Zobrazeno 1 - 10
of 417
pro vyhledávání: '"P M, Burrell"'
Autor:
Amy Brodtmann, Alex Billett, Rachael Telfer, Kim Adkins, Laura White, Laura J. E. McCambridge, Louise M. Burrell, Vincent Thijs, Sharon Kramer, Emilio Werden, Barbara R. Cardoso, Matthew Pase, Stanley Hughwa Hung, Leonid Churilov, Julie Bernhardt, Kathryn Hayward, Liam Johnson
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Stroke increases subsequent dementia risk yet there are no specific post-stroke therapies to protect cognition. Cardiorespiratory exercise is recommended for secondary prevention of stroke and may be neuroprotective. The Post Isch
Externí odkaz:
https://doaj.org/article/d27dddd1df8d45d2a6a0da7df21bcee6
Autor:
J. M. McGree, C. Hockham, S. Kotwal, A. Wilcox, A. Bassi, C. Pollock, L. M. Burrell, T. Snelling, V. Jha, M. Jardine, M. Jones, for the CLARITY Trial Steering Committee
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract The CLARITY trial (Controlled evaLuation of Angiotensin Receptor Blockers for COVID-19 respIraTorY disease) is a two-arm, multi-centre, randomised controlled trial being run in India and Australia that investigates the effectiveness of angio
Externí odkaz:
https://doaj.org/article/7e102adbaacd4e008f28627da6017f5f
Autor:
Bruce D. Wines, Liriye Kurtovic, Halina M. Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L. Mordant, Wen Shi Lee, Nicholas A. Gherardin, Sheila K. Patel, Gemma E. Hartley, Phillip Pymm, James P. Cooney, James G. Beeson, Dale I. Godfrey, Louise M. Burrell, Menno C. van Zelm, Adam K. Wheatley, Amy W. Chung, Wai-Hong Tham, Kanta Subbarao, Stephen J. Kent, P. Mark Hogarth
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/140fea88883d408989768880a06ffb83
Autor:
Carinna Hockham, Sradha Kotwal, Arlen Wilcox, Abhinav Bassi, James McGree, Carol Pollock, Louise M. Burrell, Nikita Bathla, Mallikarjuna Kunigari, Vinay Rathore, Michael John, Enmoore Lin, Christine Jenkins, Angus Ritchie, Andrew McLachlan, Thomas Snelling, Mark Jones, Vivekanand Jha, Meg Jardine, on behalf of the CLARITY Investigators
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background SARS-CoV-2 binds to membrane-bound angiotensin-converting enzyme 2 (ACE2) which may result in downregulation of membrane-bound ACE2. ACE2 is a key regulator of the renin-angiotensin system (RAS) and is responsible for degrading an
Externí odkaz:
https://doaj.org/article/895cf329e32e4301a5d54c35a2ed5b69
Autor:
Bruce D. Wines, Liriye Kurtovic, Halina M. Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L. Mordant, Wen Shi Lee, Nicholas A. Gherardin, Sheila K. Patel, Gemma E. Hartley, Phillip Pymm, James P. Cooney, James G. Beeson, Dale I. Godfrey, Louise M. Burrell, Menno C. van Zelm, Adam K. Wheatley, Amy W. Chung, Wai-Hong Tham, Kanta Subbarao, Stephen J. Kent, P. Mark Hogarth
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Joining a function-enhanced Fc-portion of human IgG to the SARS-CoV-2 entry receptor ACE2 produces an antiviral decoy with strain transcending virus neutralizing activity. SARS-CoV-2 neutralization and Fc-effector functions of ACE2-Fc decoy proteins,
Externí odkaz:
https://doaj.org/article/3a2991630f9b42fdb65b29d07a0e335f
Autor:
Trine Moholdt, Clifford Afoakwah, Paul Scuffham, Christine F. McDonald, Louise M. Burrell, Simon Stewart
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Although it is known that winter inclusive of the Christmas holiday period is associated with an increased risk of dying compared to other times of the year, very few studies have specifically examined this phenomenon within a pop
Externí odkaz:
https://doaj.org/article/abc3141a2dbe42a0b4faa7fc34909528
Autor:
Jay Ramchand, Pooja Podugu, Nancy Obuchowski, Serge C. Harb, Michael Chetrit, Alex Milinovich, Brian Griffin, Louise M. Burrell, W. H. Wilson Tang, Deborah H. Kwon, Scott D. Flamm
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 8 (2021)
Background Left ventricular non‐compaction remains a poorly described entity, which has led to challenges of overdiagnosis. We aimed to evaluate if the presence of a thin compacted myocardial layer portends poorer outcomes in individuals meeting ca
Externí odkaz:
https://doaj.org/article/5c4a541cd5014af0b3659848613ba6d0
Autor:
Sheila K. Patel, Elena Velkoska, Daniel Gayed, Jay Ramchand, Jessica Lesmana, Louise M. Burrell
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Left ventricular hypertrophy (LVH) increases the risk of death in chronic kidney disease (CKD). The transcription factor Kruppel-like factor 15 (KLF15) is expressed in the heart and regulates cardiac remodelling through inhibition
Externí odkaz:
https://doaj.org/article/e99a810526444f6bb50a14986d88e4b3
Autor:
Simon Stewart, Trine T Moholdt, Louise M Burrell, Karen Sliwa, Ana O Mocumbi, John JV McMurray, Ashley K Keates, John A Hawley
Publikováno v:
Cardiac Failure Review, Vol 5, Iss 2, Pp 83-85 (2019)
Climate change is a major contributor to annual winter peaks in cardiovascular events across the globe. However, given the paradoxical observation that cardiovascular seasonality is observed in relatively mild as well as cold climates, global warming
Externí odkaz:
https://doaj.org/article/01cb405dfdbf42d9b64d5e704a6aa10a
Autor:
Sheila K. Patel, Carolina Restrepo, Emilio Werden, Leonid Churilov, Elif I. Ekinci, Piyush M. Srivastava, Jay Ramchand, Bryan Wai, Brian Chambers, Christopher J. O’Callaghan, David Darby, Vladimir Hachinski, Toby Cumming, Geoff Donnan, Louise M. Burrell, Amy Brodtmann
Publikováno v:
BMC Endocrine Disorders, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Cognitive impairment is common in type 2 diabetes mellitus, and there is a strong association between type 2 diabetes and Alzheimer’s disease. However, we do not know which type 2 diabetes patients will dement or which biomarker
Externí odkaz:
https://doaj.org/article/a22ed629b73741afa0b1d4cbf53962e2