Zobrazeno 1 - 10
of 95
pro vyhledávání: '"P J, Sadler"'
Autor:
James D. Shipp, Ricardo J. Fernández-Terán, Alexander J. Auty, Heather Carson, Andrew J. Sadler, Michael Towrie, Igor V. Sazanovich, Paul M. Donaldson, Anthony J. H. M. Meijer, Julia A. Weinstein
Publikováno v:
ACS Physical Chemistry Au, Vol 4, Iss 6, Pp 761-772 (2024)
Externí odkaz:
https://doaj.org/article/efab47761d2a42599581af483dfe5f89
Autor:
Jake Brooks, James Everett, Emily Hill, Kharmen Billimoria, Christopher M. Morris, Peter J. Sadler, Neil Telling, Joanna F. Collingwood
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-7 (2024)
Abstract Neuromelanin-pigmented neurons of the substantia nigra are selectively lost during the progression of Parkinson’s disease. These neurons accumulate iron in the disease state, and iron-mediated neuron damage is implicated in cell death. Ani
Externí odkaz:
https://doaj.org/article/63afa146f787477b8ee42d09a8905646
Autor:
Eva Mendes Serrao, Ana Maria Costa, Sergio Ferreira, Victoria McMorran, Emma Cargill, Caroline Hough, Ashley S. Shaw, Brent O’Carrigan, Christine A. Parkinson, Pippa G. Corrie, Timothy J. Sadler
Publikováno v:
Insights into Imaging, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Melanoma is the most aggressive form of skin cancer, with tendency to spread to any organ of the human body, including the gastrointestinal tract (GIT). The diagnosis of metastases to the GIT can be difficult, as they may be clinically silen
Externí odkaz:
https://doaj.org/article/6a60e48f84134a0a99539f6713a32b90
Publikováno v:
JMIR Medical Education, Vol 9, p e48978 (2023)
BackgroundChatGPT is a large language model that has performed well on professional examinations in the fields of medicine, law, and business. However, it is unclear how ChatGPT would perform on an examination assessing professionalism and situationa
Externí odkaz:
https://doaj.org/article/24ef0964cca04c33ae04e8175db6069f
Autor:
Lei Zhang, Li Jiang, Liang Yu, Qin Li, Xiangjun Tian, Jingquan He, Ling Zeng, Yuqin Yang, Chaoran Wang, Yuhan Wei, Xiaoyue Jiang, Jing Li, Xiaolu Ge, Qisheng Gu, Jikun Li, Di Wu, Anthony J. Sadler, Di Yu, Dakang Xu, Yue Gao, Xiangliang Yuan, Baokun He
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The metabolic environment of tumours has wide-ranging effects on the anti-tumour immune response and the outcome of immune therapy. Authors show here that the purine metabolite inosine enhances tumour immunogenicity and thus immune checkpoint blockad
Externí odkaz:
https://doaj.org/article/852722dd37b04979b5df24d84b26d42c
Autor:
Eva Mendes Serrao, Emily Joslin, Victoria McMorran, Caroline Hough, Cheryl Palmer, Sarah McDonald, Emma Cargill, Ashley S. Shaw, Brent O’Carrigan, Christine A. Parkinson, Pippa G. Corrie, Timothy J. Sadler
Publikováno v:
Cancer Imaging, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Melanoma is the most aggressive form of skin cancer, with a tendency to metastasise to any organ of the human body. While the most common body organs affected include liver, lungs, brain and soft tissues, spread to the gastrointes
Externí odkaz:
https://doaj.org/article/04d6c65cbfa545bebd5fceaa73042eb7
Publikováno v:
Insights into Imaging, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Tuberculosis remains a major global health issue affecting all countries and age groups. Radiology plays a crucial role in the diagnosis and management of pulmonary tuberculosis (PTB). This review aims to improve understanding and diagnostic
Externí odkaz:
https://doaj.org/article/c9cd9321e35c4b009c7dc797ac1876ac
Autor:
Howard Chi Ho Yim, Arindam Chakrabarti, Sean Kessler, Hiroyuki Morimoto, Die Wang, Dhanya Sooraj, Afsar U. Ahmed, Carol de la Motte, Robert H. Silverman, Bryan RG. Williams, Anthony J. Sadler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Here we investigate the function of the innate immune molecule protein kinase R (PKR) in intestinal inflammation. To model a colitogenic role of PKR, we determine the physiological response to dextran sulfate sodium (DSS) of wild-type and two transge
Externí odkaz:
https://doaj.org/article/3eaa421f4b174f7085dd5a670e77412a
Autor:
Luiz G. F. Lopes, Peter J. Sadler, Vânia Bernardes-Génisson, José J. G. Moura, Remi Chauvin, Paul V. Bernhardt, Eduardo H. S. Sousa
Publikováno v:
Química Nova, Vol 43, Iss 8, Pp 1176-1189 (2020)
During the last 150 years or more, society has witnessed many key scientific discoveries and inventions, which have dramatically improved not only our quality of life, but our lifespan. However, the motivation of scientists to provide scientific adva
Externí odkaz:
https://doaj.org/article/769d08b0755945cfa9113712b07f7dd7
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp S134- (2021)
Externí odkaz:
https://doaj.org/article/30a1e2196d55445ea95a46862d5323ca