Zobrazeno 1 - 10 of 78 pro vyhledávání: '"P L, Weissberg"'
1
Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis
Autor: David Izquierdo-Garcia, Nichola Figg, J. R. Davies, John C. Clark, Elizabeth A. Warburton, P. L. Weissberg, Joseph L E Bird, Anthony P. Davenport, James H.F. Rudd, Katrin C. Probst
Publikováno v: Atherosclerosis
Macrophage presence within atherosclerotic plaque is a feature of instability and a risk factor for plaque rupture and clinical events. Activated macrophages express high levels of the translocator protein/peripheral benzodiazepine receptor (TSPO/PBR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cd101fdc420c6fbe57a76e5a14a1a4
https://doi.org/10.1016/j.atherosclerosis.2009.11.047
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3
Acetylated Low-Density Lipoprotein Stimulates Human Vascular Smooth Muscle Cell Calcification by Promoting Osteoblastic Differentiation and Inhibiting Phagocytosis
Autor: Diane Proudfoot, Jeremy N. Skepper, John D. Davies, P. L. Weissberg, Catherine M. Shanahan
Publikováno v: Circulation. 106:3044-3050
Background— Vascular smooth muscle cells (VSMCs) in atherosclerotic lesions display an osteogenic phenotype, and calcification commonly occurs in association with lipid. We therefore tested the hypothesis that lipid components in atherosclerotic le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a9eb0cb4d7c77f0bf23fe2c47f74bb
https://doi.org/10.1161/01.cir.0000041429.83465.41
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4
Expression of mineralisation-regulating proteins in association with human vascular calcification
Autor: Nathaniel R.B. Cary, Diane Proudfoot, Kerry L. Tyson, P. L. Weissberg, Catherine M. Shanahan, Michael Edmonds
Publikováno v: Zeitschrift f�r Kardiologie. 89:S063-S068
These studies aim to investigate the expression and function of mineralisation-regulating proteins in association with human vascular calcification focussing on the similarities and differences between the two major calcification pathologies in man:
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93787fcb842d8a34f94cb30f032b6333
https://doi.org/10.1007/s003920070101
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5
HLA antigen frequencies in end-stage idiopathic and ischaemic cardiomyopathy
Autor: S.R. Large, V Joysey, Linda D. Sharples, P L Weissberg, Alun A Harcombe, John Wallwork
Publikováno v: International Journal of Cardiology. 68:31-37
We investigated the distribution of HLA antigens among 413 patients with ischaemic heart disease or dilated cardiomyopathy referred for cardiac transplantation to determine if possession of certain HLA antigens predisposed to end-stage heart failure.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09d6ebce60de55bfef17dec6a24e088
https://doi.org/10.1016/s0167-5273(98)00336-2
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6
Circulating Antibodies to Cardiac Protein—Acetaldehyde Adducts in Alcoholic Heart Muscle Disease
Autor: John Koskinas, P. L. Weissberg, Peter J. Richardson, A Harcombe, J G Kenna, L. Ramsay, H. J. F. Why, GraemeJ.M. Alexander
Publikováno v: Clinical Science. 88:263-268
1. Serum samples from patients with alcoholic heart muscle disease and from control subjects with and without heart disease who did not drink to excess were screened by Western immunoblotting for antibodies to acetaldehyde-modified cardiac cytosolic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a7ef41d52bd572137e2c6351ab417c
https://doi.org/10.1042/cs0880263
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8
Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells
Autor: P. L. Weissberg, J C Metcalfe, Catherine M. Shanahan
Publikováno v: Circulation Research. 73:193-204
To isolate specific markers of both differentiated and proliferating vascular smooth muscle cells (VSMCs), we used the technique of differential cDNA screening using RNA from cultured rat aortic VSMCs. The tissue specificity of expression of all of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126922707e937dce954045ef08856f5c
https://doi.org/10.1161/01.res.73.1.193
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9
Hexamethylenebisacetamide selectively inhibits the proliferation of human and rat vascular smooth-muscle cells
Autor: T R Hesketh, J C Metcalfe, D J Grainger, P. L. Weissberg
Publikováno v: Biochemical Journal. 283:403-408
Hexamethylenebisacetamide (HMBA) selectively and reversibly inhibited proliferation of human and rat vascular smooth-muscle cells (VSMCs) compared with endothelial cells, fibroblasts or lymphocytes. Half-maximal inhibition of VSMC proliferation occur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc88407e58d28093055fc850715e19b
https://doi.org/10.1042/bj2830403
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10
A large accumulation of non-muscle myosin occurs at first entry into M phase in rat vascular smooth-muscle cells
Autor: T R Hesketh, P. L. Weissberg, J C Metcalfe, D J Grainger
Publikováno v: Biochemical Journal. 277:145-151
Vascular smooth-muscle cells (VSMCs) from rat aortae contained very little non-muscle myosin heavy chain (MHC) immediately after dispersal, and the protein did not accumulate if the cells were held in G0/G1 phase by withholding serum or were held in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad8e7f1b6b615594cf5d22793a74c7a
https://doi.org/10.1042/bj2770145
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