Zobrazeno 1 - 10
of 35
pro vyhledávání: '"P J, Stout"'
Autor:
S. Hodge, A. Lee, S. Ruas, R. Rotchés-Ribalta, K.A. Ahmed, S. Maher, M. Larkin, J. Stout, J. Moran, M. Gormally, D. Ó hUallacháin, B. White
Publikováno v:
Irish Journal of Agricultural and Food Research, Vol 63, Iss 1, Pp 66-75 (2024)
Ecologically functioning soils are increasingly viewed as a key component of sustainable agriculture, a means of sequestering carbon and a major contributor to farmland biodiversity. It is generally considered that intensively managed agricultural sy
Externí odkaz:
https://doaj.org/article/3972b198268b4e8eb3332809c2886498
Autor:
Yiming Shi, Lili Liu, Jun Chen, Kristine M. Wylie, Todd N. Wylie, Molly J. Stout, Chan Wang, Haixiang Zhang, Ya-Chen T. Shih, Xiaoyi Xu, Ai Zhang, Sung Hee Park, Hongmei Jiang, Lei Liu
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
The complex nature of microbiome data has made the differential abundance analysis challenging. Microbiome abundance counts are often skewed to the right and heteroscedastic (also known as overdispersion), potentially leading to incorrect inferences
Externí odkaz:
https://doaj.org/article/f9510e9dbaac45348e81969a59661a35
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110877- (2024)
Summary: Cultivated meat has the potential to revolutionize food production, but its progress is hindered by fundamental shortcomings of mammalian cells with respect to industrial-scale bioprocesses. Here, we discuss the essential role of cell line e
Externí odkaz:
https://doaj.org/article/91a3b1b43bd540739d2317a4a5fdac26
Publikováno v:
eLife, Vol 12 (2024)
Functional interactions between the prefrontal cortex and hippocampus, as revealed by strong oscillatory synchronization in the theta (6–11 Hz) frequency range, correlate with memory-guided decision-making. However, the degree to which this form of
Externí odkaz:
https://doaj.org/article/59f2d86677654a6b86b9c2b4df1474bf
Autor:
Jessica W. Chen, William Jacot, Javier Cortés, Ian E. Krop, Susan Dent, Nadia Harbeck, Michelino De Laurentiis, Véronique Diéras, Young‐Hyuck Im, Thomas J. Stout, Frauke Schimmoller, Heidi M. Savage, Katherine E. Hutchinson, Timothy R. Wilson
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2000-2016 (2023)
Taselisib is a potent β‐sparing phosphatidylinositol 3‐kinase (PI3K) inhibitor that, with endocrine therapy, improves outcomes in phosphatidylinositol‐4,5‐bisphosphate 3‐kinase catalytic subunit alpha (PIK3CA)‐mutated (PIK3CAmut) advance
Externí odkaz:
https://doaj.org/article/535a6a7921404a8298c1f95b55637007
Autor:
Bronwyn S. Bedrick, Caroline Cary, Carly O'Donnell, Christine Marx, Hayley Friedman, Ebony B. Carter, Nandini Raghuraman, Molly J. Stout, Benson S. Ku, Kevin Y Xu, Jeannie C. Kelly
Publikováno v:
Drug and Alcohol Dependence Reports, Vol 10, Iss , Pp 100218- (2024)
Background: Amid rising rates of neonatal opioid withdrawal syndrome (NOWS) worldwide and in many regions of the USA, we conducted an audit study (“secret shopper study”) to evaluate the influence of county-level buprenorphine capacity and rurali
Externí odkaz:
https://doaj.org/article/92eede34735d49cbb72e5be0b4f83da0
Engineered autocrine signaling eliminates muscle cell FGF2 requirements for cultured meat production
Autor:
Andrew J. Stout, Xiaoli Zhang, Sophia M. Letcher, Miriam L. Rittenberg, Michelle Shub, Kristin M. Chai, Maya Kaul, David L. Kaplan
Publikováno v:
Cell Reports Sustainability, Vol 1, Iss 1, Pp 100009- (2024)
Summary: Cultivated meat (also known as cultured meat) is a promising technology that faces substantial cost barriers, which are currently driven by the price of media components. Particularly, growth factors such as fibroblast growth factor 2 (FGF2)
Externí odkaz:
https://doaj.org/article/7db4b25dd4fd4cd982ba5c70b1f80d7f
Autor:
Katherine E. Hutchinson, Jessica W. Chen, Heidi M. Savage, Thomas J. Stout, Frauke Schimmoller, Javier Cortés, Susan Dent, Nadia Harbeck, William Jacot, Ian Krop, Sally E. Trabucco, Smruthy Sivakumar, Ethan S. Sokol, Timothy R. Wilson
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Mutations in the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K), encoded by the PIK3CA gene, cause dysregulation of the PI3K pathway in 35–40% of patients with HR+/HER2– breast cancer. Preclinically, cancer c
Externí odkaz:
https://doaj.org/article/6a84c1824dfc43c99cd063f56d446e86
Autor:
Rocky Diegmiller, Laurent Salphati, Bruno Alicke, Timothy R. Wilson, Thomas J. Stout, Marc Hafner
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 9, Pp 1183-1193 (2022)
Abstract A major challenge in oncology drug development is to elucidate why drugs that show promising results in cancer cell lines in vitro fail in mouse studies or human trials. One of the fundamental steps toward solving this problem is to better p
Externí odkaz:
https://doaj.org/article/a27b16f4e3af4e099d40f81f20515d08
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract When faced with difficult choices, the possible outcomes are considered through a process known as deliberation. In rats, deliberation is thought to be reflected by pause-and-reorienting behaviors, better known as vicarious trial and errors
Externí odkaz:
https://doaj.org/article/855f28290b8f4fea8a7e80dd9455b513