Zobrazeno 1 - 10
of 172
pro vyhledávání: '"P M, Barnes"'
Autor:
Melissa C. White, Julia E. Canick, Tariq M. Omer, Justin M. Barnes, William T. Reed, Rebecca L. Rohde, Dina K. Abouelella, Eric Adjei Boakye, Katherine Ramos, Russel R. Kahmke, Nosayaba Osazuwa-Peters
Publikováno v:
BJC Reports, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract Background With more than 15,000 annual deaths from head and neck cancer (HNC), an important aspect of end-of-life care for these patients is place of death. Recent evidence suggests an increasing preference for home/hospice at end of life;
Externí odkaz:
https://doaj.org/article/b44c9767532743998629bf1f4bffd393
Autor:
Omar S. Qureshi, Emma J. Sutton, Rosemary F. Bithell, Shauna M. West, Rona M. Cutler, Gillian McCluskey, Graham Craggs, Asher Maroof, Nicholas M. Barnes, David P. Humphreys, Stephen Rapecki, Bryan J. Smith, Anthony Shock
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTRozanolixizumab is a humanized anti-neonatal Fc receptor (FcRn) monoclonal antibody (mAb) of the immunoglobulin G4 (IgG4) sub-class, currently in clinical development for the treatment of IgG autoantibody-driven diseases. This format is frequ
Externí odkaz:
https://doaj.org/article/f74b0a47f067425f9e3ed7abc893041a
Autor:
Aidan Anderson, Nada Alfahad, Dulani Wimalachandra, Kaouthar Bouzinab, Paula Rudzinska, Heather Wood, Isabel Fazey, Heping Xu, Timothy J. Lyons, Nicholas M. Barnes, Parth Narendran, Janet M. Lord, Saaeha Rauz, Ian G. Ganley, Tim M. Curtis, Graham R. Wallace, Jose R. Hombrebueno
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The recovery of mitochondrial quality control (MQC) may bring innovative solutions for neuroprotection, while imposing a significant challenge given the need of holistic approaches to restore mitochondrial dynamics (fusion/fission) and turno
Externí odkaz:
https://doaj.org/article/49bb462680fd472a9c0826d8dc86da53
Autor:
Stella Cochrane, Ramya Rajagopal, David Sheffield, Fay Stewart, Lindsay Hathaway, Nicholas M. Barnes, Omar Qureshi, John Gordon
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Introduction: In toxicology, steps are being taken towards more mechanism-focused and human relevant approaches to risk assessment, requiring new approaches and methods. Additionally, there is increasing emphasis by regulators on risk assessment of i
Externí odkaz:
https://doaj.org/article/f4cb27fd0f7340f38632140be550ef16
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Large-scale quantum computers have the potential to hold computational capabilities beyond conventional computers. However, the physical qubits are prone to noise which must be corrected in order to perform fault-tolerant quantum computation
Externí odkaz:
https://doaj.org/article/fe534eed8b51446f8cf3c1746975769f
Autor:
Edward R. Palmer, Siân Lowri Griffiths, Ben Watkins, Tyler Weetman, Ryan Ottridge, Smitaa Patel, Rebecca Woolley, Sarah Tearne, Pui Au, Eleanor Taylor, Zara Sadiq, Hareth Al-Janabi, Barnaby Major, Charlotte Marriott, Nusrat Husain, Mohammad Zia Ul Haq Katshu, Domenico Giacco, Nicholas M. Barnes, James T. R. Walters, Thomas R. E. Barnes, Max Birchwood, Richard Drake, Rachel Upthegrove
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Depressive episodes are common after first-episode psychosis (FEP), affecting more than 40% of people, adding to individual burden, poor outcomes, and healthcare costs. If the risks of developing depression were lower, this could
Externí odkaz:
https://doaj.org/article/44f228a1a8da45fc9e082bf89cc9d09d
Autor:
Sarah E. Herniman, Stephen J. Wood, Golam Khandaker, Paola Dazzan, Carmine M. Pariante, Nicholas M. Barnes, Carl R. Krynicki, Naghmeh Nikkheslat, Rachel C. Vincent, Alex Roberts, Annalisa Giordano, Andrew Watson, John Suckling, Thomas R. E. Barnes, Nusrat Husain, Peter B. Jones, Eileen Joyce, Stephen M. Lawrie, Shôn Lewis, Bill Deakin, Rachel Upthegrove, the BeneMin Study Team
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Attempts to delineate an immune subtype of schizophrenia have not yet led to the clear identification of potential treatment targets. An unbiased informatic approach at the level of individual immune cytokines and symptoms may reveal organis
Externí odkaz:
https://doaj.org/article/77b87667f96046caa3e615dd5523de90
Autor:
Michael Owen-Bellini, James Y. Hartley, Anubhav Jain, Dirk C. Jordan, Laura T. Schelhas, Teresa M. Barnes
Publikováno v:
PRX Energy, Vol 3, Iss 2, p 021001 (2024)
Durable and reliable photovoltaic (PV) modules are critical to enabling an efficient transition to sustainable energy generation. The rate at which new module designs and materials are developed and deployed currently outpaces the rate at which we ca
Externí odkaz:
https://doaj.org/article/6f3d363f835640d18f9801540461ca4a
Autor:
Larance Ronsard, Ashraf S. Yousif, Faez Amokrane Nait Mohamed, Jared Feldman, Vintus Okonkwo, Caitlin McCarthy, Julia Schnabel, Timothy Caradonna, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, Aaron Schmidt, Daniel Lingwood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Low affinity is common for germline B cell receptors (BCR) seeding development of broadly neutralizing antibodies (bnAbs) that engage hypervariable viruses, including HIV. Antibody affinity selection is also non-homogenizing, insuring the su
Externí odkaz:
https://doaj.org/article/a0cd14beccbe4760b5405b63d07f7e21
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303280 (2024)
BackgroundAccess to breast screening mammogram services decreased during the COVID-19 pandemic. Our objectives were to estimate: 1) the COVID-19 affected period, 2) the proportion of pandemic-associated missed or delayed screening encounters, and 3)
Externí odkaz:
https://doaj.org/article/de16793cfcc24577981d92d8fd708e08