Zobrazeno 1 - 10
of 390
pro vyhledávání: '"P K, Chang"'
Autor:
Vincent K. Chang, Marjorie Z. Imperial, Patrick P. J. Phillips, Gustavo E. Velásquez, Payam Nahid, Andrew Vernon, Ekaterina V. Kurbatova, Susan Swindells, Richard E. Chaisson, Susan E. Dorman, John L. Johnson, Marc Weiner, Erin E. Sizemore, William Whitworth, Wendy Carr, Kia E. Bryant, Deron Burton, Kelly E. Dooley, Melissa Engle, Pheona Nsubuga, Andreas H. Diacon, Nguyen Viet Nhung, Rodney Dawson, Radojka M. Savic, AIDS Clinical Trial Group, Tuberculosis Trials Consortium
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The Phase 3 randomized controlled trial, TBTC Study 31/ACTG A5349 (NCT02410772) demonstrated that a 4-month rifapentine-moxifloxacin regimen for drug-susceptible pulmonary tuberculosis was safe and effective. The primary efficacy outcome was
Externí odkaz:
https://doaj.org/article/de940f5d4bbc4e00aaa1dfc2d65e721a
Publikováno v:
AgriEngineering, Vol 6, Iss 3, Pp 3345-3361 (2024)
Precision agriculture (PA) technologies combined with remote sensors, GPS, and GIS are transforming the agricultural industry while promoting sustainable farming practices with the ability to optimize resource utilization and minimize environmental i
Externí odkaz:
https://doaj.org/article/de0aa66d3c7440b790cad23954ca4c10
Autor:
Sean F. Cooke, Thomas A. Wright, Yuan Yan Sin, Jiayue Ling, Elka Kyurkchieva, Nattaporn Phanthaphol, Thomas Mcskimming, Katharine Herbert, Selma Rebus, Andrew V. Biankin, David K. Chang, George S. Baillie, Connor M. Blair
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is considered the third leading cause of cancer mortality in the western world, offering advanced stage patients with few viable treatment options. Consequently, there remains an urgent unmet need to d
Externí odkaz:
https://doaj.org/article/16d4a69d0ef14307a98c84f3b800fbc9
Autor:
Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. I
Externí odkaz:
https://doaj.org/article/3b63169b435447a19a5fb490ee037279
Autor:
Alessandra Pulvirenti, Marialuisa Barbagallo, Anna Rita Putignano, Antonio Pea, Rebecca Polidori, Rosie Upstill-Goddard, Nina Cortese, Paolo Kunderfranco, Laura Brunelli, Giulia De Simone, Roberta Pastorelli, Paola Spaggiari, Gennaro Nappo, Nigel B. Jamieson, Alessandro Zerbi, David K. Chang, Giovanni Capretti, Federica Marchesi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMetabolic reprogramming is a hallmark feature of pancreatic ductal adenocarcinoma (PDAC). A pancreatic juice (PJ) metabolic signature has been reported to be prognostic of oncological outcome for PDAC. Integration of PJ profiling with tra
Externí odkaz:
https://doaj.org/article/a7368bd159a94ff69e5350a5c10d750f
Autor:
Ri K. Chang, Mark S. Okihiro
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Elasmobranchs are common, iconic species in public aquaria; their wild counterparts are key members of marine ecosystems. Post-mortem examination is a critical tool for disease monitoring of wild elasmobranchs and for management of those under human
Externí odkaz:
https://doaj.org/article/0afeb0ba036b48158d9d0fda135d7b71
Autor:
Ri K. Chang, Melissa A. Miller, Hasan C. Tekedar, Divya Rose, Julio C. García, Benjamin R. LaFrentz, Caitlin E. Older, Geoffrey C. Waldbieser, Eric Pomaranski, Khalid Shahin, Alvin C. Camus, Francesca Batac, Barbara A. Byrne, Michael J. Murray, Matt J. Griffin, Esteban Soto
Publikováno v:
Frontiers in Microbiology, Vol 14 (2024)
Erysipelothrix spp., including E. rhusiopathiae, are zoonotic bacterial pathogens that can cause morbidity and mortality in mammals, fish, reptiles, birds, and humans. The southern sea otter (SSO; Enhydra lutris nereis) is a federally-listed threaten
Externí odkaz:
https://doaj.org/article/c6445fea056a44c8b7115dde39604a17
Autor:
Matthew C. L. Phillips, Samuel E. Johnston, Pat Simpson, David K. Chang, Danielle Mather, Rognvald J. Dick
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder. The most devastating variant is bulbar-onset ALS, which portends a median survival of 24 months from the onset of symptoms. Abundant evidence indicates that neuron metabo
Externí odkaz:
https://doaj.org/article/4e88d55051f1487cae4431a13ca018ee
Publikováno v:
AgriEngineering, Vol 5, Iss 2, Pp 886-904 (2023)
Field imagery is an effective way to capture the state of the entire field; yet, current field inspection approaches, when accounting for image resolution and processing speed, using existent imaging systems, do not always enable real-time field insp
Externí odkaz:
https://doaj.org/article/54ffa894355d41b988b1421b513673ae
Autor:
Josh McGovern, Stephen Leadbitter, Gillian Miller, Adam Hounat, Irvine Kamande, Ross D. Dolan, Paul G. Horgan, David K. Chang, Nigel B. Jamieson, Donald C. McMillan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract High vagal nerve activity, reliability measured by HRV, is considered protective in cancer, reducing oxidative stress, inflammation and opposing sympathetic nerve activity. The present monocentric study examines the relationship between HRV,
Externí odkaz:
https://doaj.org/article/0344f688208c4bb4922fe908ca3e567e