Zobrazeno 1 - 10
of 18
pro vyhledávání: '"P J Boekema"'
Autor:
Merve Sivridaş, Rob H. Creemers, Dennis R. Wong, Paul J. Boekema, Tessa E. H. Römkens, Lennard P. L. Gilissen, Adriaan A. van Bodegraven, Floris C. Loeff, Theo Rispens, Luc J. J. Derijks
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 972 (2023)
There are limited data on therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD) patients treated with vedolizumab (VDZ). Although an exposure–response relation has been demonstrated in the post-induction phase, this relationship is
Externí odkaz:
https://doaj.org/article/935e6f04083545d584795100813406b1
Autor:
Linda E. Franken, Gert T. Oostergetel, Tjaard Pijning, Pranav Puri, Valentina Arkhipova, Egbert J. Boekema, Bert Poolman, Albert Guskov
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
When bacteria enter the stationary growth phase, protein translation is suppressed via the dimerization of 70S ribosomes into inactive complexes. Here the authors provide a structural basis for how the dual domain hibernation promotion factor promote
Externí odkaz:
https://doaj.org/article/399c1c026c834306bf7b09a8915fb0a1
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103584 (2014)
The cyanobacterial NADPH:plastoquinone oxidoreductase complex (NDH-1), that is related to Complex I of eubacteria and mitochondria, plays a pivotal role in respiration as well as in cyclic electron transfer (CET) around PSI and is involved in a uniqu
Externí odkaz:
https://doaj.org/article/aaab817e2b0d44f6a2a39ce073b4b6d4
P592 Effectiveness and safety of thioguanine in thiopurine-naïve Inflammatory Bowel Disease patients
Autor:
F Crouwel, A B Bayoumy, C J J Mulder, J H C Peters, P J Boekema, L J J Derijks, S Y De Boer, P C van de Meeberg, I Ahmad, H J C Buiter, N K de Boer
Publikováno v:
Journal of Crohn's and Colitis. 16:i529-i529
Background Currently thioguanine is considered as off-label rescue therapy for Inflammatory Bowel Disease (IBD) after conventional thiopurine failure. This study aimed to determine the safety, effectiveness and 12-month drug tolerability of thioguani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5c0df39e8340dbdfb1c07f6f67f0114
https://doi.org/10.1093/ecco-jcc/jjab232.718
https://doi.org/10.1093/ecco-jcc/jjab232.718
Autor:
Ewa Król, Sebastiaan P van Kessel, Laura S van Bezouwen, Neeraj Kumar, Egbert J Boekema, Dirk-Jan Scheffers
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43293 (2012)
Bacterial cell division is mediated by a multi-protein machine known as the "divisome", which assembles at the site of cell division. Formation of the divisome starts with the polymerization of the tubulin-like protein FtsZ into a ring, the Z-ring. Z
Externí odkaz:
https://doaj.org/article/365765101f0b44ae98fbf3823010e8d2
Autor:
Samta Jain, Katarzyna B Mościcka, Martine P Bos, Emilia Pachulec, Marc C A Stuart, Wilko Keegstra, Egbert J Boekema, Chris van der Does
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16624 (2011)
Structures of the type IV pili secretin complexes from Neisseria gonorrhoeae and Neisseria meningitidis, embedded in outer membranes were investigated by transmission electron microscopy. Single particle averaging revealed additional domains not obse
Externí odkaz:
https://doaj.org/article/296b391fe7494e0197b75b5c80e022b7
Autor:
Praveen Balabaskaran Nina, Natalya V Dudkina, Lesley A Kane, Jennifer E van Eyk, Egbert J Boekema, Michael W Mather, Akhil B Vaidya
Publikováno v:
PLoS Biology, Vol 8, Iss 7, p e1000418 (2010)
The F-type ATP synthase complex is a rotary nano-motor driven by proton motive force to synthesize ATP. Its F(1) sector catalyzes ATP synthesis, whereas the F(o) sector conducts the protons and provides a stator for the rotary action of the complex.
Externí odkaz:
https://doaj.org/article/bdb33ee44c444093ade0eeb24b111a9c
Autor:
M. E. C. van de Poll, Luc Brunsveld, Luc J J Derijks, E. M. H. Schmitz, Maarten A. C. Broeren, Volkher Scharnhorst, P. J. Boekema, Jan Willem A Straathof, D. C. van Renswouw
Publikováno v:
Alimentary Pharmacology and Therapeutics, 47(3), 356-363. Wiley-Blackwell
SummaryBackground Infliximab biosimilars have become available for treatment of inflammatory bowel disease (IBD). However, data showing long-term safety and effectiveness of biosimilars in IBD patients are limited. Aim To study prospectively the swit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496a1c5eea49ece308996ba530f1cde0
https://doi.org/10.1111/apt.14453
https://doi.org/10.1111/apt.14453
Publikováno v:
Digestive Diseases and Sciences. 46:945-951
Some people attribute dyspeptic symptoms to drinking coffee, suggesting that coffee affects one or more functions of the proximal gastrointestinal tract. In a randomized controlled, cross-over, single-blinded study, the effects of coffee on gastric r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::904e08a4109c98449b62481f4b18fe15
https://doi.org/10.1023/a:1010733222245
https://doi.org/10.1023/a:1010733222245
Publikováno v:
European Journal of Clinical Investigation. 30:129-134
Background The consumption of coffee allegedly induces or aggravates gastrointestinal symptoms. In order to investigate the effect of coffee on gastrointestinal motility we studied the effect of coffee on gastric emptying and oro-caecal transit time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0095bdc584b980dfb2d2b134c6a06783
https://doi.org/10.1046/j.1365-2362.2000.00601.x
https://doi.org/10.1046/j.1365-2362.2000.00601.x