Zobrazeno 1 - 10
of 40
pro vyhledávání: '"P M, Kozhin"'
Autor:
Daniil D. Romashin, Tatiana V. Tolstova, Alexandra M. Varshaver, Peter M. Kozhin, Alexander L. Rusanov, Natalia G. Luzgina
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8627-8641 (2024)
Keratins 6, 16, and 17 occupy unique positions within the keratin family. These proteins are not commonly found in the healthy, intact epidermis, but their expression increases in response to damage, inflammation, and hereditary skin conditions, as w
Externí odkaz:
https://doaj.org/article/4e331875fe6f430f90175321a686c65f
Autor:
P. M. Kozhin, A. S. Sementsov, S. E. Khrapov, M. V. Khrapova, L. P. Romakh, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 42, Iss 6, Pp 35-44 (2022)
Oxidative stress is an important mechanism of myocardial damage during ischemia/reperfusion. To investigate the possibility of restoring the redox balance using “indirect” antioxidant effects, the cardioprotective effect Keap1/Nrf2/ ARE system in
Externí odkaz:
https://doaj.org/article/35454f24c9b044708ecf9413609656c3
Autor:
M. V. Khrapova, S. E. Khrapov, A. V. Chechushkov, P. M. Kozhin, L. P. Romakh, A. E. Serykh, S. V. Kholshin, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 42, Iss 5, Pp 11-18 (2022)
One of the promising areas of modern pharmacology is the development of «indirect antioxidants» capable of activating redox-sensitive signaling systems, primarily the Keap1/Nrf2/ARE system. Among its chemical inductors is the hydrophilic monosubsti
Externí odkaz:
https://doaj.org/article/64f0c7ef199e4899abed2cc09b3ca94e
Autor:
S. E. Khrapov, P. M. Kozhin, M. V. Khrapova, A. E. Serykh, L. P. Romakh, V. S. Pavlov, A. V. Chechushkov, S. V. Kholshin, N. K. Zenkov, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 41, Iss 3, Pp 25-31 (2021)
Under certain conditions, both activators and inhibitors of Nrf2-dependent signaling and autophagy can serve as potential agents for the prevention, treatment, and maintenance therapy of cancer, as well as overcoming chemoresistance. We are developin
Externí odkaz:
https://doaj.org/article/b5fda36ed7084758af04b032e864aa8b
Autor:
Daniil D. Romashin, Alexander L. Rusanov, Peter M. Kozhin, Maxim N. Karagyaur, Olga V. Tikhonova, Victor G. Zgoda, Nataliya G. Luzgina
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108274- (2022)
The HaCaT line of immortalized non-tumor cells is a popular model of keratinocytes used for dermatological studies, in the practice of toxicological tests, and in the study of skin allergic reactions. These cells maintain a stable keratinocyte phenot
Externí odkaz:
https://doaj.org/article/26789a792e9f48ad838a00fbd797de1b
Autor:
E. B. Menshchikova, N. K. Zenkov, P. M. Kozhin, A. V. Chechushkov, V. S. Pavlov, L. P. Romakh, M. V. Khrapova, A. E. Serykh, O. B. Gritsyk, N. V. Kandalintseva
Publikováno v:
Сибирский научный медицинский журнал, Vol 40, Iss 6, Pp 58-69 (2020)
Understanding the role of reactive oxygen and nitrogen species in eustress (redox balance) and distress (oxidative stress) development poses new challenges for biomedical scientists and pharmacologists in the search for compounds that can not only ha
Externí odkaz:
https://doaj.org/article/d474da70577948f88ecfc58d526ab64c
Autor:
P. M. Kozhin, A. V. Chechushkov, N. S. Zaytseva, M. V. Khrapova, L. A. Cherdantseva, E. B. Menshchikova, A. V. Troitsky, V. A. Shkurupy
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 4, Pp 22-29 (2019)
The study analyzes the expression of protein genes involved in intracellular signaling pathways associated with a profibrotic response, activation of epithelial-mesenchymal and endothelial-mesenchymal transitions, in modeling tuberculous granulomatos
Externí odkaz:
https://doaj.org/article/842a758e71d946fd996780b105c1304d
Autor:
N. K. Zenkov, A. V. Chehushkov, P. M. Kozhin, G. G. Martinovich, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Бюллетень сибирской медицины, Vol 18, Iss 2, Pp 195-214 (2019)
Autophagy is the main catabolic process required for the removal of damaged organelles, aggregated proteins and intracellular pathogens from cells. Oxidative stress is accompanied by an increase in autophagy, which has a protective effect by maintain
Externí odkaz:
https://doaj.org/article/3dd073a9e9164a6eaa1e66ede1017681
Autor:
N. K. Zenkov, P. M. Kozhin, A. V. Vcherashnyaya, G. G. Martinovich, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 2, Pp 11-26 (2019)
Endogenous mechanisms of reactive oxygen (ROS) and nitrogen species production and of antioxidant defense systems in tumor cells are analyzed. Increased ROS production is an important regulator of metabolic changes in these cells: enhanced proliferat
Externí odkaz:
https://doaj.org/article/57059c42a168468798b406cd20866ae2
Autor:
P. I. Gaynutdinov, P. M. Kozhin, A. V. Chechushkov, G. G. Martinovich, S. V. Kholshin, N. V. Kandalintseva, N. K. Zenkov, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 38, Iss 1, Pp 22-31 (2019)
The aim of the study was to study investigate the relationship between the antioxidant activity of new synthetic structurally related water-soluble monophenols and their effect on the tumor cell viability in vitro. Material and methods. Five original
Externí odkaz:
https://doaj.org/article/9aee845f3df24acb8dba91409904e7aa