Zobrazeno 1 - 8
of 8
pro vyhledávání: '"P L Dabkowski"'
Publikováno v:
Xenotransplantation. 1:81-88
Galoα(l,3)Gal is a terminal carbohydrate found on many glycosylated cell surface molecules of species other than humans and Old World monkeys, and is produced by the α(l,3)galactosyl transferase enzyme's adding galactose to a substrate. We have pre
Publikováno v:
Transplantation proceedings. 26(3)
Publikováno v:
Transplantation proceedings. 26(3)
Autor:
Pei Xiang Xing, Hilary A. Vaughan, Julie Prenzoska, Mauro S. Sandrin, P. L. Dabkowski, Ian F. C. McKenzie
Publikováno v:
Transplant immunology. 2(2)
We have previously demonstrated that the major epitope in pig tissues detected by naturally occurring human IgM antibodies is galactose(α1–3)galactose. Subsequent biochemical studies demonstrated this epitope to be present on molecules ( M r 40–
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 90(23)
A major problem with pig-to-human-tissue xenograft studies is that humans have natural antibodies to pig cells; these antibodies would cause hyperacute rejection if pig tissues were xenografted to humans. Here we show that most of human IgM antibodie
Publikováno v:
Transplantation proceedings. 25(5)
Publikováno v:
Transplantation proceedings. 25(5)
Publikováno v:
BMJ. 306:1726-1726
Idiopathic haemochromatosis is an inherited defect of iron metabolism characterised by excessive iron absorption and deposition in the tissues leading to damage in the liver and other organs.' The nature of the fundamental metabolic abnormality remai