Zobrazeno 1 - 10
of 643
pro vyhledávání: '"P J, O'Brien"'
Autor:
Michael J. Vasey, Xin You Tai, Jennifer Thorpe, Gabriel Davis Jones, Samantha Ashby, Asma Hallab, Ding Ding, Maria Andraus, Patricia Dugan, Piero Perucca, Daniel J. Costello, Jacqueline A. French, Terence J. O'Brien, Chantal Depondt, Danielle M. Andrade, Robin Sengupta, Ashis Datta, Norman Delanty, Nathalie Jette, Charles R. Newton, Martin J. Brodie, Orrin Devinsky, J. Helen Cross, Josemir W. Sander, Jane Hanna, Frank M. C. Besag, Arjune Sen, the COVID‐19 Epilepsy COV‐E Study Group
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1931-1947 (2024)
Abstract Objective To characterize the experience of people with epilepsy and aligned healthcare workers (HCWs) during the first 18 months of the COVID‐19 pandemic and compare experiences in high‐income countries (HICs) with non‐HICs. Methods S
Externí odkaz:
https://doaj.org/article/24a2a7f5feb64fd0b32ae6a32791a1ab
Autor:
Carmela Cosentino, Said Al Maawali, Thanomporn Wittayacharoenpong, Tracie Tan, Hue Mun Au Yong, Lubna Shakhatreh, Zhibin Chen, Paul Beech, Emma Foster, Terence J. O'Brien, Patrick Kwan, Andrew Neal
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1685-1696 (2024)
Abstract Objectives To determine predictors of successful ictal single photon emission computed tomography (SPECT) injections during Epilepsy Monitoring Unit (EMU) admissions for patients undergoing presurgical evaluation for drug‐resistant focal e
Externí odkaz:
https://doaj.org/article/a48030d77fd747ecb1e46e807efd7380
Autor:
Pablo M. Casillas‐Espinosa, Jennie Garcia‐Olivares, Rui Li, Crystal Li, Chungping Yu, Andrea E. Formella, Terence J. O'Brien
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1826-1836 (2024)
Abstract Objective We evaluated huperzine A treatment in the Genetic Absence Epilepsy Rat from Strasbourg (GAERS) model of genetic generalized epilepsy (GGE) with absence seizures. Methods Adult male GAERS (N = 15) were implanted with EEG recording e
Externí odkaz:
https://doaj.org/article/bcf50cc9ba54439390cd3c38753f2c5f
Autor:
Patrick Kwan, Massimiliano Boffini, Firas Fahoum, Riëm El Tahry, Terence J. O'Brien, Karen Keough, Jane Boggs, Hadassa Goldberg‐Stern, Francesca Beraldi, Gaia Giannicola, Ying‐Chieh Lee, Arjune Sen, CORE‐VNS Registry Group
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1837-1846 (2024)
Abstract Objective Vagus nerve stimulation (VNS) Therapy is routinely indicated for people with drug‐resistant epilepsy (DRE). We analyzed the baseline characteristics of individuals receiving the recently released VNS models and identified factors
Externí odkaz:
https://doaj.org/article/e7d5fcdc67014b58802e736e89bd0046
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Cluster randomized trials (CRTs) are randomized trials where randomization takes place at an administrative level (e.g., hospitals, clinics, or schools) rather than at the individual level. When the number of available clusters is
Externí odkaz:
https://doaj.org/article/cc5cb3befdce40c89666a71968c25962
Autor:
Zhibin Chen, Joshua Laing, Jian Li, Terence J. O'Brien, Belinda J. Gabbe, Bridgette D. Semple
Publikováno v:
Epilepsia Open, Vol 9, Iss 4, Pp 1333-1344 (2024)
Abstract Objective Hospital‐acquired infections are a common complication for patients with moderate or severe traumatic brain injury (TBI), contributing to morbidity and mortality. As infection‐mediated immune responses can predispose towards ep
Externí odkaz:
https://doaj.org/article/c627fd5d620645bb8151e0421fe0ee5b
Autor:
Mohit Javalgekar, Bianca Jupp, Lucy Vivash, Terence J. O’Brien, David K. Wright, Nigel C. Jones, Idrish Ali
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Post-traumatic epilepsy (PTE) is one of the most debilitating consequences of traumatic brain injury (TBI) and is one of the most drug-resistant forms of epilepsy. Novel therapeutic treatment options are an urgent unmet clinical need. The cu
Externí odkaz:
https://doaj.org/article/298b2c2ffd18480d9b0f4ca1d5b70ca0
Autor:
Karen L. Oliver, Ingrid E. Scheffer, Colin A. Ellis, Bronwyn E. Grinton, Samuel F. Berkovic, Melanie Bahlo, Zaid Afawi, Dina Amrom, Eva Andermann, Jocelyn F. Bautista, Susannah T. Bellows, Judith Bluvstein, Gregory D. Cascino, Seo-Kyung Chung, Patrick Cossette, Sarah W. Curtis, Norman Delanty, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Catharine Freyer, Micheline Gravel, Rebekah V. Harris, Erin L. Heinzen, Olivia J. Henry, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rebecca Loeb, Daniel H. Lowenstein, Anthony G. Marson, Heather C. Mefford, Paul V. Motika, Terence J. O'Brien, Ruth Ottman, Juliann M. Paolicchi, Slave Petrovski, William O. Pickrell, Mark I. Rees, Lynette G. Sadleir, Jerry J. Shih, Rani K. Singh, Michael C. Smith, Philip E.M. Smith, Rhys H. Thomas, Judith Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105404- (2024)
Summary: Background: Phenotypic variability within families with epilepsy is often observed, even when relatives share the same monogenic cause. We aimed to investigate whether common polygenic risk for epilepsy could explain the penetrance and pheno
Externí odkaz:
https://doaj.org/article/0d0f5424442d4240b5c116f34ead7cf1
Autor:
Ngoc Vu, Tobias M. Maile, Sudha Gollapudi, Aleksandr Gaun, Phillip Seitzer, Jonathon J. O’Brien, Sean R. Hackett, Jose Zavala-Solorio, Fiona E. McAllister, Ganesh Kolumam, Rob Keyser, Bryson D. Bennett
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100607- (2024)
Blood plasma is one of the most commonly analyzed and easily accessible biological samples. Here, we describe an automated liquid-liquid extraction platform that generates accurate, precise, and reproducible samples for metabolomic, lipidomic, and pr
Externí odkaz:
https://doaj.org/article/4c2c7606b1f34ce2a12d36d49f908b45
Autor:
Liyen K. Kan, Matthew Drill, Padmakrishnan C. Jayakrishnan, Richard P. Sequeira, Paul G. Sanfilippo, Catriona McLean, Martin Hunn, David A. Williams, Terence J. O’Brien, Katharine J. Drummond, Mastura Monif
Publikováno v:
Brain Research Bulletin, Vol 215, Iss , Pp 110996- (2024)
Glioblastoma is the most aggressive and lethal primary brain malignancy with limited treatment options and poor prognosis. Self-renewing glioblastoma cancer stem cells (GSCs) facilitate tumour progression, resistance to conventional treatment and tum
Externí odkaz:
https://doaj.org/article/80c25d4e7f0641f28fbcc87ee26d02d4