Zobrazeno 1 - 10 of 65 pro vyhledávání: '"P K, Wellauer"'
1
The DNA-Binding Activity of Transcription Factor PTF1 Parallels the Synthesis of Pancreas-Specific mRNAs during Mouse Development
Autor: O Hagenbüchle, S Petrucco, P K Wellauer
Publikováno v: Molecular and Cellular Biology. 10:254-264
We have studied the expression of the alpha-amylase, trypsin, and elastase II genes in the acinar pancreas during mouse development. Transcriptional control is the major mechanism by which the differential accumulation of alpha-amylase, trypsin, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49cd675d1208e0246c8eb376d1805e3f
https://doi.org/10.1128/mcb.10.1.254-264.1990
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2
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein
Autor: A, Krapp, M, Knöfler, S, Frutiger, G J, Hughes, O, Hagenbüchle, P K, Wellauer
Publikováno v: The EMBO journal. 15(16)
We report the isolation of cDNA for the p48 DNA-binding subunit of the heterooligomeric transcription factor PTF1. A sequence analysis of the cDNA demonstrates that p48 is a new member of the family of basic helix-loop-helix (bHLH) transcription fact
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a265bf763279ad90d84272022a97c434
https://pubmed.ncbi.nlm.nih.gov/8861960
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3
Identification of a Cell-Specific DNA-Binding Activity That Interacts with a Transcriptional Activator of Genes Expressed in the Acinar Pancreas
Autor: M Cockell, Michel Strubin, O Hagenbüchle, B J Stevenson, P K Wellauer
Publikováno v: Molecular and Cellular Biology. 9:2464-2476
Footprint analysis of the 5'-flanking regions of the alpha-amylase 2, elastase 2, and trypsina genes, which are expressed in the acinar pancreas, showed multiple sites of protein-DNA interaction for each gene. Competition experiments demonstrated tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe751277f1d5c25f2124c30b5de6a39
https://doi.org/10.1128/mcb.9.6.2464-2476.1989
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5
Structure and Tissue-Specific Expression of Members of the Mouse α-Amylase Multigene Family
Autor: Otto Hagenbüchle, Richard A. Young, P. K. Wellauer, U. Schibler, Mario Tosi
Publikováno v: Biochemistry of Differentiation and Morphogenesis ISBN: 9783642688355
One approach to study cell differentiation is to elucidate the molecular mechanisms which govern the expression of tissue-specific genes. Such regulatory mechanisms include rates of transcription, efficiency of RNA processing, mRNA flow rates from nu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::228110dcb2c6618247075c6d7bb049a9
https://doi.org/10.1007/978-3-642-68833-1_2
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7
Regulation of Alpha-Amylase Gene Expression
Autor: Otto Hagenbüchle, Ueli Schibler, P. K. Wellauer, H. C. Hurst, Shaw Ph, D. L. Cribbs
Publikováno v: Coordinated Regulation of Gene Expression ISBN: 9781461293156
The aim of our studies is to elucidate in molecular detail the principles underlying the tissue specific expression of eucaryotic genes. It is hoped that by understanding how a particular gene becomes activated in one (or a few), but not other tissue
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75cc6d1063b89687e342aee3d4e31c82
https://doi.org/10.1007/978-1-4613-2245-0_7
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