Zobrazeno 1 - 10
of 68
pro vyhledávání: '"P L A van Daele"'
Autor:
Alberto Iannuzzo, Selket Delafontaine, Rana El Masri, Rachida Tacine, Giusi Prencipe, Masahiko Nishitani-Isa, Rogier T. A. van Wijck, Farzana Bhuyan, Adriana A. de Jesus Rasheed, Simona Coppola, Paul L. A. van Daele, Antonella Insalaco, Raphaela Goldbach-Mansky, Takahiro Yasumi, Marco Tartaglia, Isabelle Meyts, Jérôme Delon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Most autoinflammatory diseases are caused by mutations in innate immunity genes. Previously, four variants in the RHO GTPase CDC42 were discovered in patients affected by syndromes generally characterized by neonatal-onset of cytopenia and a
Externí odkaz:
https://doaj.org/article/17cad2248ee74a9f993423959575bbb9
Bioinformatic meta-analysis reveals novel differentially expressed genes and pathways in sarcoidosis
Autor:
Rogier T. A. van Wijck, Hari S. Sharma, Sigrid M. A. Swagemakers, Willem A. Dik, Hanna IJspeert, Virgil A. S. H. Dalm, Paul L. A. van Daele, P. Martin van Hagen, Peter J. van der Spek
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionSarcoidosis is a multi-system inflammatory disease of unknown origin with heterogeneous clinical manifestations varying from a single organ non-caseating granuloma site to chronic systemic inflammation and fibrosis. Gene expression studie
Externí odkaz:
https://doaj.org/article/f8a6d8e6b3d74c478ef8b365b23c0637
Autor:
Ikhwanuliman Putera, Paul L. A. van Daele, Josianne C. E. M. ten Berge, Willem A. Dik, Rina La Distia Nora, P. Martin van Hagen, Saskia M. Rombach
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
IntroductionThere is a scarcity of long-term follow-up data and management strategies for recurrent uveitis in tubercular uveitis (TBU), especially in cases extending beyond 10 years after the completion of initial antitubercular treatment (ATT).Meth
Externí odkaz:
https://doaj.org/article/477dc772d04545c5b7f6042f2add5557
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Autoinflammatory diseases are rare disorders of the innate immune system characterized by fever and other signs of inflammation. A feared complication of autoinflammatory diseases is the development of AA amyloidosis. AA amyloidos
Externí odkaz:
https://doaj.org/article/580038b4b5fb46d6841240b46319a593
Autor:
P. Martijn Kolijn, Erika Huijser, M. Javad Wahadat, Cornelia G. van Helden-Meeuwsen, Paul L. A. van Daele, Zana Brkic, Jos Rijntjes, Konnie M. Hebeda, Patricia J. T. A. Groenen, Marjan A. Versnel, Rogier M. Thurlings, Anton W. Langerak
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionActivated B cells play a key role in the pathogenesis of primary Sjögren’s syndrome (pSS) through the production of autoantibodies and the development of ectopic germinal centers in the salivary glands and other affected sites. Around
Externí odkaz:
https://doaj.org/article/f8ad4e01c67f479783c7d60574855f40
Autor:
Erika Huijser, Cornelia G. van Helden-Meeuwsen, Dwin G. B. Grashof, Jessica R. Tarn, Zana Brkic, Josje M. A. Huisman, M. Javad Wahadat, Harmen J. G. van de Werken, Ana P. Lopes, Joel A. G. van Roon, Paul L. A. van Daele, Sylvia Kamphuis, Wan-Fai Ng, Siroon Bekkering, Leo A. B. Joosten, Willem A. Dik, Marjan A. Versnel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundTrained immunity – or innate immune memory – can be described as the long-term reprogramming of innate immune cells towards a hyperresponsive state which involves intracellular metabolic changes. Trained immunity has been linked to athe
Externí odkaz:
https://doaj.org/article/72f7b5e73ccf4457a9a39a2512306f2e
Autor:
Maud A. W. Hermans, Astrid C. van Stigt, Sanne van de Meerendonk, Benjamin Schrijver, Paul L. A. van Daele, Petrus M. van Hagen, Marloes van Splunter, Willem A. Dik
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The Mas-related G-protein-coupled receptor X2 (MRGPRX2) is prominently expressed by mast cells and induces degranulation upon binding by different ligands. Its activation has been linked to various mast cell-related diseases, such as chronic spontane
Externí odkaz:
https://doaj.org/article/cb6080b5e5f1497dab73576c78c44bba
Autor:
Laixi Xue, K. van Bilsen, M. W. J. Schreurs, M. E. J. van Velthoven, T. O. Missotten, A. A. H. J. Thiadens, R. W. A. M. Kuijpers, P. van Biezen, V. A. S. H. Dalm, J. A. M. van Laar, M. A. W. Hermans, W. A. Dik, P. L. A. van Daele, P. M. van Hagen
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: Since the late ‘90s, infliximab (Remicade®) is being used successfully to treat patients with several non-infectious immune mediated inflammatory diseases (IMIDs). In recent years, infliximab biosimilars, including Remsima® were intro
Externí odkaz:
https://doaj.org/article/e152d3e8b46f4c7a951758b552d87606
Autor:
Catharina M. Mulders-Manders, Tim A. Kanters, Paul L. A. van Daele, Esther Hoppenreijs, G. Elizabeth Legger, Jan A. M. van Laar, Anna Simon, Leona Hakkaart-van Roijen
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-8 (2018)
Abstract Background Cryopyrin-associated periodic syndrome (CAPS) is a rare disease. Knowledge on the quality of life (QoL) and the disease’s societal impact is limited. Canakinumab is used in increasing frequency for the treatment of CAPS. Methods
Externí odkaz:
https://doaj.org/article/06ed263f127049a18feb160b88292e63
Autor:
Iris L. A. Bodewes, Peter J. van der Spek, Leticia G. Leon, Annemarie J. M. Wijkhuijs, Cornelia G. van Helden-Meeuwsen, Liselotte Tas, Marco W. J. Schreurs, Paul L. A. van Daele, Peter D. Katsikis, Marjan A. Versnel
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease, where patients often suffer from fatigue. Biological pathways underlying fatigue are unknown. In this study aptamer-based SOMAscan technology is used to identify potentia
Externí odkaz:
https://doaj.org/article/46734dad477b4401b0089d6c67ed3791