Zobrazeno 1 - 8
of 8
pro vyhledávání: '"P M, Terheggen"'
Autor:
F A, Blommaert, C, Michael, P M, Terheggen, F M, Muggia, V, Kortes, J H, Schornagel, A A, Hart, L, den Engelse
Publikováno v:
Cancer research. 53(23)
Twenty-six patients with a variety of tumor types were treated according to a phase 1 experimental treatment protocol consisting of repetitive cycles of cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) (carboplatin, 200-480 mg/m2) at day 1 and
Publikováno v:
Cancer research. 50(12)
The relationship between cell killing and the binding of the anticancer drug cis-diamminedichloroplatinum(II) (cis-DDP) to DNA was studied in six mammalian cell lines. Two of the human cell lines (COV413B) were of the same origin, comprising one sens
Publikováno v:
The Journal of Immunology. 134:1292-1299
The involvement of mast cells in anti-tumor resistance was studied by employing 2 strains of mast cell deficient but otherwise immunocompetent mice on a C57BL/6 (H-2b) background (W/Wv and Sl/Sld) and their respective normal +/+ littermate controls.
Autor:
L, Den Engelse, J, Bax, P M, Terheggen, F J, Van Schooten, J, Van Benthem, C P, Wild, E, Scherer
Publikováno v:
Annali dell'Istituto superiore di sanita. 25(1)
Antibodies recognizing specific DNA modifications allow the immunocytochemical visualization and quantification of these modifications at the level of the individual cell. Thus, the formation and repair of DNA adducts induced by chemical mutagens and
Publikováno v:
Cancer research. 48(19)
The formation and stability of interaction products between the anti-cancer drug cis-diamminedichloroplatinum(II) (cis-DDP) and DNA were studied in buccal epithelial and urinary cells from ten cancer patients who received cis-DDP-based therapy. Bucca
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 134(2)
The involvement of mast cells in anti-tumor resistance was studied by employing 2 strains of mast cell deficient but otherwise immunocompetent mice on a C57BL/6 (H-2b) background (W/Wv and Sl/Sld) and their respective normal +/+ littermate controls.
Publikováno v:
Cancer research. 47(24 Pt 1)
Calf thymus DNA was modified in vitro by cis-diamminedichloroplatinum(II) (cisDDP), complexed with methylated bovine serum albumin and used to immunize rabbits. The anti-cisDDP-DNA antiserum obtained was applied in a double peroxidase-antiperoxidase
Publikováno v:
IARC scientific publications. (89)
The immunocytochemical staining of carcinogen-DNA adducts by a double peroxidase-anti-peroxidase (PAP) method is critically described. It is a powerful new tool for the investigation of the initial processes of chemical carcinogenesis--such as metabo