Zobrazeno 1 - 10
of 13
pro vyhledávání: '"P L, Goering"'
Autor:
James L. Weaver, Grainne A. Tobin, Taylor Ingle, Simona Bancos, David Stevens, Rodney Rouse, Kristina E. Howard, David Goodwin, Alan Knapton, Xiaohong Li, Katherine Shea, Sharron Stewart, Lin Xu, Peter L. Goering, Qin Zhang, Paul C. Howard, Jessie Collins, Saeed Khan, Kidon Sung, Katherine M. Tyner
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-14 (2017)
Abstract Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate
Externí odkaz:
https://doaj.org/article/785283ca27204af9b663b605868fcf5a
Autor:
Alexander K. Nguyen, Peter L. Goering, Rosalie K. Elespuru, Srilekha Sarkar Das, Roger J. Narayan
Publikováno v:
Polymers, Vol 12, Iss 7, p 1489 (2020)
Lithium phenyl (2,4,6-trimethylbenzoyl) phosphinate (LAP) is a free radical photo-initiator used to initiate free radical chain polymerization upon light exposure, and is combined with gelatin methacryloyl (GelMA) to produce a photopolymer used in bi
Externí odkaz:
https://doaj.org/article/d3c0a193473e44608acedcd66c609e37
Autor:
T H, Umbreit, S, Francke-Carroll, J L, Weaver, T J, Miller, P L, Goering, N, Sadrieh, M E, Stratmeyer
Publikováno v:
Journal of applied toxicology : JAT. 32(5)
Nanoparticles can be formed following degradation of medical devices such as orthopedic implants. To evaluate the safety of titanium alloy orthopedic materials, data are needed on the long-term distribution and tissue effects of injected titanium nan
Autor:
P. L. Goering, B. R. Fisher
Publikováno v:
Toxicology of Metals ISBN: 9783642791642
Prokaryotic and eukaryotic cells respond to physical and chemical stressors or stress by increasing the transcription of specific genes that encode for a small class of proteins termed heat shock proteins (hsps). This response is believed to represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e749f287e883eb60edcef5aaa8247772
https://doi.org/10.1007/978-3-642-79162-8_11
https://doi.org/10.1007/978-3-642-79162-8_11
Autor:
P L, Goering
Publikováno v:
Neurotoxicology. 14(2-3)
The interaction of lead (Pb) with proteins may represent a fundamental mechanism by which Pb exerts toxicity. In this overview, various factors which influence the interaction of Pb with proteins will be discussed. Pb interacts with enzyme functional
Autor:
P L Goering, B A Fowler
Publikováno v:
Biochemical Journal. 245:339-345
This study was undertaken to evaluate the effect of Zn and Cd pretreatment on the inhibition of delta-aminolaevulinic acid dehydratase (ALAD; porphobilinogen synthase, EC 4.2.1.24) by Pb. Male CD rats were pretreated with 200 mumol of Zn/kg s.c. (sub
Autor:
P L, Goering, B A, Fowler
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 234(2)
The bioavailability of lead in kidney is mediated in part by binding to endogenous high-affinity cytosolic lead-binding proteins (PbBP), which are not detectable in liver. Addition of semipurified 11,500 dalton PbBP to liver delta-aminolevulinic acid
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 5(5)
Endogenous sulfhydryl compounds serve a critical role in maintaining the function and viability of living systems. Glutathione (GSH) is the most abundant of these nonprotein thiols. During the past decade it has been demonstrated that sulfhydryls suc
Publikováno v:
Experientia. Supplementum. 52
Prolonged cadmium exposure has been associated with proteinuria, calcuria and loss of calcium from bones in humans. Previous studies have shown that kidney uptake of cadmium in vivo results from proximal tubule absorption of the circulating cadmium m
Autor:
P L, Goering, B A, Fowler
Publikováno v:
Experientia. Supplementum. 52
Metallothionein has been postulated to function in essential metal homeostasis. In this study, we demonstrate a 1.7-fold increase in purified bovine liver delta-aminolevulinic acid dehydratase (ALAD) activity following incubation with purified kidney