Dysregulated Inflammatory Cytokine Levels May Be Useful Markers in a Better Up-Dated Management of COVID-19

Autor: Marco Iuliano, Roberta Maria Mongiovì, Alberico Parente, Blerta Kertusha, Anna Carraro, Raffaella Marocco, Giulia Mancarella, Cosmo Del Borgo, Laura Fondaco, Lorenzo Grimaldi, Maria Dorrucci, Miriam Lichtner, Giorgio Mangino, Giovanna Romeo

Publikováno v: Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8890-8902 (2024)

Coronavirus disease 2019 (COVID-19) is an infection characterized by the dysregulation of systemic cytokine levels. The measurement of serum levels of inflammatory cyto-/chemokines has been suggested as a tool in the management of COVID-19. The aim o

Externí odkaz: https://doaj.org/article/1008d1eee38c4a2dacdb0f14f70f8d42

Clinical and laboratory predictors of mpox severity and duration: an Italian multicentre cohort study (mpox-Icona)Research in context

Autor: Valentina Mazzotta, Silvia Nozza, Simone Lanini, Davide Moschese, Alessandro Tavelli, Roberto Rossotti, Francesco Maria Fusco, Lorenzo Biasioli, Giulia Matusali, Angelo Roberto Raccagni, Davide Mileto, Chiara Maci, Giuseppe Lapadula, Antonio Di Biagio, Luca Pipitò, Enrica Tamburrini, Antonella d’Arminio Monforte, Antonella Castagna, Andrea Antinori, Spinello Antinori, Chiara Baiguera, Gianmaria Baldin, Matteo Bassetti, Paolo Bonfanti, Giorgia Brucci, Elena Bruzzesi, Caterina Candela, Antonio Cascio, Antonella d'Arminio Monforte, Andrea Delama, Gabriella D'Ettorre, Damiano Farinacci, Maria Rita Gismondo, Andrea Gori, Massimiliano Lanzafame, Miriam Lichtner, Giulia Mancarella, Alessandro Mancon, Giulia Marchetti, Emanuele Nicastri, Alessandro Pandolfo, Francesca Panzo, Stefania Piconi, Carmela Pinnetti, Alessandro Raimondi, Marco Ridolfi, Giuliano Rizzardini, Alessandra Rodanò, Margherita Sambo, Vincenzo Sangiovanni, Nadia Sangiovanni, Daniele Tesoro, Serena Vita

Publikováno v: EBioMedicine, Vol 107, Iss , Pp 105289- (2024)

Summary: Background: Severe and prolonged mpox courses have been described during the 2022–2023 outbreak. Identifying predictors of severe evolution is crucial for improving management and therapeutic strategies. We explored the predictors of mpox

Externí odkaz: https://doaj.org/article/ee0528c861034ad8aa54758b34334546

Association Between NOX2-Mediated Oxidative Stress, Low-Grade Endotoxemia, Hypoalbuminemia, and Clotting Activation in COVID-19

Autor: Roberto Carnevale, Cristina Nocella, Raffaella Marocco, Paola Zuccalà, Anna Carraro, Vittorio Picchio, Alessandra Oliva, Roberto Cangemi, Maria Claudia Miele, Massimiliano De Angelis, Francesca Cancelli, Giovanni Enrico Casciaro, Luca Cristiano, Pasquale Pignatelli, Giacomo Frati, Mario Venditti, Francesco Pugliese, Claudio Maria Mastroianni, Francesco Violi, Lorenzo Ridola, Cosmo Del Borgo, Silvia Palmerio, Emiliano Valenzi, Rita Carnevale, Domenico Alvaro, Miriam Lichtner, Vincenzo Cardinale

Publikováno v: Antioxidants, Vol 13, Iss 10, p 1260 (2024)

Low-grade endotoxemia by lipopolysaccharide (LPS) has been detected in COVID-19 and could favor thrombosis via eliciting a pro-inflammatory and pro-coagulant state. The aim of this study was to analyze the mechanism accounting for low-grade endotoxem

Externí odkaz: https://doaj.org/article/6a20017cb7fa447a902f0e4847c8a1db

Immunogenicity and reactogenicity of modified vaccinia Ankara pre-exposure vaccination against mpox according to previous smallpox vaccine exposure and HIV infection: prospective cohort studyResearch in context

Autor: Valentina Mazzotta, Alessandro Cozzi Lepri, Giulia Matusali, Eleonora Cimini, Pierluca Piselli, Camilla Aguglia, Simone Lanini, Francesca Colavita, Stefania Notari, Alessandra Oliva, Silvia Meschi, Rita Casetti, Vanessa Mondillo, Alessandra Vergori, Aurora Bettini, Germana Grassi, Carmela Pinnetti, Daniele Lapa, Eleonora Tartaglia, Paola Gallì, Annalisa Mondi, Giulia Montagnari, Roberta Gagliardini, Emanuele Nicastri, Miriam Lichtner, Loredana Sarmati, Enrica Tamburrini, Claudio Mastroianni, Christof Stingone, Andrea Siddu, Alessandra Barca, Carla Fontana, Chiara Agrati, Enrico Girardi, Francesco Vaia, Fabrizio Maggi, Andrea Antinori, Enza Anzalone, Marta Camici, Fabio Cannone, Priscilla Caputi, Claudia Cimaglia, Rita Corso, Flavia Cristofanelli, Stefania Cruciani, Nicola De Marco, Chiara De Ponte, Giulia Del Duca, Paolo Faccendini, Francesca Faraglia, Augusto Faticoni, Marisa Fusto, Saba Gebremeskel, Maria Letizia Giancola, Giuseppina Giannico, Simona Gili, Maria Rosaria Iannella, Angela Junea, Alessandra Lamonaca, Alessandra Marani, Erminia Masone, Ilaria Mastrorosa, Stefania Mazzotta, Alessandra Nappo, Giorgia Natalini, Alfredo Parisi, Sara Passacantilli, Jessica Paulicelli, Maria Maddalena Plazzi, Adriano Possi, Gianni Preziosi, Silvia Rosati, Marika Rubino, Pietro Scanzano, Laura Scorzolini, Virginia Tomassi, Maurizio Vescovo, Serena Vita, Luciano Caterini, Luigi Coppola, Dimitra Kontogiannis, Gabriella D'Ettorre, Marco Ridolfi, Simona Di Giambenedetto, Damiano Farinacci, Alessandra Latini, Mauro Marchili, Raffaella Marocco

Publikováno v: EClinicalMedicine, Vol 68, Iss , Pp 102420- (2024)

Summary: Background: Pre-exposure vaccination with MVA-BN has been widely used against mpox to contain the 2022 outbreak. Many countries have defined prioritized strategies, administering a single dose to those historically vaccinated for smallpox, t

Externí odkaz: https://doaj.org/article/ca4f7789ccd24dc59dd11b518dd6da6b

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