Zobrazeno 1 - 10
of 22
pro vyhledávání: '"P M, Plotsky"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:2556-2563
Age-related changes in glucocorticoid negative feedback inhibition of hypothalamic CRF and pituitary ACTH are observed in rodents. Attempts to study similar effects in humans have produced mixed results due in part to the difficulty in matching older
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4b1de763f7a717e1d8e5a16b3f37b4
https://doi.org/10.1210/jcem.85.7.6696
https://doi.org/10.1210/jcem.85.7.6696
Publikováno v:
Endocrinology. 136:1864-1868
Mechanical compression of the pituitary stalk with the help of a blunt stereotaxic knife results in posterior pituitary denervation (PPD) and sprouting proximal to the injury, leading to formation of an ectopic neurohypophysis in the stalk. This prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c486725a0e7be34103717baf434724e
https://doi.org/10.1210/endo.136.5.7720631
https://doi.org/10.1210/endo.136.5.7720631
Autor:
P. M. Plotsky
Publikováno v:
Endocrinology. 130:1931-1941
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fc658537fd2003e663ba48b7369aacd
https://doi.org/10.1210/en.130.4.1931
https://doi.org/10.1210/en.130.4.1931
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
Corticotropin-releasing factor 1 (CRF(1)) receptor antagonists may represent a novel group of drugs for the pharmacotherapy of depression and/or anxiety disorders. We have investigated the behavioral, endocrine, and neurochemical effects of chronic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d0f9e7add7a288585e52b8594e81abd
https://pubmed.ncbi.nlm.nih.gov/10900236
https://pubmed.ncbi.nlm.nih.gov/10900236
Publikováno v:
Progress in brain research. 122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce5a3452c1a810c259d498d02cbfa148
https://pubmed.ncbi.nlm.nih.gov/10737052
https://pubmed.ncbi.nlm.nih.gov/10737052
Publikováno v:
Journal of neuroendocrinology. 12(1)
Postnatal rearing conditions influence the development of hypothalamic-pituitary-adrenal (HPA) responses to stress in the rat. Thus, postnatal handling dampens HPA responsivity to stress, while prolonged periods of maternal separation have the opposi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b24e17416653585d508182a89baed8d7
https://pubmed.ncbi.nlm.nih.gov/10692138
https://pubmed.ncbi.nlm.nih.gov/10692138
Publikováno v:
The Journal of comparative neurology. 408(3)
Two different corticotropin-releasing factor (CRF) receptors, CRF1 and CRF2, have been identified in rat and human brain. Although the two receptor subtypes show a markedly different distribution in the rat brain, their distribution in the primate br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f14e8a64d28a9b73cedee3cb18d240e
https://pubmed.ncbi.nlm.nih.gov/10340512
https://pubmed.ncbi.nlm.nih.gov/10340512
Publikováno v:
The Psychiatric clinics of North America. 21(2)
Among the more consistent observations in patients with major depression is dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis presenting as elevation of basal cortisol, dexamethasone-mediated negative feedback resistance, increased cerebro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3aa29665135ff63cc537d14205aea2c3
https://pubmed.ncbi.nlm.nih.gov/9670227
https://pubmed.ncbi.nlm.nih.gov/9670227
Autor:
M J, Meaney, J, Diorio, D, Francis, J, Widdowson, P, LaPlante, C, Caldji, S, Sharma, J R, Seckl, P M, Plotsky
Publikováno v:
Developmental neuroscience. 18(1-2)
The adrenal glucocorticoids and catecholamines comprise a frontline of defense for mammalian species under conditions which threaten homeostasis (conditions commonly referred to as stress). Glucocorticoids represent the end product of the hypothalami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b77f45ef6c6968af89d61f5bb52f3a0
https://pubmed.ncbi.nlm.nih.gov/8840086
https://pubmed.ncbi.nlm.nih.gov/8840086
Publikováno v:
Endocrinology. 134(3)
Aging is frequently associated with changes in physiological and cognitive processes. Among these changes is a distinct dysregulation of the hypothalamic-pituitary-adrenal axis. In the current experiments, aspects of hypothalamic-pituitary-adrenal ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5784dc1ebb52275db63a3c83d966d4a8
https://pubmed.ncbi.nlm.nih.gov/8119195
https://pubmed.ncbi.nlm.nih.gov/8119195