Zobrazeno 1 - 10
of 137
pro vyhledávání: '"P J, Neuvonen"'
Autor:
Sajan C. Raju, Heli Viljakainen, Rejane A. O. Figueiredo, Pertti J. Neuvonen, Johan G. Eriksson, Elisabete Weiderpass, Trine B. Rounge
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background The human microbiota contributes to health and well-being. Antimicrobials (AM) have an immediate effect on microbial diversity and composition in the gut, but next to nothing is known about their long-term contribution to saliva m
Externí odkaz:
https://doaj.org/article/87cda85d7dc2485c935c00cda43f9ddf
Autor:
Tuija Tapaninen, Aleksi M. Olkkola, Aleksi Tornio, Mikko Neuvonen, Erkki Elonen, Pertti J. Neuvonen, Mikko Niemi, Janne T. Backman
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 345-351 (2020)
The oral bioavailability of ibrutinib is low and variable, mainly due to extensive first‐pass metabolism by cytochrome P450 (CYP) 3A4. The unpredictable exposure can compromise its safe and effective dosing. We examined the impact of itraconazole o
Externí odkaz:
https://doaj.org/article/701e1cf86da34400937cd534eb0f5ba8
Autor:
Juha Puustinen, Ritva Lähteenmäki, Janne Nurminen, Tero Vahlberg, Pertti Aarnio, Markku Partinen, Ismo Räihä, Pertti J. Neuvonen, Sirkka-Liisa Kivelä
Publikováno v:
BMC Geriatrics, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Studies on persistence of benzodiazepine agonist (BZDA) withdrawal in older outpatients are few, and few studies on long-term persistence over years have yet been published. To describe the persistence of temazepam, zolpidem, and
Externí odkaz:
https://doaj.org/article/c658528ea5cd47b6887714fe0224537d
Autor:
Arja Helin-Salmivaara, Maarit J Korhonen, Petri Lehenkari, Seppo Y T Junnila, Pertti J Neuvonen, Päivi Ruokoniemi, Risto Huupponen
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48095 (2012)
OBJECTIVE: To study the association of long-term statin use and the risk of low-energy hip fractures in middle-aged and elderly women. DESIGN: A register-based cohort study. SETTING: Finland. PARTICIPANTS: Women aged 45-75 years initiating statin the
Externí odkaz:
https://doaj.org/article/e18f8aaeea7c41ac8b56a45a11238cf1
Autor:
M. Finel, Aleksi Tornio, H. Kahma, Mikko T. Holmberg, Mikko Niemi, Mikko Neuvonen, Janne T. Backman, P. J. Neuvonen, E.K. Tarkiainen, Anne M. Filppula, Matti K. Itkonen
Publikováno v:
Clinical Therapeutics. 39:e70-e71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed4beeecc492bf1823950eca12e21e27
https://doi.org/10.1016/j.clinthera.2017.05.216
https://doi.org/10.1016/j.clinthera.2017.05.216
Publikováno v:
Acta Medica Scandinavica. 214:215-220
Three patients were treated after ingestion of an overdose of dapsone (1-10 g). A considerable acute cyanosis due to methaemoglobinaemia was followed by a late haemolysis within 1-2 weeks. Activated charcoal given orally in multiple doses (20 g X 4/d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d871a83cbf5b67b407229fcce7213675
https://doi.org/10.1111/j.0954-6820.1983.tb08597.x
https://doi.org/10.1111/j.0954-6820.1983.tb08597.x
Autor:
Ville Männistö, Mikko T. Holmberg, P. J. Neuvonen, Janne T. Backman, V. Kärjä, Mikko Niemi, Mikko Neuvonen, Maria Paile-Hyvärinen, Tuija Tapaninen, Matti K. Itkonen, J. Pihlajamäki, Aleksi Tornio, Päivi Hirvensalo, E.K. Tarkiainen
Publikováno v:
Clinical Therapeutics. 39:e12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473e680843982074c40b93b6cb05571d
https://doi.org/10.1016/j.clinthera.2017.05.038
https://doi.org/10.1016/j.clinthera.2017.05.038
Publikováno v:
European Journal of Clinical Pharmacology. 57:705-708
Objective: To study the effect of influenza vaccine on serum clozapine, N-desmethylclozapine and clozapine-N-oxide steady-state concentrations in patients with schizophrenia. Methods: This was an open-label study in 14 schizophrenic inpatients (with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a205335271bb8247eb911301b39c7f2a
https://doi.org/10.1007/s002280100375
https://doi.org/10.1007/s002280100375
Autor:
K. Raaska, P. J. Neuvonen
Publikováno v:
European Journal of Clinical Pharmacology. 56:585-589
Objective: A possible pharmacokinetic interaction between a CYP1A2 inhibitor, ciprofloxacin, and clozapine was studied in schizophrenia patients with stable clozapine treatment. Methods: A randomised double-blind cross-over study design with two phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d318517ffb13d16292180d5f110636
https://doi.org/10.1007/s002280000192
https://doi.org/10.1007/s002280000192
Publikováno v:
European Journal of Clinical Pharmacology. 56:285-288
Objective: To compare the efficacy of activated charcoal and gastric lavage in preventing the absorption of moclobemide, temazepam, and verapamil 30 min after drug ingestion. Methods: In this randomized cross-over study with three phases, nine health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8a0199a334cdffcd95ac7c2aee57be
https://doi.org/10.1007/s002280000139
https://doi.org/10.1007/s002280000139