Zobrazeno 1 - 10
of 26
pro vyhledávání: '"P L van Lent"'
CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis
Autor:
Wessel F. Theeuwes, Irene Di Ceglie, Daphne N. Dorst, Arjen B. Blom, Desiree L. Bos, Thomas Vogl, Sander W. Tas, Pilar Jimenez-Royo, Mats Bergstrom, Matthew Cleveland, Peter M. van der Kraan, Peter Laverman, Marije I. Koenders, Peter L. van Lent, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Rheumatoid arthritis (RA) is one of the most prevalent and debilitating joint diseases worldwide. RA is characterized by synovial inflammation (synovitis), which is linked to the development of joint destruction. Magnetic resonanc
Externí odkaz:
https://doaj.org/article/2aad6123f8ac4ee5adcf05a7f4fb72f2
Autor:
Joyce Aarts, Arjan van Caam, Xinlai Chen, Renoud J. Marijnissen, Monique M. Helsen, Birgitte Walgreen, Elly L. Vitters, Fons A. van de Loo, Peter L. van Lent, Peter M. van der Kraan, Marije I. Koenders
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract TGF-β1 is an important growth factor to promote the differentiation of T helper 17 (Th17) and regulatory T cells (Treg). The potential of TGF-β1 as therapeutic target in T cell-mediated diseases like rheumatoid arthritis (RA) is unclear. W
Externí odkaz:
https://doaj.org/article/e56341f6fbb745499f284ebee7d9f397
Autor:
Arjen B. Blom, Martijn H. van den Bosch, Esmeralda N. Blaney Davidson, Johannes Roth, Thomas Vogl, Fons A. van de Loo, Marije Koenders, Peter M. van der Kraan, Edwin J. Geven, Peter L. van Lent
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-15 (2020)
Abstract Background Synovitis-associated pain is mediated by inflammatory factors that may include S100A8/9, which is able to stimulate nociceptive neurons via Toll-like receptor 4. In this study, we investigated the role of S100A9 in pain response d
Externí odkaz:
https://doaj.org/article/0d3325c14e2f4f258d2c206fd533edb7
Autor:
Debbie M Roeleveld, Renoud J Marijnissen, Birgitte Walgreen, Monique M Helsen, Liduine van den Bersselaar, Fons A van de Loo, Peter L van Lent, Peter M van der Kraan, Wim B van den Berg, Marije I Koenders
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development is initiated by combined signaling of TGF-β and IL-6 or IL-21, and can be reduc
Externí odkaz:
https://doaj.org/article/78384ac380dc442c8a8468639da74800
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54016 (2013)
BACKGROUND: To determine the effects of liposomal targeting of prednisolone phosphate (Lip-PLP) to synovial lining macrophages on M1 and M2 polarization in vitro and during experimental arthritis. MATERIAL AND METHODS: Experimental arthritis (antigen
Externí odkaz:
https://doaj.org/article/4ac0fe0b07424525b2a61d62bc5dafcc
Autor:
M H van den Bosch, A B Blom, S W F Suen, A E van Erp, F A van de Loo, E N Blaney Davidson, P M van der Kraan, P L van Lent, W B van den Berg
Publikováno v:
Annals of the Rheumatic Diseases. 73:A66.1-A66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::444dfc68a56204136ff12917e9568c8c
https://doi.org/10.1136/annrheumdis-2013-205124.150
https://doi.org/10.1136/annrheumdis-2013-205124.150
Publikováno v:
Journal of leukocyte biology. 70(5)
Previously we have shown that synovial lining macrophages (SLMs) determine the onset of experimental immune complex-mediated arthritis (ICA). During joint inflammation, many leukocytes undergo apoptosis, and removal of leukocytes by SLMs may regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::796056a815f6607ba8f2df4e62a8a163
https://pubmed.ncbi.nlm.nih.gov/11698489
https://pubmed.ncbi.nlm.nih.gov/11698489
Autor:
P, Barrera, A, Blom, P L, van Lent, L, van Bloois, J H, Beijnen, N, van Rooijen, M C, de Waal Malefijt, L B, van de Putte, G, Storm, W B, van den Berg
Publikováno v:
Arthritis and rheumatism. 43(9)
To assess whether intraarticular (IA) administration of clodronate liposomes results in local macrophage depletion in patients with rheumatoid arthritis (RA). Primary goals were to address both the immunohistologic and potential toxic effects of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e46f030d7b970d5b3f65729f47df5104
https://pubmed.ncbi.nlm.nih.gov/11014344
https://pubmed.ncbi.nlm.nih.gov/11014344
Publikováno v:
Arthritis and rheumatism. 43(9)
Sulfasalazine (SSZ) is a commonly used drug in the treatment of inflammatory diseases such as rheumatoid arthritis and Crohn's disease. In both diseases, the proinflammatory cytokine tumor necrosis factor alpha (TNFalpha) plays a prominent role. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3b3c08af962e2f359d237b9a64e2206
https://pubmed.ncbi.nlm.nih.gov/11014343
https://pubmed.ncbi.nlm.nih.gov/11014343
Autor:
P L, van Lent, A J, van Vuuren, A B, Blom, A E, Holthuysen, L B, van de Putte, J G, van de Winkel, W B, van den Berg
Publikováno v:
Arthritis and rheumatism. 43(4)
To study the role of Fc receptor (FcR) gamma chain in inflammation and cartilage destruction during antigen-induced arthritis (AIA).FcR gamma-/- mice and controls were immunized with methylated bovine serum albumin (mBSA) in Freund's complete adjuvan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd2d5115279faeabef1296dbbb8b34f6
https://pubmed.ncbi.nlm.nih.gov/10765918
https://pubmed.ncbi.nlm.nih.gov/10765918