Zobrazeno 1 - 10
of 14
pro vyhledávání: '"P J, Weina"'
Publikováno v:
Current Research in Toxicology, Vol 2, Iss , Pp 217-224 (2021)
Objective: To evaluate drug-drug interactions (DDIs) between gefitinib or erlotinib with fluoxetine, and/or losartan. Methods: Human pooled microsomes, supersomes, and cryopreserved human hepatocytes were used to monitor DDIs in vitro. RED (Rapid Equ
Externí odkaz:
https://doaj.org/article/e9c478b36b7c43619dfcb682f88c1248
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 3, Iss , Pp 100112- (2022)
Objective: To evaluate drug-drug interactions (DDIs) between gefitinib with/without losartan and selective serotonin reuptake inhibitors (SSRIs). Methods: In vitro supersomes were used to identify CYP isoenzymes (CYP1A2, 2C9, 2C19, 2D6, and 3A4) invo
Externí odkaz:
https://doaj.org/article/9cb09778310a4cdd9310dcab733c4e90
Autor:
Néstor Sosa, Juan Miguel Pascale, Ana I Jiménez, Jeanne A Norwood, Mara Kreishman-Detrick, Peter J Weina, Kendra Lawrence, William F McCarthy, Ryan C Adams, Charles Scott, Janet Ransom, Douglas Tang, Max Grogl
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007253 (2019)
BackgroundParomomycin-based topical treatments were shown to be effective in curing cutaneous leishmaniasis (CL) lesions caused by Leishmania major in Tunisia. Cure rates of an index lesion were approximately 80%. As a follow on, we conducted a simil
Externí odkaz:
https://doaj.org/article/ca0684b07e454f37bb57db2c769761f0
Autor:
Victor Meléndez, Peter J. Weina, Mark M. Fukuda, Srisombat Wannaying, Robert S. Miller, David Saunders, Apassorn Lim, Nitima Chanarat, Roongnapa Apinan, Paktiya Teja-Isavadharm, Duangsuda Siriyanonda, Raveewan Siripokasupkul
Publikováno v:
Molecules, Vol 15, Iss 12, Pp 8747-8768 (2010)
Artesunate (AS) is a potent antimalarial that is used worldwide for the treatment of malaria. A simple method with a total run time of 12 min was developed and validated for the quantification of AS and dihydroartemisinin (DHA), its active metabolite
Externí odkaz:
https://doaj.org/article/c7de18fe3bb64348904b4d7f9571f87e
Autor:
Qigui Li, Peter J. Weina
Publikováno v:
Molecules, Vol 15, Iss 1, Pp 40-57 (2009)
Preclinical studies in rodents have demonstrated that artemisinins, especially injectable artesunate, can induce fetal death and congenital malformations at a low dose range. The embryotoxicity can be induced in those animals only within a narrow win
Externí odkaz:
https://doaj.org/article/bb3b9bfbbb014e2c986ef5a61358e9e4
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2448 (2013)
Externí odkaz:
https://doaj.org/article/d094f32c92f7497698100c83fddea358
Autor:
Raymond T. Damian, Miguel A. de la Rosa, Daniel J. Murfin, Clarence A. Rawlings, Peter J. Weina, Yang Ping Xue
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 87, Pp 261-269 (1992)
Baboons develop a syndrome, including eosinophilia and transient fever, after infection with carcariae of Schistosoma mansoni that is consistent with the human syndrome of acute schistosomiasis. Radiotelemetry can be used to follow the course of feve
Externí odkaz:
https://doaj.org/article/1c3216ee1c8543b1a694ba6b71744c81
Autor:
Lisa J. Cardo, Ronald Harman, Juan Mendez, W. Melvin, P. J. Weina, L. Ketchum, Francisco J. Rentas, Heather L. Reddy, Raymond P. Goodrich, Jeanne Salata
Publikováno v:
Vox Sanguinis. 90:85-91
Background and Objectives Leishmania is transmitted by the bite of the phlebotomine sandfly or by transfusion of infected blood products. Leishmaniasis currently poses a significant problem in several parts of the world, and is an emerging problem in
From atabrine in World War II to mefloquine in Somalia: the role of education in preventive medicine
Autor:
P J, Weina
Publikováno v:
Military medicine. 163(9)
Preventive medicine requires an understanding not only of the disease to be prevented, but a complete understanding of conditions affecting the disease transmission, human nature, and the historic situation of the target group. An analysis of a new d
Publikováno v:
Laboratory animal science. 45(2)
Variation in the duration of surgical anesthesia in mice prompted an evaluation of various commonly used anesthetics. Using biotelemetric technology, we evaluated the effects of six anesthetic regimens (tribromoethanol, ketamine and acetylpromazine i