Zobrazeno 1 - 10
of 10
pro vyhledávání: '"P J Snoy"'
Autor:
Chen Sun, Hui Fang, Tao Xie, Roger D Auth, Nayana Patel, Patrick R Murray, Philip J Snoy, David M Frucht
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33583 (2012)
A variety of intestinal pathogens have virulence factors that target mitogen activated protein kinase (MAPK) signaling pathways, including Bacillus anthracis. Anthrax lethal toxin (LT) has specific proteolytic activity against the upstream regulators
Externí odkaz:
https://doaj.org/article/44eed92fb969438295f699651cfc50fe
Autor:
P. J. Snoy
Publikováno v:
Veterinary Pathology. 47:774-778
In 2002, the US Food and Drug Administration issued regulations to allow the approval of human drugs and biological products based on animal efficacy studies when human efficacy studies would be unethical or not feasible. These regulations are intend
Autor:
F. Norelli, J. Y. Tai, W D Zollinger, Rino Rappuoli, P. J. Snoy, Carl E. Frasch, P. Costantini, S. J. N. Devi
Publikováno v:
Infection and Immunity. 65:1045-1052
We reported the first use of group B meningococcal conjugate vaccines in a nonhuman primate model (S. J. N. Devi, C. E. Frasch, W. Zollinger, and P. J. Snoy, p. 427-429, in J. S. Evans, S. E. Yost, M. C. J. Maiden, and I. M. Feavers, ed., Proceedings
Postexposure Prevention of Progressive Vaccinia in SCID Mice Treated with Vaccinia Immune Globulin ▿
Autor:
Malgorzata G. Mikolajczyk, Dorothy E. Scott, Jennifer L. Reed, Michael Kennedy, P. J. Snoy, Robert W Fisher, Mike Bray
A recently reported case of progressive vaccinia (PV) in an immunocompromised patient has refocused attention on this condition. Uniformly fatal prior to the licensure of vaccinia immune globulin (VIG) in 1978, PV was still fatal in about half of VIG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63954e3200a117913ee6fc0762654722
https://europepmc.org/articles/PMC3019770/
https://europepmc.org/articles/PMC3019770/
Publikováno v:
Laterality. 9(3)
In this research we examined biological and behavioural correlates of handedness in a subject cohort of 41 free-ranging young female rhesus macaques (Macaca mulatta). Specifically, we examined relationships between handedness and cerebrospinal fluid
Publikováno v:
Infection and immunity. 61(10)
Administration of pertussis toxin (PT) in combination with diphtheria and tetanus toxoids adsorbed (DT vaccine) or with acellular pertussis vaccine adsorbed and diphtheria and tetanus toxoids (APDT) elicits dose- and time-dependent alterations in hep
Administration of diphtheria and tetanus toxoids and pertussis vaccine adsorbed (DTP vaccine) or endotoxin (LPS) resulted in marked alterations in hepatic drug-metabolizing enzymes in endotoxin-responsive (R) and non-endotoxin-responsive (NR) mice. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7648b3f8f7d2978a866f21e904c52ae9
https://europepmc.org/articles/PMC257391/
https://europepmc.org/articles/PMC257391/
Autor:
Myron M. Levine, Karen L. Kotloff, D A Herrington, L. Van de Verg, Samuel B. Formal, P J Snoy, J P Cogan, J W Newland, T L Hale, J C Sadoff
Publikováno v:
Infection and immunity. 60(6)
A live, oral Shigella vaccine, constructed by transfer of the 140-MDa invasiveness plasmid from Shigella flexneri 5 and the chromosomal genes encoding the group- and type-specific O antigen of S. flexneri 2a to Escherichia coli K-12, was tested in hu
Publikováno v:
Microbios. 71(288-289)
The infectivity of different strains of HIV-1 in rabbits was investigated. The HIV-1RF and HIV-1MN inocula induced anti-envelope antibodies detectable by Western blot, and in the case of HIV-1RF, these antibodies were also detectable by ELISA. The pe
Publikováno v:
Israel journal of medical sciences. 23(6)
As far as we know, humans are the only known natural hosts for M. pneumoniae disease. Whereas volunteer studies have provided useful data on the pathogenesis of disease and efficacy of vaccines, experimentally inducing disease in humans raises seriou