Zobrazeno 1 - 10 of 34 pro vyhledávání: '"P L Mottram"'
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Akademický článek
Quantifying the δ15N trophic offset in a cold-water scleractinian coral (CWC): implications for the CWC diet and coral δ15N as a marine N cycle proxy
Autor: J. L. Mottram, A. M. Gothmann, M. G. Prokopenko, A. Cordova, V. Rollinson, K. Dobkowski, J. Granger
Publikováno v: Biogeosciences, Vol 21, Pp 1071-1091 (2024)
The nitrogen (N) isotope composition (δ15N) of cold-water corals is a promising proxy for reconstructing past ocean N cycling, as a strong correlation was found between the δ15N of the organic nitrogen preserved in coral skeletons and the δ15N of
Externí odkaz: https://doaj.org/article/d32e79ce632045489c1d574a87b125c8
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2
Modified technique for kidney transplantation in mice
Autor: W R, Han, L J, Murray-Segal, P L, Mottram
Publikováno v: Microsurgery. 19(6)
This study describes a new method for joining the donor ureter to the recipient bladder during mouse kidney transplantation. The donor left kidney was harvested using methods previously published, except that bladder tissue was not harvested with the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ccf1bbfa6e99148e5175eb8552a18790
https://pubmed.ncbi.nlm.nih.gov/10469441
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3
Redefining peripheral tolerance in the BALB/c to CBA mouse cardiac allograft model: vascular and cytokine analysis after transient CD4 T cell depletion
Autor: P L, Mottram, A, Raisanen-Sokolowski, T, Glysing-Jensen, A N, Stein-Oakley, M E, Russell
Publikováno v: Transplantation. 66(11)
To evaluate cardiac allografts from recipients that had achieved peripheral tolerance after transient CD4+ T cell depletion, we analyzed cellular infiltrate, cytokine expression, and vascular thickening. Long-surviving cardiac allografts from toleran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bdf493179ff0350016072fb5c247ad5e
https://pubmed.ncbi.nlm.nih.gov/9869093
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4
Cardiac allografts from IL-4 knockout recipients: assessment of transplant arteriosclerosis and peripheral tolerance
Autor: P L, Mottram, A, Räisänen-Sokolowski, T, Glysing-Jensen, A N, Stein-Oakley, M E, Russell
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(2)
To study the role of IL-4 in tolerance induction and transplant arteriosclerosis, BALB/c hearts were transplanted into C57BL/6J wild-type or IL-4 knockout (IL-4(-/-)) recipients. A 30-day course of anti-CD4/8 mAb was used to induce long term graft su
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d347f3e4338c5b91ab6365880b70be6e
https://pubmed.ncbi.nlm.nih.gov/9670933
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5
Interleukin (IL) 4, the cytokine that isn't there: reactivity of IL-4 antibodies with cells in IL-4 -/- mice
Autor: P L, Mottram, L J, Purcell, W R, Han, J, Maguire, A N, Stein-Oakley
Publikováno v: Transplantation. 63(6)
We analyzed cytokine expression in recipient spleens and cardiac allografts placed in mice that were unable to synthesize interleukin (IL)-4 due to disruption of the IL-4 gene (IL-4 -/-) and in wild-type (IL-4 +/+) mice. Polyclonal BL-4P and monoclon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be49805d4de03d22b9e16d1eeffdb2fd
https://pubmed.ncbi.nlm.nih.gov/9089237
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8
Prevention of both rejection and recurrence of autoimmune disease in the NOD/Lt mouse following segmental pancreas transplantation
Autor: L J, Purcell, P L, Mottram
Publikováno v: Transplantation proceedings. 27(3)
In the NOD/Lt recipient mice, disease recurrence in untreated isografts was extremely rapid (median less than 10 days) compared to the rejection of an untreated BALB/c pancreas graft in a CBA mouse (median 26 days). This would be expected since disea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfa73a6c296ab00ff194b419610a4983
https://pubmed.ncbi.nlm.nih.gov/7792922
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9
Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-gamma in long-surviving mouse heart allografts after brief CD4-monoclonal antibody therapy
Autor: P L, Mottram, W R, Han, L J, Purcell, I F, McKenzie, W W, Hancock
Publikováno v: Transplantation. 59(4)
In a mouse model for vascularized heart transplantation, CBA recipients of BALB/c hearts were treated with 0.25 mg of anti-CD4 (GK1.5) given intraperitoneally on the day of grafting and on days 1, 2, and 3 thereafter. This reduced splenic CD4+ cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd82d3719b29f55d570854daaf3ad598
https://pubmed.ncbi.nlm.nih.gov/7878761
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