Zobrazeno 1 - 10
of 34
pro vyhledávání: '"P J Beale"'
Autor:
Marijana Bosnjak, Avinash V. Karpe, Thi Thu Hao Van, Despina Kotsanas, Grant A. Jenkin, Samuel P. Costello, Priscilla Johanesen, Robert J. Moore, David J. Beale, Yogitha N. Srikhanta, Enzo A. Palombo, Sarah Larcombe, Dena Lyras
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Hospital-acquired diarrhoea (HAD) is common, and often associated with gut microbiota and metabolome dysbiosis following antibiotic administration. Clostridioides difficile is the most significant antibiotic-associated diarrhoeal (AAD) patho
Externí odkaz:
https://doaj.org/article/171b8fa865cc45d98514b88392cdb5c6
Autor:
Juliana Muller Bark, Avinash V. Karpe, James D. Doecke, Paul Leo, Rosalind L. Jeffree, Benjamin Chua, Bryan W. Day, David J. Beale, Chamindie Punyadeera
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11427-11437 (2023)
Abstract Background Despite aggressive treatment, more than 90% of glioblastoma (GBM) patients experience recurrences. GBM response to therapy is currently assessed by imaging techniques and tissue biopsy. However, difficulties with these methods may
Externí odkaz:
https://doaj.org/article/bf2d3199e1af4d7b9ff4a2375a3e5b34
Autor:
Sarah E. West, Lucy Way, Rhys Archer, Victoria J. Beale, Sam Bland, Henry Burridge, Claudia Castro-Faccetti, Lia Chatzidiakou, Prashant Kumar, Carolanne Vouriot, Natalie Williams, SAMHE Project Consortium
Publikováno v:
Citizen Science: Theory and Practice, Vol 8, Iss 1, Pp 64-64 (2023)
This methods paper describes a new UK-wide citizen science project, the Schools’ Air Quality Monitoring for Health and Education (SAMHE) project, which is exploring indoor air quality (IAQ) in schools. Central to the project is a Web App, where sch
Externí odkaz:
https://doaj.org/article/f889ebc2ed8e48c08e7590809426b683
Publikováno v:
Microorganisms, Vol 11, Iss 7, p 1800 (2023)
Enteric protozoan pathogenic infections significantly contribute to the global burden of gastrointestinal illnesses. Their occurrence is considerable within remote and indigenous communities and regions due to reduced access to clean water and adequa
Externí odkaz:
https://doaj.org/article/4594f1db6c2b40019e669c2453c13730
Autor:
Anupriya Agarwal, Ann Livingstone, Deme J. Karikios, Martin R. Stockler, Philip J. Beale, Rachael L. Morton
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Optimising the care of individuals with cancer without imposing significant financial burden related to their anticancer treatment is becoming increasingly difficult. The American Society of Clinical Oncology (ASCO) has recommende
Externí odkaz:
https://doaj.org/article/80abb7d222664d61bea0a974e17e4228
Autor:
Avinash V. Karpe, Thao V. Nguyen, Rohan M. Shah, Gough G. Au, Alexander J. McAuley, Glenn A. Marsh, Sarah Riddell, Seshadri S. Vasan, David J. Beale
Publikováno v:
Metabolites, Vol 12, Iss 11, p 1151 (2022)
The global threat of COVID-19 has led to an increased use of metabolomics to study SARS-CoV-2 infections in animals and humans. In spite of these efforts, however, understanding the metabolome of SARS-CoV-2 during an infection remains difficult and i
Externí odkaz:
https://doaj.org/article/6204a50a6f2a46a6ad208f02c3029bf5
Autor:
Maxime François, Avinash V. Karpe, Jian-Wei Liu, David J. Beale, Maryam Hor, Jane Hecker, Jeff Faunt, John Maddison, Sally Johns, James D. Doecke, Stephen Rose, Wayne R. Leifert
Publikováno v:
Metabolites, Vol 12, Iss 10, p 949 (2022)
The metabolomic and proteomic basis of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) is poorly understood, and the relationships between systemic abnormalities in metabolism and AD/MCI pathogenesis is unclear. This study compared the
Externí odkaz:
https://doaj.org/article/dd45502df10c47e9b52b92262cbdd972
Autor:
David J. Beale, Thao V. Nguyen, Rohan M. Shah, Andrew Bissett, Akhikun Nahar, Matthew Smith, Viviana Gonzalez-Astudillo, Christoph Braun, Brenda Baddiley, Suzanne Vardy
Publikováno v:
Metabolites, Vol 12, Iss 8, p 747 (2022)
Per-and polyfluoroalkyl substances (PFAS) are a growing concern for humans, wildlife, and more broadly, ecosystem health. Previously, we characterised the microbial and biochemical impact of elevated PFAS on the gut microbiome of freshwater turtles (
Externí odkaz:
https://doaj.org/article/fed9b5cd356d4212857803161894a86d
Publikováno v:
Metabolites, Vol 12, Iss 4, p 302 (2022)
The dual-sugar intestinal permeability test is a commonly used test to assess changes in gut barrier function. However, it does not identify functional changes and the exact mechanism of damage caused by the increased intestinal permeability. This st
Externí odkaz:
https://doaj.org/article/d548aea8971c41cfbe809b31cb00e3cc
Autor:
Avinash V. Karpe, Melanie L. Hutton, Steven J. Mileto, Meagan L. James, Chris Evans, Rohan M. Shah, Amol B. Ghodke, Katie E. Hillyer, Suzanne S. Metcalfe, Jian-Wei Liu, Tom Walsh, Dena Lyras, Enzo A. Palombo, David J. Beale
Publikováno v:
Metabolites, Vol 11, Iss 6, p 380 (2021)
Cryptosporidiosis is a major human health concern globally. Despite well-established methods, misdiagnosis remains common. Our understanding of the cryptosporidiosis biochemical mechanism remains limited, compounding the difficulty of clinical diagno
Externí odkaz:
https://doaj.org/article/d440e1d4863b4a40a4b7ac06b4d87df7