Zobrazeno 1 - 10
of 170
pro vyhledávání: '"P M, O'Neill"'
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1914-1925 (2024)
To improve the translation of preclinical cancer research data to successful clinical effect, there is an increasing focus on the use of primary patient‐derived cancer cells with limited growth in culture to reduce genetic and phenotype drift. Howe
Externí odkaz:
https://doaj.org/article/d97b5a43def148049640c55602ec9a9d
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Winter annual crops are sown in late summer or autumn and require chilling to promote flowering the following spring. Floral initiation begins in autumn and winter, and in winter oilseed rape (OSR), continued chilling during flower development is nec
Externí odkaz:
https://doaj.org/article/59924052b7b34ad5bcba0e612f0bd815
Autor:
Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M. O’Neill, Koji Yamanaka, S. Samar Hasnain
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) selectively affects motor neurons. SOD1 is the first causative gene to be identified for ALS and accounts for at least 20% of the familial (fALS) and up to 4% of sporadic (sALS) cases globally with some ge
Externí odkaz:
https://doaj.org/article/5cce70c881dc4718bdc19c5c4fdd5fa7
Publikováno v:
PeerJ, Vol 12, p e17902 (2024)
Background Managed populations of the alfalfa leafcutting bee (ALCB), Megachile rotundata (F.), are often not sustainable. In addition to numerous mortality factors that contribute to this, the dense bee populations used to maximize alfalfa pollinati
Externí odkaz:
https://doaj.org/article/40b9976a05e5454ba093e05f1cbdf3f1
Autor:
Kate M. O’Neill, Erin D. Anderson, Shoutik Mukherjee, Srinivasa Gandu, Sara A. McEwan, Anton Omelchenko, Ana R. Rodriguez, Wolfgang Losert, David F. Meaney, Behtash Babadi, Bonnie L. Firestein
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-26 (2023)
Abstract Plasticity and homeostatic mechanisms allow neural networks to maintain proper function while responding to physiological challenges. Despite previous work investigating morphological and synaptic effects of brain-derived neurotrophic factor
Externí odkaz:
https://doaj.org/article/e1e5c43717a04baca95775a9fd22f1ed
Autor:
Anne P. Ehlers, Alex K. Hallway, Sean M. O'Neill, Brian T. Fry, Ryan A. Howard, Jenny M. Shao, Michael J. Englesbe, Justin B Dimick, Dana A Telem, Grace J Kim
Publikováno v:
Surgery in Practice and Science, Vol 16, Iss , Pp 100235- (2024)
Introduction: Repair of midsize (4–6 cm) ventral hernias is challenging given lack of guidelines. Within this context, we sought to characterize surgical approach among patients undergoing repair of midsize ventral hernias within the only populatio
Externí odkaz:
https://doaj.org/article/f9015fe7a834448bbbb490088e666e79
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 103186- (2024)
Externí odkaz:
https://doaj.org/article/da4353df099f49f9ae1e9d914c993f45
Autor:
Laura-Oana Albulescu, Adam Westhorpe, Rachel H. Clare, Christopher M. Woodley, Nivya James, Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Snakebite envenoming is a neglected tropical disease that causes as many as 1.8 million envenomings and 140,000 deaths annually. To address treatment limitations that exist with current antivenoms, the search for small molecule drug-based inhibitors
Externí odkaz:
https://doaj.org/article/e44e33036d7043608452939fe49851f5
Autor:
Rachel H. Clare, Charlotte A. Dawson, Adam Westhorpe, Laura-Oana Albulescu, Christopher M. Woodley, Nada Mosallam, Daniel J. W. Chong, Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Snakebite envenoming results in ∼100,000 deaths per year, with close to four times as many victims left with life-long sequelae. Current antivenom therapies have several limitations including high cost, variable cross-snake species efficacy and a r
Externí odkaz:
https://doaj.org/article/c67978e66f4041d2bd395e92866c736a
Publikováno v:
BJGP Open, Vol 7, Iss 4 (2023)
Background: The incidence of early-onset colorectal cancer (EOCRC) in adults aged
Externí odkaz:
https://doaj.org/article/38b22c036c1440f782b32e2084e42ff1