Zobrazeno 1 - 10
of 14
pro vyhledávání: '"P J, Moos"'
Autor:
Philip J. Moos, Jenna R. Cheminant, Sophie Cowman, Jessica Noll, Qiuming Wang, Teresa Musci, Alessandro Venosa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGenetic mutations in critical nodes of pulmonary epithelial function are linked to the pathogenesis of pulmonary fibrosis (PF) and other interstitial lung diseases. The slow progression of these pathologies is often intermitted and accele
Externí odkaz:
https://doaj.org/article/81dbdcffe7f74feca597b0fad54c8e65
Autor:
Tosifa A. Memon, Lili Sun, Marysol Almestica-Roberts, Cassandra E. Deering-Rice, Philip J. Moos, Christopher A. Reilly
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 890 (2023)
This study tested whether a medicinal plant, Vasaka, typically consumed as a tea to treat respiratory malaise, could protect airway epithelial cells (AECs) from wood smoke particle-induced damage and prevent pathological mucus production. Wood/biomas
Externí odkaz:
https://doaj.org/article/25f254a5690442ce99c1e423d491d752
Autor:
Vince Kornél Grolmusz, Jinfeng Chen, Rena Emond, Patrick A. Cosgrove, Lance Pflieger, Aritro Nath, Philip J. Moos, Andrea H. Bild
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background CDK4/6 inhibitors such as ribociclib are becoming widely used targeted therapies in hormone-receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2−) breast cancer. However, cancers can advance due to dru
Externí odkaz:
https://doaj.org/article/e5a4169ce9df446384fbab9e6ed1de17
Autor:
Feng Chi, Jiayi Liu, Samuel W. Brady, Patrick A. Cosgrove, Aritro Nath, Jasmine A. McQuerry, Sumana Majumdar, Philip J. Moos, Jeffrey T. Chang, Michael Kahn, Andrea H. Bild
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100946- (2021)
Cancer cell phenotypes evolve during a tumor's treatment. In some cases, tumor cells acquire cancer stem cell-like (CSL) traits such as resistance to chemotherapy and diminished differentiation; therefore, targeting these cells may be therapeutically
Externí odkaz:
https://doaj.org/article/9abb045ac5a14f419c7e6853693a082c
Autor:
Samuel W. Brady, Jasmine A. McQuerry, Yi Qiao, Stephen R. Piccolo, Gajendra Shrestha, David F. Jenkins, Ryan M. Layer, Brent S. Pedersen, Ryan H. Miller, Amanda Esch, Sara R. Selitsky, Joel S. Parker, Layla A. Anderson, Brian K. Dalley, Rachel E. Factor, Chakravarthy B. Reddy, Jonathan P. Boltax, Dean Y. Li, Philip J. Moos, Joe W. Gray, Laura M. Heiser, Saundra S. Buys, Adam L. Cohen, W. Evan Johnson, Aaron R. Quinlan, Gabor Marth, Theresa L. Werner, Andrea H. Bild
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
In metastatic breast cancer, subclonal evolution can drive drug resistance. Here, the authors genetically and transcriptionally follow the evolution of four breast cancers over time and treatment, and suggest a phenotype-targeted treatment strategy t
Externí odkaz:
https://doaj.org/article/f22c7e1eec644bd49c349e24a268484e
Autor:
Stephen R Piccolo, Laura M Hoffman, Thomas Conner, Gajendra Shrestha, Adam L Cohen, Jeffrey R Marks, Leigh A Neumayer, Cori A Agarwal, Mary C Beckerle, Irene L Andrulis, Avrum E Spira, Philip J Moos, Saundra S Buys, William Evan Johnson, Andrea H Bild
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 3, Pp 1-16 (2016)
Abstract The signaling events that drive familial breast cancer (FBC) risk remain poorly understood. While the majority of genomic studies have focused on genetic risk variants, known risk variants account for at most 30% of FBC cases. Considering th
Externí odkaz:
https://doaj.org/article/ba0cc51becdf42c4b62521612685df32
Autor:
Nader N. El-Chaar, Thomas E. Smith, Gajendra Shrestha, Stephen R. Piccolo, Mary Kay Harper, Ryan M. Van Wagoner, Zhenyu Lu, Ashlee R. Venancio, Chris M. Ireland, Andrea H. Bild, Philip J. Moos
Publikováno v:
Marine Drugs, Vol 19, Iss 1, p 41 (2021)
Patients diagnosed with basal-like breast cancer suffer from poor prognosis and limited treatment options. There is an urgent need to identify new targets that can benefit patients with basal-like and claudin-low (BL-CL) breast cancers. We screened f
Externí odkaz:
https://doaj.org/article/2081d053526c453998348719d335d5c2
Autor:
Samuel W. Brady, Jasmine A. McQuerry, Yi Qiao, Stephen R. Piccolo, Gajendra Shrestha, David F. Jenkins, Ryan M. Layer, Brent S. Pedersen, Ryan H. Miller, Amanda Esch, Sara R. Selitsky, Joel S. Parker, Layla A. Anderson, Brian K. Dalley, Rachel E. Factor, Chakravarthy B. Reddy, Jonathan P. Boltax, Dean Y. Li, Philip J. Moos, Joe W. Gray, Laura M. Heiser, Saundra S. Buys, Adam L. Cohen, W. Evan Johnson, Aaron R. Quinlan, Gabor Marth, Theresa L. Werner, Andrea H. Bild
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this Article contained an error in Figure 4. In panel a, grey boxes surrounding the subclones associated with patients #2 and #4 obscured adjacent portions of the heatmap. This error has now been corrected in both
Externí odkaz:
https://doaj.org/article/ea7789e347e4466db080d56cf43f191a
Autor:
Jennifer J* Moos
Publikováno v:
Transposition, Vol 3 (2013)
This article explores the queer potentialities inherent in boy band culture. Boy band culture had its heyday during the mid- and late 1990s when innumerable boy bands were casted in order to successfully conquer the music market. The boy band phenome
Externí odkaz:
https://doaj.org/article/915946dd699e49aa999ff233322dbde7
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8786 (2010)
The selenoenzyme thioredoxin reductase 1 has a complex role relating to cell growth. It is induced as a component of the cellular response to potentially mutagenic oxidants, but also appears to provide growth advantages to transformed cells by inhibi
Externí odkaz:
https://doaj.org/article/dd72881f97934e94ad669347970a6755