Zobrazeno 1 - 10
of 85
pro vyhledávání: '"P J Holdsworth"'
Autor:
Sarah J. Holdsworth-Carson, Jessica Chung, Dorothy A. Machalek, Rebecca Li, Byung Kyu Jun, Meaghan J. Griffiths, Molly Churchill, Tristan McCaughey, Debbie Nisbet, Uri Dior, Jacqueline F. Donoghue, Grant W. Montgomery, Charlotte Reddington, Jane E. Girling, Martin Healey, Peter A. W. Rogers
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-35 (2024)
Abstract Background Despite surgical and pharmacological interventions, endometriosis can recur. Reliable information regarding risk of recurrence following a first diagnosis is scant. The aim of this study was to examine clinical and survey data in
Externí odkaz:
https://doaj.org/article/0c6e2bb3effe449fb14bc5a3deacf170
Autor:
Javid Abderezaei, Fargol Rezayaraghi, Aymeric Pionteck, Ya-Chen Chuang, Alejandro Carrasquilla, Gizem Bilgili, Tianyi Ren, Tyson Lam, Tse-An Lu, Miriam Scadeng, Patrick Fillingham, Peter Morgenstern, Michael R. Levitt, Richard G. Ellenbogen, Yang Yang, Samantha J. Holdsworth, Raj Shrivastava, Mehmet Kurt
Publikováno v:
Brain Multiphysics, Vol 7, Iss , Pp 100100- (2024)
Chiari Malformation type 1 (CM-I) is a neurological disorder characterized by morphological defects including excessive cerebellar tonsillar ectopia and associated manifestations. We used 3D amplified MRI on a cohort of healthy and CM-I subjects to i
Externí odkaz:
https://doaj.org/article/12bb9a7f969a454bb36768eefaeb2103
Autor:
Paul Condron, Daniel M. Cornfeld, Miriam Scadeng, Tracy R. Melzer, Gil Newburn, Mark Bydder, Eryn E. Kwon, Joshua P. McGeown, Geoffrey G. Handsfield, Taylor Emsden, Maryam Tayebi, Samantha J. Holdsworth, Graeme M. Bydder
Publikováno v:
Tomography, Vol 10, Iss 7, Pp 983-1013 (2024)
Ultra-high contrast (UHC) MRI describes forms of MRI in which little or no contrast is seen on conventional MRI images but very high contrast is seen with UHC techniques. One of these techniques uses the divided subtracted inversion recovery (dSIR) s
Externí odkaz:
https://doaj.org/article/4c91cd48264f4e6287ca19b2801c8f85
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Pulse wave encephalopathy (PWE) is hypothesised to initiate many forms of dementia, motivating its identification and risk assessment. As candidate pulsatility based biomarkers for PWE, pulsatility index and pulsatility damping have been stu
Externí odkaz:
https://doaj.org/article/e5046a50024348e99e781bdf76118cff
Autor:
W. T. Teh, J. Chung, S. J. Holdsworth-Carson, J. F. Donoghue, M. Healey, H. C. Rees, S. Bittinger, V. Obers, C. Sloggett, R. Kendarsari, J. N. Fung, S. Mortlock, G. W. Montgomery, J. E. Girling, P. A. W. Rogers
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Natural variability in menstrual cycle length, coupled with rapid changes in endometrial gene expression, makes it difficult to accurately define and compare different stages of the endometrial cycle. Here we develop and validate a method fo
Externí odkaz:
https://doaj.org/article/a2da35840d0641fe9d041c330bd803b1
Autor:
Agata Zubrycka, Charlene Dambire, Laura Dalle Carbonare, Gunjan Sharma, Tinne Boeckx, Kamal Swarup, Craig J. Sturrock, Brian S. Atkinson, Ranjan Swarup, Françoise Corbineau, Neil J. Oldham, Michael J. Holdsworth
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Oxygen is a key signalling component of plant biology, and whilst an oxygen-sensing mechanism was previously described in Arabidopsis thaliana, key features of the associated PLANT CYSTEINE OXIDASE (PCO) N-degron pathway and Group VII ETHYLE
Externí odkaz:
https://doaj.org/article/b0a7bf8d1bb84442a4e0ebb138de7089
Autor:
Mayan J. Bedggood, Christi A. Essex, Alice Theadom, Samantha J. Holdsworth, Richard L.M. Faull, Mangor Pedersen
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103647- (2024)
Mild traumatic brain injury (mTBI), often called concussion, is a prevalent condition that can have significant implications for people’s health, functioning and well-being. Current clinical practice relies on self-reported symptoms to guide decisi
Externí odkaz:
https://doaj.org/article/76da5e8f7cce403fb1c771416aeba2e4
Autor:
Gil Newburn, Paul Condron, Eryn E. Kwon, Joshua P. McGeown, Tracy R. Melzer, Mark Bydder, Mark Griffin, Miriam Scadeng, Leigh Potter, Samantha J. Holdsworth, Daniel M. Cornfeld, Graeme M. Bydder
Publikováno v:
Diagnostics, Vol 14, Iss 4, p 418 (2024)
Background: Delayed Post-Hypoxic Leukoencephalopathy (DPHL), or Grinker’s myelinopathy, is a syndrome in which extensive changes are seen in the white matter of the cerebral hemispheres with MRI weeks or months after a hypoxic episode. T2-weighted
Externí odkaz:
https://doaj.org/article/0ab435d846d54459bc61745869a70e73
Autor:
Keisuke Tanaka, Akwasi A. Amoako, Sally Mortlock, Peter A. W. Rogers, Sarah J. Holdsworth-Carson, Jacqueline F. Donoghue, Wan Tinn Teh, Grant W. Montgomery, Brett McKinnon
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Endocannabinoids mediate cellular functions and their activity is controlled by a complex system of enzymes, membrane receptors and transport molecules. Endocannabinoids are present in endometrium, a cyclical regenerative tissue requiring ti
Externí odkaz:
https://doaj.org/article/5a5c6ddae38c4c04bbfc0cef8011d90c
Autor:
Meaghan J. Griffiths, Sarah A. Marshall, Fiona L. Cousins, Lauren R. Alesi, Jordan Higgins, Saranya Giridharan, Urooza C. Sarma, Ellen Menkhorst, Wei Zhou, Alison S. Care, Jacqueline F. Donoghue, Sarah J. Holdsworth-Carson, Peter A.W. Rogers, Evdokia Dimitriadis, Caroline E. Gargett, Sarah A. Robertson, Amy L. Winship, Karla J. Hutt
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
Female cancer survivors are significantly more likely to experience infertility than the general population. It is well established that chemotherapy and radiotherapy can damage the ovary and compromise fertility, yet the ability of cancer treatments
Externí odkaz:
https://doaj.org/article/ee2f5e90ec17471e8dc9f94a729ae7b3