Zobrazeno 1 - 10
of 69
pro vyhledávání: '"P J Munson"'
Autor:
Amena Keshawarz, Helena Bui, Roby Joehanes, Jiantao Ma, Chunyu Liu, Tianxiao Huan, Shih-Jen Hwang, Brandon Tejada, Meera Sooda, Paul Courchesne, Peter J. Munson, Cumhur Y. Demirkale, Chen Yao, Nancy L. Heard-Costa, Achilleas N. Pitsillides, Honghuang Lin, Ching-Ti Liu, Yuxuan Wang, Gina M. Peloso, Jessica Lundin, Jeffrey Haessler, Zhaohui Du, Michael Cho, Craig P. Hersh, Peter Castaldi, Laura M. Raffield, Jia Wen, Yun Li, Alexander P. Reiner, Mike Feolo, Nataliya Sharopova, Ramachandran S. Vasan, Dawn L. DeMeo, April P. Carson, Charles Kooperberg, Daniel Levy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Expression quantitative trait methylation (eQTM) analysis identifies DNA CpG sites at which methylation is associated with gene expression. The present study describes an eQTM resource of CpG-transcript pairs derived from whole blood DNA met
Externí odkaz:
https://doaj.org/article/c06dd3b583dc4254b2ae2dc78e88198e
Autor:
Kelly Ugarelli, Justin E. Campbell, O. Kennedy Rhoades, Calvin J. Munson, Andrew H. Altieri, James G. Douglass, Kenneth L. Heck, Valerie J. Paul, Savanna C. Barry, Lindsey Christ, James W. Fourqurean, Thomas K. Frazer, Samantha T. Linhardt, Charles W. Martin, Ashley M. McDonald, Vivienne A. Main, Sarah A. Manuel, Candela Marco-Méndez, Laura K. Reynolds, Alex Rodriguez, Lucia M. Rodriguez Bravo, Yvonne Sawall, Khalil Smith, William L. Wied, Chang Jae Choi, Ulrich Stingl
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Plant microbiomes are known to serve several important functions for their host, and it is therefore important to understand their composition as well as the factors that may influence these microbial communities. The microbiome of Thalassia testudin
Externí odkaz:
https://doaj.org/article/acbaec67e87947f0900e5a2a7da9e136
Autor:
Alena Ivanova, Lukas Badertscher, Gwen O'Driscoll, Joakim Bergman, Euan Gordon, Anders Gunnarsson, Camilla Johansson, Michael J. Munson, Cristiana Spinelli, Sara Torstensson, Liisa Vilén, Andrei Voirel, John Wiseman, Janusz Rak, Niek Dekker, Elisa Lázaro‐Ibáñez
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Efficient and targeted delivery of therapeutic agents remains a bottleneck in modern medicine. Here, biochemical engineering approaches to advance the repurposing of extracellular vesicles (EVs) as drug delivery vehicles are explored. Target
Externí odkaz:
https://doaj.org/article/e1d689279e454812aab0d9be5d04dcd4
Autor:
Chunyu Liu, Roby Joehanes, Jiantao Ma, Yuxuan Wang, Xianbang Sun, Amena Keshawarz, Meera Sooda, Tianxiao Huan, Shih-Jen Hwang, Helena Bui, Brandon Tejada, Peter J. Munson, Cumhur Y. Demirkale, Nancy L. Heard-Costa, Achilleas N. Pitsillides, Gina M. Peloso, Michael Feolo, Nataliya Sharopova, Ramachandran S. Vasan, Daniel Levy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract To create a scientific resource of expression quantitative trail loci (eQTL), we conducted a genome-wide association study (GWAS) using genotypes obtained from whole genome sequencing (WGS) of DNA and gene expression levels from RNA sequenci
Externí odkaz:
https://doaj.org/article/554845551fca43c4b74fe97ec81785c4
Autor:
