Zobrazeno 1 - 10
of 278
pro vyhledávání: '"P Leslie, Dutton"'
Autor:
Nathan M. Ennist, Zhenyu Zhao, Steven E. Stayrook, Bohdana M. Discher, P. Leslie Dutton, Christopher C. Moser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
De novo development of a simplified photosynthetic reaction center protein can clarify practical engineering principles needed to build enzymes for efficient energy conversion. Here, the authors develop an artificial photosynthetic reaction center th
Externí odkaz:
https://doaj.org/article/ecdd0ca5f37f4717bc903f4f1fb1bb45
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
New technologies for efficient solar-to-fuel energy conversion will help facilitate a global shift from dependence on fossil fuels to renewable energy. Nature uses photosynthetic reaction centers to convert photon energy into a cascade of electron-tr
Externí odkaz:
https://doaj.org/article/5d9ffd0e31194d27942cee1805e0842b
Publikováno v:
The Journal of Physical Chemistry B. 126:8177-8187
Oxidoreductases have evolved over millions of years to perform a variety of metabolic tasks crucial for life. Understanding how these tasks are engineered relies on delivering external electron donors or acceptors to initiate electron transfer reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9646e6ce0e45c2f47e387f5217883d4
https://doi.org/10.1021/acs.jpcb.2c05119
https://doi.org/10.1021/acs.jpcb.2c05119
Autor:
P. Leslie Dutton, Christopher C. Moser, Bohdana M. Discher, Zhenyu Zhao, Nathan M. Ennist, Steven Stayrook
Publikováno v:
Nature communications. 13(1)
Natural photosynthetic protein complexes capture sunlight to power the energetic catalysis that supports life on Earth. Yet these natural protein structures carry an evolutionary legacy of complexity and fragility that encumbers protein reengineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5418ac454cf9e5dccd4939252a917df6
https://pubmed.ncbi.nlm.nih.gov/35999239
https://pubmed.ncbi.nlm.nih.gov/35999239
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148558
Quinones play important roles in biological electron transfer reactions in almost all organisms, with specific roles in many physiological processes and chemotherapy. Quinones participate in two-electron, two-proton reactions in aqueous solution at e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6bf1b4dbfc1ca19df3f06fcd39ece7
https://doi.org/10.1016/j.bbabio.2022.148558
https://doi.org/10.1016/j.bbabio.2022.148558
Autor:
Christopher C. Moser, P. Leslie Dutton
Publikováno v:
Protein Electron Transfer ISBN: 9781003076803
The chemiosmotic hypothesis describes the central feature of biological energy transduction as the creation of a transmembrane proton gradient from redox potential energy of photosynthesis and respiration. The gradient is built up by a series of guid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::325dee452e9d08219f74e792ff6e629a
https://doi.org/10.1201/9781003076803-1
https://doi.org/10.1201/9781003076803-1
Autor:
Shuangqing Wang, David G. Bossanyi, James P. Pidgeon, John E. Anthony, Daniel Polak, David J. K. Swainsbury, George A. Sutherland, Andrew Hitchcock, Frank C. Spano, Andrew J. Musser, Dirk B. Auman, C. Neil Hunter, P. Leslie Dutton, Jenny Clark
Publikováno v:
Journal of the American Chemical Society. 142(32)
Advances in protein design and engineering have yielded peptide assemblies with enhanced and non-native functionalities. Here, various molecular organic semiconductors (OSCs), with known excitonic up- and down-conversion properties, are attached to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1627ed022e1574c5ca879d455eb245de
https://pubmed.ncbi.nlm.nih.gov/32672948
https://pubmed.ncbi.nlm.nih.gov/32672948
Autor:
Michael S. Magaraci, Christopher C. Moser, Ivan A. Kuznetsov, P. Leslie Dutton, Joshua A. Mancini, Molly M. Sheehan, Goutham Kodali, Brian Y. Chow
Publikováno v:
Biochemistry
We report the rational construction of a de novo-designed biliverdin-binding protein by first principles of protein design, informed by energy minimization modeling in Rosetta. The self-assembling tetrahelical bundles bind biliverdin IXa (BV) cofacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43aef3543e2a3e1157369bd2d655150
http://europepmc.org/articles/PMC6293442
http://europepmc.org/articles/PMC6293442
Autor:
Goutham Kodali, Joshua A. Mancini, Pawel Wagner, David L. Officer, Christopher J. Hobbs, Christopher C. Moser, Lee A. Solomon, Jonathan E. Barnsley, Kunche Aravindu, Nicholas Roach, Tatiana V. Episova, P. Leslie Dutton, Olga Mass, Keith C. Gordon
Publikováno v:
Chemical Science
Design of nanometer scale artificial light harvesting and charge separating proteins enables reengineering to overcome the limitations of natural selection for efficient systems that better meet human energetic needs.
Natural selection in photos
Natural selection in photos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3814d2461b81c53883c3a6f659dff0
https://doi.org/10.1039/c6sc02417c
https://doi.org/10.1039/c6sc02417c
Autor:
Rylee A. McBride, Chris Bialas, Dirk B. Auman, P. Leslie Dutton, Robert J. Stanley, David T. Barnard, P. J. Hore, Lauren E. Jarocha, Christopher C. Moser
Publikováno v:
Phys Chem Chem Phys
Radical pair formation and decay are implicated in a wide range of biological processes including avian magnetoreception. However, studying such biological radical pairs is complicated by both the complexity and relative fragility of natural systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ac888abcc3d06e16df18eead2a7bfd
https://pubmed.ncbi.nlm.nih.gov/31187821
https://pubmed.ncbi.nlm.nih.gov/31187821