Zobrazeno 1 - 10
of 1 237
pro vyhledávání: '"P M, Yen"'
Autor:
Madhulika Tripathi, Karine Gauthier, Reddemma Sandireddy, Jin Zhou, Priyanka Guptta, Suganya Sakthivel, Wei Wen Teo, Yadanar Than Naing, Kabilesh Arul, Keziah Tikno, Sung-Hee Park, Yajun Wu, Lijin Wang, Boon-Huat Bay, Lei Sun, Vincent Giguere, Pierce K.H. Chow, Sujoy Ghosh, Donald P. McDonnell, Paul M. Yen, Brijesh K. Singh
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101997- (2024)
Objective: Currently, little is known about the mechanism(s) regulating global and specific protein translation during metabolic dysfunction-associated steatohepatitis (MASH; previously known as non-alcoholic steatohepatitis, NASH). Methods: Unbiased
Externí odkaz:
https://doaj.org/article/17f87e3dbde54cfa8579d8857c0fe2d1
Autor:
Douglas D. Reh, Kristopher Lay, Greg Davis, Marc G. Dubin, David M. Yen, Ellen M. O'Malley, Michael Sillers
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 9, Iss 3, Pp n/a-n/a (2024)
Abstract Objective To assess long‐term safety and effectiveness of a multipoint, impedance‐controlled, RF ablation device for treatment of chronic rhinitis through 12‐month follow‐up. Methods A prospective, multicenter study. Bilateral poster
Externí odkaz:
https://doaj.org/article/efa5d3a013794786af1b6c4717ea0c08
Autor:
Douglas D. Reh, Kristopher Lay, Greg Davis, Marc G. Dubin, David M. Yen, Ellen M. O'Malley, Michael Sillers
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 8, Iss 2, Pp 367-372 (2023)
Abstract Objective Safety and efficacy of the NEUROMARK® system for treating chronic rhinitis. Methods A prospective, single‐arm, multicenter study was performed on adults with chronic rhinitis who underwent radiofrequency ablation to the posterio
Externí odkaz:
https://doaj.org/article/d1e090eda6e24004906ea5226fb7e886
Akademický článek
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Autor:
Smarajit Chakraborty, Wee Kiat Ong, Winifred W. Y. Yau, Zhihong Zhou, K. N. Bhanu Prakash, Sue-Anne Toh, Weiping Han, Paul M. Yen, Shigeki Sugii
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)
Abstract Background Effective stem cell therapy is dependent on the stem cell quality that is determined by their differentiation potential, impairment of which leads to poor engraftment and survival into the target cells. However, limitations in our
Externí odkaz:
https://doaj.org/article/ca6b50ac2ba14c5889a290b4470f21f9
Autor:
Jinrui Dong, Sivakumar Viswanathan, Eleonora Adami, Brijesh K. Singh, Sonia P. Chothani, Benjamin Ng, Wei Wen Lim, Jin Zhou, Madhulika Tripathi, Nicole S. J. Ko, Shamini G. Shekeran, Jessie Tan, Sze Yun Lim, Mao Wang, Pei Min Lio, Paul M. Yen, Sebastian Schafer, Stuart A. Cook, Anissa A. Widjaja
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
IL11 contributes to the development of non-alcoholic steatohepatitis (NASH) through incompletely understood mechanisms. Here, the authors report that lipotoxicity-driven autocrine IL11 activity underlies hepatocyte metabolic dysfunction and death via
Externí odkaz:
https://doaj.org/article/ce2b5ee017d5453ea86274564e8eb24f
Autor:
Eveline Bruinstroop, Jin Zhou, Madhulika Tripathi, Winifred W. Yau, Anita Boelen, Brijesh Kumar Singh, Paul M. Yen
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101266- (2021)
Objective: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T4) have a higher incidence
Externí odkaz:
https://doaj.org/article/d879531f2fef46d28ca34500556eedee
Autor:
Sangam Rajak, Sherwin Xie, Archana Tewari, Sana Raza, Yajun Wu, Boon-Huat Bay, Paul M. Yen, Rohit A. Sinha
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101286- (2021)
Objective: Crinophagy is a secretory granule-specific autophagic process that regulates hormone content and secretion in endocrine cells. However, despite being one of the earliest described autophagic processes, its mechanism of action and regulatio
Externí odkaz:
https://doaj.org/article/9d5b34b8cf7b486dbe260df9e11bf0cd
Conference
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Autor:
Sangam Rajak, Liliana F. Iannucci, Jin Zhou, B. Anjum, Nelson George, Brijesh K. Singh, Sujoy Ghosh, Paul M. Yen, Rohit A. Sinha
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The hepatic mevalonate (MVA) pathway, responsible for cholesterol biosynthesis, is a therapeutically important metabolic pathway in clinical medicine. Using an unbiased transcriptomics approach, we uncover a novel role of Unc-51 like autophagy activa
Externí odkaz:
https://doaj.org/article/78ab8411a3ac4d1e97a6b88b8b186848