Jiantao Ma, Roby Joehanes, Chunyu Liu, Amena Keshawarz, Shih-Jen Hwang, Helena Bui, Brandon Tejada, Meera Sooda, Peter J. Munson, Cumhur Y. Demirkale, Paul Courchesne, Nancy L. Heard-Costa, Achilleas N. Pitsillides, Mike Feolo, Nataliya Sharopova, Ramachandran S. Vasan, Tianxiao Huan, Daniel Levy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract DNA methylation commonly occurs at cytosine-phosphate-guanine sites (CpGs) that can serve as biomarkers for many diseases. We analyzed whole genome sequencing data to identify DNA methylation quantitative trait loci (mQTLs) in 4126 Framingha
Externí odkaz:
https://doaj.org/article/92838d3a373842e1a75e6a556cd68d2d
Autor:
Matthew Yoke Wui Ng, Chara Charsou, Ana Lapao, Sakshi Singh, Laura Trachsel-Moncho, Sebastian W. Schultz, Sigve Nakken, Michael J. Munson, Anne Simonsen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The functions of specific lipids in autophagosome biogenesis are not entirely clear. Here, the authors show that the ER protein GRAMD1C, a cholesterol transport protein, suppresses autophagy initiation and has roles in mitochondrial cholesterol homeo
Externí odkaz:
https://doaj.org/article/e7fede4d4b1c4ef589afdf61c6e3f288
Autor:
Jeremy P. Bost, Miina Ojansivu, Michael J. Munson, Emelie Wesén, Audrey Gallud, Dhanu Gupta, Oskar Gustafsson, Osama Saher, Julia Rädler, Stuart G. Higgins, Taavi Lehto, Margaret N. Holme, Anders Dahlén, Ola Engkvist, Per-Erik Strömstedt, Shalini Andersson, C. I. Edvard Smith, Molly M. Stevens, Elin K. Esbjörner, Anna Collén, Samir El Andaloussi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Two new endosomolytic small compounds increase delivery of splice-switching oligonucleotides by interfering with their trafficking to the LAMP1-positive endosomal compartments, inducing endosomal membrane rupture and concurrent oligonucleotide escape
Externí odkaz:
https://doaj.org/article/bc4472827f7c41fd906f49a090bf9ac9
Autor:
Shuan-Hong Zhang, Richard E. Ernst, Tim J. Munson, Junling Pei, Guohui Hu, Jian-Min Liu, Qi-Qi Zhang, Yu-Hang Cai, Yue Zhao
Publikováno v:
Fundamental Research, Vol 2, Iss 1, Pp 84-100 (2022)
Comparisons of large igneous provinces (LIPs) and black shales from different cratons can provide important constraints on Precambrian paleogeographic reconstructions and a better understanding of the environmental effects of large-scale volcanic eve
Externí odkaz:
https://doaj.org/article/19b5c69af47742dc9e0fb87b130d17bf
Autor:
Michael J. Munson, Benan J. Mathai, Matthew Yoke Wui Ng, Laura Trachsel-Moncho, Laura R. de la Ballina, Sebastian W. Schultz, Yahyah Aman, Alf H. Lystad, Sakshi Singh, Sachin Singh, Jørgen Wesche, Evandro F. Fang, Anne Simonsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
The mechanisms involved in programmed or damage-induced removal of mitochondria by mitophagy remain elusive. Here the authors use an siRNA library to screen lipid-binding proteins, and identify the kinases GAK and PRKCD as positive regulators of PRKN
Externí odkaz:
https://doaj.org/article/b12ee5952fc74880a26b3fbe78bc34b0
Autor:
Michael J. Munson, Gwen O’Driscoll, Andreia M. Silva, Elisa Lázaro-Ibáñez, Audrey Gallud, John T. Wilson, Anna Collén, Elin K. Esbjörner, Alan Sabirsh
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Munson et al. develop a high-throughput Galectin-9 reporter based endosomal escape imaging assay to probe correlations between nanoparticle-mediated uptake, endosomal escape frequency, and mRNA translation. By screening various delivery systems, modu
Externí odkaz:
https://doaj.org/article/6d71f1a55da4454e8e456d8390871e01