Zobrazeno 1 - 10
of 23
pro vyhledávání: '"P J, Yazaki"'
Autor:
Lindsay Williams, Lin Li, Paul J. Yazaki, Patty Wong, Teresa Hong, Erasmus K. Poku, Susanta Hui, Hemendra Ghimire, John E. Shively, Maciej Kujawski
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Background The potent immune effects of interleukin‐2 (IL‐2) for cancer therapy can be increased by genetic fusion of IL‐2 to the Fc domain of an antibody (IL‐2‐Fc) or tumor targeted by genetic fusion to a whole antibody known as a
Externí odkaz:
https://doaj.org/article/5d59608a2bfc41f3848415e9d3c06ce0
Autor:
Tom A. Bäck, Karin Jennbacken, Malin Hagberg Thulin, Sture Lindegren, Holger Jensen, Tove Olafsen, Paul J. Yazaki, Stig Palm, Per Albertsson, Jan-Erik Damber, Anna M. Wu, Karin Welén
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Purpose Targeted alpha therapy (TAT) is a promising treatment for micrometastatic and minimal residual cancer. We evaluated systemic α-radioimmunotherapy (α-RIT) of metastatic castration-resistant prostate cancer (mCRPC) using the α-parti
Externí odkaz:
https://doaj.org/article/cb79622cfe444d258013759e1047e094
Autor:
Tabassom Mohajershojai, Preeti Jha, Anna Boström, Fredrik Y. Frejd, Paul J. Yazaki, Marika Nestor
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Carcinoembryonic antigen (CEA) is an antigen that is highly expressed in colorectal cancers and widely used as a tumor marker. 131I and 90Y-radiolabeled anti-CEA monoclonal antibodies (mAbs) have previously been assessed for radioimmunotherapy in ear
Externí odkaz:
https://doaj.org/article/4fe414bf2d204697b6e74e4f33eaaeb6
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Targeted immunotherapy of solid cancers with chimeric antigen receptor (CAR) T cells and immunocytokines are attractive options in that they both rely on the specificity of tumor-targeted antibodies. Since carcinoembryonic antigen (CEA) expression in
Externí odkaz:
https://doaj.org/article/e0b208688c5e48b6a310c1ae5b368ae7
Autor:
Ekaterina Mikhaylova, Jamison Brooks, Darren M. Zuro, Farouk Nouizi, Maciej Kujawski, Srideshikan Sargur Madabushi, Jinyi Qi, Mengxi Zhang, Junie Chea, Erasmus K. Poku, Nicole Bowles, Jeffrey Y. C. Wong, John E. Shively, Paul J Yazaki, Gultekin Gulsen, Simon R. Cherry, Susanta K. Hui
Publikováno v:
IEEE Access, Vol 7, Pp 143207-143216 (2019)
Molecular imaging is becoming essential for precision targeted radiation therapy, yet progress is hindered from a lack of integrated imaging and treatment systems. We report the development of a prototype positron emission tomography (PET) scanner in
Externí odkaz:
https://doaj.org/article/2c0540aaf4bd44a48e2b7ed5b73c5749
Autor:
Michael A. Turner, Thinzar M. Lwin, Siamak Amirfakhri, Hiroto Nishino, Robert M. Hoffman, Paul J. Yazaki, Michael Bouvet
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1819 (2021)
A major barrier to the diagnosis and effective treatment of solid-tumor cancers is the difficulty in detection and visualization of tumor margins in primary and metastatic disease. The use of fluorescence can augment the surgeon’s ability to detect
Externí odkaz:
https://doaj.org/article/b484615bd8594fab9537b7e3920a5ed9
Autor:
Richard T Frank, Marissa Edmiston, Stephen E Kendall, Joseph Najbauer, Chia-Wei Cheung, Thewodros Kassa, Marianne Z Metz, Seung U Kim, Carlotta A Glackin, Anna M Wu, Paul J Yazaki, Karen S Aboody
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8314 (2009)
BACKGROUND: Recombinant monoclonal antibodies have emerged as important tools for cancer therapy. Despite the promise shown by antibody-based therapies, the large molecular size of antibodies limits their ability to efficiently penetrate solid tumors
Externí odkaz:
https://doaj.org/article/3159f93b5aa04d759d7b2560ec324484
Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 17, Iss 4, Pp 433-437 (1976)
A two dimensional thin-layer chromatography system has been devised for the improved separation of phosphatidylglycerol and its derivatives, cardiolipin and bis(monoacylglyceryl)phosphate, from the other phospholipid components of tissue total lipid
Externí odkaz:
https://doaj.org/article/8ac1a7a47dc14918a47eac346395f65f
Autor:
K Y Hostetler, P J Yazaki
Publikováno v:
Journal of Lipid Research, Vol 20, Iss 4, Pp 456-463 (1979)
The subcellular distribution of neutral sphingomyelinase activity has been determined in rat liver. Neutral sphingomyelinase is present in the plasma membrane. This enzyme requires either Mg2+ or Mn2+ for full activity; these cations cannot be replac
Externí odkaz:
https://doaj.org/article/d9a4403f9dfc4b6dae2bade323c7aa6a