Zobrazeno 1 - 10
of 38
pro vyhledávání: '"P L, Skipper"'
Autor:
P. L. Skipper, S. K. Hammond, J. Coghlin, Peter H. Gann, K. Taghizadeh, M. Paul, S. R. Tannenbaum
Publikováno v:
JNCI Journal of the National Cancer Institute. 85:474-478
A potent bladder carcinogen for workers in the dye industry, 4-aminobiphenyl (4-ABP), is present in environmental tobacco smoke and has been shown to bond covalently with hemoglobin.The goal of this study was to examine the relationship between expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e116b5c1c5a826834c957cfd3987b9
https://doi.org/10.1093/jnci/85.6.474
https://doi.org/10.1093/jnci/85.6.474
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(7)
The ubiquitous environmental carcinogen benzo[a]pyrene (BaP) is metabolized in vivo in humans to its ultimate carcinogenic form of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE). Mouse skin tumorigenicity studies indicate that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e612d3064f2fd01619c6658e1bb4d02
https://pubmed.ncbi.nlm.nih.gov/10919745
https://pubmed.ncbi.nlm.nih.gov/10919745
Autor:
N M, Probst-Hensch, D A, Bell, M A, Watson, P L, Skipper, S R, Tannenbaum, K K, Chan, R K, Ross, M C, Yu
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(6)
Aminobiphenyls (ABPs) in tobacco have been implicated in bladder cancer etiology in smokers. N-Acetylation of ABPs in the liver, predominantly by the N-acetyltransferase 2 (NAT2) isozyme, represents a detoxification pathway, whereas O-acetylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::787b9c5c1808a677e782d79cba0419d0
https://pubmed.ncbi.nlm.nih.gov/10868698
https://pubmed.ncbi.nlm.nih.gov/10868698
Autor:
L C, Kidd, W G, Stillwell, M C, Yu, J S, Wishnok, P L, Skipper, R K, Ross, B E, Henderson, S R, Tannenbaum
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 8(5)
Meats, such as beef, pork, poultry, and fish, cooked at high temperatures produce heterocyclic aromatic amines, which have been implicated indirectly as etiological agents involved in colorectal and other cancers in humans. This study examined the ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b64663a14de3eef70be85f73326f0fa8
https://pubmed.ncbi.nlm.nih.gov/10815701
https://pubmed.ncbi.nlm.nih.gov/10815701
Publikováno v:
The Journal of Organic Chemistry. 55:2918-2920
New syntheses of cyclopenta(cd)pyrene 3,4-oxide (CPPE) and 4-pyrenylacetic acid, a key intermediate in the synthesis of cyclopenta(cd)pyrene and CPPE, as described starting from 1,2,3,6,7,8-hexahydropyrene. 4-Pyrenylacetic acid is prepared from the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b549dd63fc15d16aede4d4ee3d2331c
https://doi.org/10.1021/jo00296a065
https://doi.org/10.1021/jo00296a065
Autor:
S R, Tannenbaum, W G, Stillwell, H, Ji, P L, Skipper, M C, Yu, R K, Ross, B E, Henderson, R J, Turesky, G A, Gross
Publikováno v:
Princess Takamatsu symposia. 23
The metabolism of the heterocyclic amines has been extensively studied in rodents and limited studies have been conducted in nonhuman primates. A study has been undertaken on the metabolism of 2-amino-3,8-dimethylimadazo[4,5-f]quinoxaline (MeIQx) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b457f6fe0233669306c8443bee88bd93
https://pubmed.ncbi.nlm.nih.gov/8844811
https://pubmed.ncbi.nlm.nih.gov/8844811
Publikováno v:
Cancer research. 54(21)
The effect of cell replication on histone-carcinogen adducts was investigated by determining the specific adduct levels as a function of time following carcinogen treatment of human TK6 cells grown in culture. Core histones isolated from cells treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29213460828d864e5fca9239498db7d7
https://pubmed.ncbi.nlm.nih.gov/7923203
https://pubmed.ncbi.nlm.nih.gov/7923203
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 3(5)
The heterocyclic aromatic amines produced by high temperature cooking of foods containing creatin(in)e and amino acids (such as beef, pork, poultry and fish) are a class of potent animal carcinogens and have been implicated indirectly in human colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ff42154a1dab7414c49192aa23316ae
https://pubmed.ncbi.nlm.nih.gov/7920208
https://pubmed.ncbi.nlm.nih.gov/7920208
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 3(5)
The contribution of Phase II conjugation reactions to human disposition of 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MelQx) was investigated by analysis of urine for MelQx and its sulfamate and glucuronide metabolites. Subjects consumed pan-fri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b26fe2bd2fdfff501feeff13becee3a3
https://pubmed.ncbi.nlm.nih.gov/7920207
https://pubmed.ncbi.nlm.nih.gov/7920207
Autor:
P L, Skipper, W G, Stillwell
Publikováno v:
Methods in enzymology. 231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b92a0b2012260fa89cbc88e2f4450049
https://pubmed.ncbi.nlm.nih.gov/8041282
https://pubmed.ncbi.nlm.nih.gov/8041282