Zobrazeno 1 - 10
of 14
pro vyhledávání: '"P L, Bonate"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 11, Pp 1824-1829 (2024)
Externí odkaz:
https://doaj.org/article/dfeb96f0c62f4166b414c4864bd5ec5e
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 6, Pp 669-672 (2022)
Externí odkaz:
https://doaj.org/article/cef587722d9649b09e4afcd5c1361126
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 11, Pp 659-669 (2020)
Direct oral anticoagulants, such as apixaban and rivaroxaban, are important for the treatment and prophylaxis of venous thromboembolism and to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Because a
Externí odkaz:
https://doaj.org/article/358db0b58d284733ab7b69cf702b183b
Autor:
P L Bonate
Publikováno v:
Clinical pharmacology and therapeutics. 96(4)
Publikováno v:
Journal of Liquid Chromatography. 18:3473-3494
An HPLC assay using UV detection has been developed for the analysis of cocaine in biological matrices. Samples were precipitated with perchloric acid, extracted in 5% chloroform/pentane at pH 10, and back-extracted into 0.1 N hydrochloric acid. Samp
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 669:397-403
A reversed-phase high-performance liquid chromatographic assay (HPLC) was utilized for monitoring xanomeline (LY246708/NNC 11-0232) and a metabolite, desmethylxanomeline, in human plasma. Xanomeline, desmethylxanomeline and internal standard were ext
Autor:
P L, Bonate, D, Howard
Publikováno v:
Journal of clinical pharmacology. 40(6)
We are not suggesting that an allometric relationship between pharmacokinetic parameters in animals and humans does not exist; we believe that it does. We are suggesting that using prospective AS to select doses in an FTIM study may lead to a false s
Autor:
P L, Bonate
Publikováno v:
Pharmaceutical research. 16(5)
To demonstrate how correlations among predictor variables in a population pharmacokinetic model affect the ability to discern which covariates should enter into the structural pharmacokinetic model.Monte Carlo simulation was used to generate multiple
Autor:
P L, Bonate
Publikováno v:
Pharmaceutical research. 15(3)
The coverage and precision of parametric Bailer-type confidence intervals (CIs) for area under the curve (AUC) was compared to nonparametric bootstrap confidence intervals.Concentration-time data was simulated using Monte Carlo simulation under a tox
Autor:
A. F. DeLong, Theresa G. Skaggs, Todd A. Gillespie, J.David Cornpropst, P. L. Bonate, Lisa A. Shipley, Thomas J. Lindsay
Publikováno v:
ACS Symposium Series ISBN: 9780841233782
Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry
Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc1d03e927ab26233a96aca3632039e
https://doi.org/10.1021/bk-1995-0619.ch016
https://doi.org/10.1021/bk-1995-0619.ch016