Zobrazeno 1 - 10
of 73
pro vyhledávání: '"P J, Riekkinen"'
Publikováno v:
Brain Research. 625:93-99
Sustained electrical stimulation of the perforant pathway (PP) was used to induce hippocampal seizures in conscious rats. About 4.5 h prior to stimulation, animals were given i.p. injections of either saline or CGP 39551 (10 mg/kg), a competitive ant
Publikováno v:
Journal of Neural Transmission - Parkinson's Disease and Dementia Section. 6:189-197
L-Deprenyl, a specific MAO-B inhibitor, has been reported to improve learning/memory in some cognitive tests in aged rats. The present study investigated whether L-deprenyl could alleviate the spatial learning deficit induced by muscarinic blockade a
Publikováno v:
Epilepsy Research. 15:221-227
The present experiments were performed to investigate the effects of single and repeated administration of vigabatrin (γ-vinyl-GABA), a novel antiepileptic drug, on a working memory task (delayed non-matching to position task) in non-epileptic rats.
Publikováno v:
Experimental Neurology. 121:193-199
Subcortical deafferentation of the rat hippocampus has been suggested to offer a model for developing limbic epilepsy. In the present study, the long-term effect of fimbria-fornix lesioning on the density and distribution of hippocampal N-methyl-D-as
Autor:
Eeva-Liisa Helkala, Juhani Partanen, Kari Alhainen, Esa Mervaala, M Väyrynen, Veikko Jousmäki, P. J. Riekkinen, Esa Heinonen
Publikováno v:
Behavioural Brain Research. 55:85-91
We studied the electrophysiological and neuropsychological effects of acute modulation of central noradrenergic (NA) transmission using a specific alpha 2-antagonist atipamezole (ATI) in sic healthy volunteers. ATI had effects on resting EEG, auditor
Publikováno v:
General Pharmacology: The Vascular System. 24:675-679
1. The present study investigated the effects of tacrine (an inhibitor of acetylcholinesterase) and zacopride (the antagonist of 5-HT3 receptors) on the performance of adult rats in a continuous operant delayed non-matching to position task assessing
Autor:
Markus Kaski, Päivi Hartikainen, S. Majuri, Eeva-Liisa Helkala, Juhani Partanen, Matti Vanhanen, H. Soininen, P. J. Riekkinen, V. Jousma¨ki
Publikováno v:
Neuroscience. 53:57-63
We studied quantitative electroencephalogram and neuropsychological performance in an aging series of 31 patients with Down's syndrome and compared the findings with those of 36 patients with probable Alzheimer's disease and age-matched controls. We
Autor:
P. J. Riekkinen, Hannu Koponen
Publikováno v:
Psychological Medicine. 23:103-109
SynopsisSeventy consecutive elderly patients meeting the DSM-III criteria for non-alcohol delirium were examined during the acute stage and followed to four years later. The mean age of the patients at the beginning of the index admission was 74, 8±
Publikováno v:
Nordic Journal of Psychiatry. 47:245-249
Depression is the commonest psychiatric reaction after a stroke. It has been suggested that poststroke depression should be taken into account in clinical practice because of its potentially negative impact on the quality of life after a stroke, on t