Zobrazeno 1 - 10
of 151
pro vyhledávání: '"P M, Christensen"'
Autor:
Zachary T. Calamari, Andrew Song, Emily Cohen, Muspika Akter, Rishi Das Roy, Outi Hallikas, Mona M. Christensen, Pengyang Li, Pauline Marangoni, Jukka Jernvall, Ophir D. Klein
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Continuously growing teeth are an important innovation in mammalian evolution, yet genetic regulation of continuous growth by stem cells remains incompletely understood. Dental stem cells responsible for tooth crown growth are los
Externí odkaz:
https://doaj.org/article/7016d160d0634ccd86d7e97904abdff2
Autor:
Chirag Krishna, Joshua Chiou, Saori Sakaue, Joyce B. Kang, Stephen M. Christensen, Isac Lee, Melis Atalar Aksit, Hye In Kim, David von Schack, Soumya Raychaudhuri, Daniel Ziemek, Xinli Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Genetic variation in the human leukocyte antigen (HLA) loci is associated with risk of immune-mediated diseases, but the molecular effects of HLA polymorphism are unclear. Here we examined the effects of HLA genetic variation on the expressi
Externí odkaz:
https://doaj.org/article/68deecd756d04f759f1d94d794e8cfa3
Autor:
Priya M Christensen, Jonathan Martin, Aparna Uppuluri, Luke R Joyce, Yahan Wei, Ziqiang Guan, Faruck Morcos, Kelli L Palmer
Publikováno v:
eLife, Vol 13 (2024)
Bacterial membranes are complex and dynamic, arising from an array of evolutionary pressures. One enzyme that alters membrane compositions through covalent lipid modification is MprF. We recently identified that Streptococcus agalactiae MprF synthesi
Externí odkaz:
https://doaj.org/article/8f50c391ff6f4343b6b4ff0708c3f9d3
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 21, Pp n/a-n/a (2024)
Abstract The mesoscale spectrum describes the distribution of kinetic energy in the Earth's atmosphere between length scales of 10 and 400 km. Since the first observations, the origins of this spectrum have been controversial. At synoptic scales, the
Externí odkaz:
https://doaj.org/article/1c1548882ed7475aba959ca22efed5c8
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 20, Pp n/a-n/a (2024)
Abstract Clouds are one of the largest sources of uncertainty in climate predictions. Global km‐scale models need to simulate clouds and precipitation accurately to predict future climates. To isolate issues in their representation of clouds, model
Externí odkaz:
https://doaj.org/article/ec524df7883a473dba56ad32cdddb0f9
Autor:
B. Linder, P. Preusse, Q. Chen, O. M. Christensen, L. Krasauskas, L. Megner, M. Ern, J. Gumbel
Publikováno v:
Atmospheric Measurement Techniques, Vol 17, Pp 3829-3841 (2024)
MATS (Mesospheric Airglow/Aerosol Tomography and Spectroscopy) is a Swedish satellite designed to investigate atmospheric dynamics in the mesosphere and lower thermosphere (MLT). By observing structures in noctilucent clouds over polar regions and ox
Externí odkaz:
https://doaj.org/article/e7561257e1ce44328c3fed9c4909da2a
Autor:
Lara Magni, Haoran Yu, Nynne M. Christensen, Mette H. Poulsen, Alexander Frueh, Ganga Deshar, Astrid Z. Johansen, Julia S. Johansen, Stephan A. Pless, Niklas R. Jørgensen, Ivana Novak
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background The purinergic P2X7 receptor (P2X7R) plays an important role in the crosstalk between pancreatic stellate cells (PSCs) and cancer cells, thus promoting progression of pancreatic ductal adenocarcinoma (PDAC). Single nucleotide poly
Externí odkaz:
https://doaj.org/article/fe7eeb715b5d4909a0fb35c22c90c785
Autor:
Harold Edward Bays, Angela Fitch, Carolynn Francavilla Brown, Courtney Younglove, Sandra M. Christensen, Lydia C. Alexander
Publikováno v:
Obesity Pillars, Vol 11, Iss , Pp 100122- (2024)
Background: In 2023, the Obesity Medicine Association (OMA) published “Compounded peptides: An Obesity Medicine Association Position Statement.” Since this publication, the use of compounded peptides for the treatment of obesity has continued to
Externí odkaz:
https://doaj.org/article/39c3c05b625c4057b7707b6d08a8204c
Autor:
Tatiana Akimova, Liqing Wang, Zhanna Bartosh, Lanette M. Christensen, Evgeniy Eruslanov, Sunil Singhal, Veenu Aishwarya, Wayne W. Hancock
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Our goal is to improve the outcomes of cancer immunotherapy by targeting FOXP3+ T-regulatory (Treg) cells with a next generation of antisense oligonucleotides (ASO), termed FOXP3 AUMsilence ASO. We performed in vitro experiments with human healthy do
Externí odkaz:
https://doaj.org/article/a96f23f9055b414882bcdbc8711caf2b
Autor:
Lanette M. Christensen, Tatiana Akimova, Liqing Wang, Rongxiang Han, Arabinda Samanta, Eros Di Giorgio, Wayne W. Hancock
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Histone deacetylases 1 and 2 play a major role in the transcriptional regulation of T-regulatory (Treg) cells via interactions with a myriad of coregulatory factors. Sin3a has been well established as a Hdac1/2 cofactor, while its role within Tregs h
Externí odkaz:
https://doaj.org/article/ce5b2e2a49e74bcd86d6e921a8749fc3