of patients who undergo cholecystectomy. The purpose of this study is to examine the preoperative workup and postoperative outcomes for patients diagnosed with Mirizzi Syndrome.
Externí odkaz:
https://doaj.org/article/d414cf95bc8b486fa4353a316229dd65
Autor:
Meilin Xue, Lei Dong, Honghai Zhang, Yangchan Li, Kangqiang Qiu, Zhicong Zhao, Min Gao, Li Han, Anthony K. N. Chan, Wei Li, Keith Leung, Kitty Wang, Sheela Pangeni Pokharel, Ying Qing, Wei Liu, Xueer Wang, Lili Ren, Hongjie Bi, Lu Yang, Chao Shen, Zhenhua Chen, Laleh Melstrom, Hongzhi Li, Nikolai Timchenko, Xiaolan Deng, Wendong Huang, Steven T. Rosen, Jingyan Tian, Lin Xu, Jiajie Diao, Chun-Wei Chen, Jianjun Chen, Baiyong Shen, Hao Chen, Rui Su
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-24 (2024)
Abstract Background While liver cancer stem cells (CSCs) play a crucial role in hepatocellular carcinoma (HCC) initiation, progression, recurrence, and treatment resistance, the mechanism underlying liver CSC self-renewal remains elusive. We aim to c
Externí odkaz:
https://doaj.org/article/b8cac747695b48e59f1516ff7bd9a5a7
Autor:
Juliana N. M. Lui, Eric S. H. Lau, Aimin Yang, Hongjiang Wu, Amy Fu, Vanessa Lau, Kitman Loo, Theresa Yeung, Rebecca Yue, Ronald C. W. Ma, Alice P. S. Kong, Risa Ozaki, Andrea O. Y. Luk, Elaine Y. K. Chow, Juliana C. N. Chan
Publikováno v:
Journal of Diabetes, Vol 16, Iss 6, Pp n/a-n/a (2024)
Abstract Background Patients with type 2 diabetes (T2D) are at high risk of developing multiple complications, affecting their health‐related quality of life (HRQoL). Existing studies only considered impact of complication on HRQoL in the year of o
Externí odkaz:
https://doaj.org/article/ec52cf3431f449478f0f67ef06ebbcae
Autor:
Elaine Cheung, Maggie Wang, Juliana C N Chan, Samuel YS Wong, Risa Ozaki, Eric KP Lee, Ronald Ching Wan Ma, Alice Pik Shan Kong, Baoqi Fan, Eric S H Lau, Elaine Chow, Chun Kwan O, Ying Nan Fan, Cadmon Lim, Sandra T F Tsoi, Raymond Wan, Wai Yin Lai, Emily WM Poon, Jane Ho, Cherry Cheuk Yee Ho, Chloe Fung, Andrea Luk
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 3 (2024)
Introduction We designed and implemented a patient-centered, data-driven, holistic care model with evaluation of its impacts on clinical outcomes in patients with young-onset type 2 diabetes (T2D) for which there is a lack of evidence-based practice
Externí odkaz:
https://doaj.org/article/11f750ed53064e6cb4f31a23a77dddae
Publikováno v:
European Psychiatry, Vol 67, Pp S333-S334 (2024)
Introduction The negative impact of adverse childhood experiences (ACEs) on mental health has been well documented. While most of the evidence comes from samples of adolescents and young adults, few studies have investigated whether ACEs contribute t
Externí odkaz:
https://doaj.org/article/37a82b931a754da3906ca1c597de7d3e
Autor:
Mai Shi, Aimin Yang, Eric S H Lau, Andrea O Y Luk, Ronald C W Ma, Alice P S Kong, Raymond S M Wong, Jones C M Chan, Juliana C N Chan, Elaine Chow
Publikováno v:
PLoS Medicine, Vol 21, Iss 4, p e1004369 (2024)
BackgroundOlder adults with diabetes are at high risk of severe hypoglycemia (SH). Many machine-learning (ML) models predict short-term hypoglycemia are not specific for older adults and show poor precision-recall. We aimed to develop a multidimensio
Externí odkaz:
https://doaj.org/article/2cc1b2e4f382441f9d1fce2c533d5ec8
Publikováno v:
Biology, Vol 13, Iss 7, p 498 (2024)
Exploring the intricate crosstalk between dietary prebiotics and the specific intestinal microbiome (SIM) is intriguing in explaining the mechanisms of current successful dietary interventions, including the Mediterranean diet and high-fiber diet. Th
Externí odkaz:
https://doaj.org/article/7b01eb6a1e364d989ad20d7aa8ddb5dc