Zobrazeno 1 - 10
of 354
pro vyhledávání: '"P K Greer"'
Autor:
J. S. Evans, J. Correira, J. D. Lumpe, R. W. Eastes, Q. Gan, F. I. Laskar, S. Aryal, W. Wang, A. G. Burns, S. Beland, X. Cai, M. Codrescu, S. England, K. Greer, A. Krywonos, W. E. McClintock, T. Plummer, V. Veibell
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 16, Pp n/a-n/a (2024)
Abstract After days of intense solar activity, active region AR3664 launched seven CMEs toward Earth producing an extreme G5 geomagnetic storm commencing at 17:05 UT on 10 May 2024. The storm impacted power grids, disrupted precision navigational sys
Externí odkaz:
https://doaj.org/article/242be7ca30964f1580aa779275e222e4
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Background Aberrations to endoplasmic/sarcoplasmic reticulum (ER/SR) calcium concentration can result in the departure of endogenous proteins in a phenomenon termed exodosis. Redistribution of the ER/SR proteome can have deleterious effects
Externí odkaz:
https://doaj.org/article/fd93747235684bd5a467c03348f87f42
Autor:
Cheng Xu, Heng Liu, Christopher J. Pirozzi, Lee H. Chen, Paula K. Greer, Bill H. Diplas, Liwei Zhang, Matthew S. Waitkus, Yiping He, Hai Yan
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Diffuse intrinsic pontine gliomas (DIPGs) are high-grade tumors of the brainstem that often occur in children, with a median overall survival of less than one year. Given the fact that DIPGs are resistant to chemotherapy and are not amenable
Externí odkaz:
https://doaj.org/article/e93641f3ec424b8eb9474f91fac10d50
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Allied health assistants (AHAs) support allied health professionals (AHPs) to meet workforce demands in modern healthcare systems. Previous studies have indicated that AHAs may be underutilised in some contexts. This study aims to
Externí odkaz:
https://doaj.org/article/28ea15246de84385ab38a547311fbc3b
Autor:
Simranjit X. Singh, Rui Yang, Kristen Roso, Landon J. Hansen, Changzheng Du, Lee H. Chen, Paula K. Greer, Christopher J. Pirozzi, Yiping He
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 751 (2022)
Glioblastoma (GBM) is a lethal brain cancer exhibiting high levels of drug resistance, a feature partially imparted by tumor cell stemness. Recent work shows that homozygous MTAP deletion, a genetic alteration occurring in about half of all GBMs, pro
Externí odkaz:
https://doaj.org/article/a2f34eeb4d164ba6a4ede50903e97f18
Autor:
Bill H. Diplas, Xujun He, Jacqueline A. Brosnan-Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, Patrick J. Killela, Daniel B. Loriaux, Eric S. Lipp, Paula K. Greer, Rui Yang, Anthony J. Rizzo, Fausto J. Rodriguez, Allan H. Friedman, Henry S. Friedman, Sizhen Wang, Yiping He, Roger E. McLendon, Darell D. Bigner, Yuchen Jiao, Matthew S. Waitkus, Alan K. Meeker, Hai Yan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Glioblastoma can be classified based on IDH and TERT promoter mutations, but ~20% of glioblastoma do not have these mutations (TERT p WT-IDH WT glioblastoma). Here, the authors present a genetic landscape of TERTp WT-IDH WT glioblastoma, identifying
Externí odkaz:
https://doaj.org/article/dd48eac540f1490a9bb31a4f740711ca
Autor:
Changzheng Du, Landon J. Hansen, Simranjit X. Singh, Feiyifan Wang, Ran Sun, Casey J. Moure, Kristen Roso, Paula K. Greer, Hai Yan, Yiping He
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3199-3211.e5 (2019)
Summary: H2AX safeguards genomic stability in a dose-dependent manner; however, mechanisms governing its proteostasis are poorly understood. Here, we identify a PRMT5-RNF168-SMURF2 cascade that regulates H2AX proteostasis. We show that PRMT5 sustains
Externí odkaz:
https://doaj.org/article/459387299e6e4c179961106be258eabb
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