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Association of candidate pharmacogenetic markers with platinum-induced ototoxicity: PanCareLIFE dataset

Autor: Thorsten Langer, Eva Clemens, Linda Broer, Lara Maier, André G. Uitterlinden, Andrica C.H. de Vries, Martine van Grotel, Saskia F.M. Pluijm, Harald Binder, Benjamin Mayer, Annika von dem Knesebeck, Julianne Byrne, Eline van Dulmen-den Broeder, Marco Crocco, Desiree Grabow, Peter Kaatsch, Melanie Kaiser, Claudia Spix, Line Kenborg, Jeanette F. Winther, Catherine Rechnitzer, Henrik Hasle, Tomas Kepak, Anne-Lotte F. van der Kooi, Leontien C. Kremer, Jarmila Kruseova, Stefan Bielack, Benjamin Sorg, Stefanie Hecker-Nolting, Claudia E. Kuehni, Marc Ansari, Martin Kompis, Heleen J. van der Pal, Ross Parfitt, Dirk Deuster, Peter Matulat, Amelie Tillmanns, Wim J.E. Tissing, Jörn D. Beck, Susanne Elsner, Antoinette am Zehnhoff-Dinnesen, Marry M. van den Heuvel-Eibrink, Oliver Zolk

Publikováno v: Data in Brief, Vol 32, Iss , Pp 106227- (2020)

Genetic association studies suggest a genetic predisposition for cisplatin-induced ototoxicity. Among other candidate genes, thiopurine methyltransferase (TPMT) is considered a critical gene for susceptibility to cisplatin-induced hearing loss in a p

Externí odkaz: https://doaj.org/article/35d55296833a41b88236d9c151db2d3e

TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study

Autor: Wim J. E. Tissing, J Kruseova, A E Hoetink, G Calaminus, R Haupt, I K Domingo, E van Dulmen-den Broeder, Amit P. Bhavsar, J Byrne, H Hasle, C Spix, S Elsner, A P Nagtegaal, L Kenborg, J Gebauer, O Zolk, S M F Pluijm, A J M Meijer, H Binder, R A Ozinga, C Rechnitzer, S J C M M Neggers, M L Garrè, P Matulat, D Deuster, T Langer, Britt I. Drögemöller, H. J. H. van der Pal, D Grabow, Leontien C. M. Kremer, Galen E.B. Wright, E Clemens, A.L.F. van der Kooi, M Kaiser, Bruce Carleton, F A Diepstraten, J F Winther, C Blattmann, L Broer, M van Grotel, R Parfitt, A G Am Zehnhoff-Dinnesen, K Kepakova, H Lackner, M M van den Heuvel-Eibrink, Shahrad Rod Rassekh, T Kepak, A. C. H. de Vries, Beth Brooks, André G. Uitterlinden, C. E. Kuehni, A Tillmanns, Wilbert P. Vermeij, Colin J. D. Ross, P Kaatsch

Publikováno v: 37. Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP); 20210917-20210918; sine loco [digital]; DOCP15 /20211028/
The PanCareLIFE Consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, no. 1, 64 . https://doi.org/10.1038/s41698-021-00178-z
Meijer, A J M, Diepstraten, F A, Langer, T, Broer, L, Domingo, I K, Clemens, E, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Vermeij, W P, Ozinga, R A, Binder, H, Byrne, J, van Dulmen-den Broeder, E, Garrè, M L, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, Kepakova, K, Tissing, W J E, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Pluijm, S M F, Kuehni, C E, van der Pal, H J H, Parfitt, R, Spix, C, Tillmanns, A, Deuster, D, Matulat, P, Calaminus, G, Hoetink, A E, Elsner, S, Gebauer, J, Haupt, R, Lackner, H, Blattmann, C, Neggers, S J C M M, Rassekh, S R, Wright, G E B, Brooks, B, Nagtegaal, A P, Drögemöller, B I, Ross, C J D, The PanCareLIFE consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, no. 1, 64 . https://doi.org/10.1038/s41698-021-00178-z
Meijer, A J M, Diepstraten, F A, Langer, T, Broer, L, Domingo, I K, Clemens, E, Uitterlinden, A G, de Vries, A C H, van Grotel, M, Vermeij, W P, Ozinga, R A, Binder, H, Byrne, J, van Dulmen-den Broeder, E, Garrè, M L, Grabow, D, Kaatsch, P, Kaiser, M, Kenborg, L, Winther, J F, Rechnitzer, C, Hasle, H, Kepak, T, Kepakova, K, Tissing, W J E, van der Kooi, A L F, Kremer, L C M, Kruseova, J, Pluijm, S M F, Kuehni, C E, van der Pal, H J H, Parfitt, R, Spix, C, Tillmanns, A, Deuster, D, Matulat, P, Calaminus, G, Hoetink, A E, Elsner, S, Gebauer, J, Haupt, R, Lackner, H, Blattmann, C, Neggers, S J C M M, Rassekh, S R, Wright, G E B, Brooks, B, Nagtegaal, A P, Drögemöller, B I, Ross, C J D, the PanCareLIFE Consortium & and the CPNDS Consortium 2021, ' TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study ', npj Precision Oncology, vol. 5, 64 . https://doi.org/10.1038/s41698-021-00178-z
npj Precision Oncology, 5(1):64. Springer Nature
Meijer, A J M; Diepstraten, F A; Langer, T; Broer, L; Domingo, I K; Clemens, E; Uitterlinden, A G; de Vries, A C H; van Grotel, M; Vermeij, W P; Ozinga, R A; Binder, H; Byrne, J; van Dulmen-den Broeder, E; Garrè, M L; Grabow, D; Kaatsch, P; Kaiser, M; Kenborg, L; Winther, J F; ... (2021). TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study. NPJ precision oncology, 5(1), p. 64. Springer Nature 10.1038/s41698-021-00178-z
NPJ Precision Oncology
NPJ precision oncology, 5(1):64, 1-8. Nature Research
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)

Background: Ototoxicity (hearing loss, tinnitus and/or vertigo) is a serious adverse event of cisplatin treatment in children with cancer. The heterogeneity in ototoxicity occurrence after similar treatment suggests a role for genetic susceptibility.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b1abb74a67b5c6ca531ead07151865
http://www.egms.de/en/meetings/dgpp2021/21dgpp30.shtml

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