Zobrazeno 1 - 10
of 40
pro vyhledávání: '"P J, Meffin"'
Publikováno v:
Biochemical pharmacology. 40(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61d9ea3ef53d2dffecd999b19ed270f
https://pubmed.ncbi.nlm.nih.gov/2403395
https://pubmed.ncbi.nlm.nih.gov/2403395
Publikováno v:
British Journal of Clinical Pharmacology. 4:519-522
1 We have measured the plasma concentration of acebutolol and a major metabolite in patients on chronic oral therapy with this drug, using a new assay, specific for each species. Our study suggests: 2 The acetyl metabolite was present in concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725a85e94864cd92c1adf04677648b0b
https://doi.org/10.1111/j.1365-2125.1977.tb00779.x
https://doi.org/10.1111/j.1365-2125.1977.tb00779.x
Autor:
A. H. Gradman, John W. Fitzgerald, Donald C. Harrison, Roger A. Winkle, J Stoner, P J Meffin, P. A. Bell
Publikováno v:
Circulation. 55:785-791
The antiarrhythmic action of the beta-blocking drug, acebutolol, was evaluated in patients with frequent premature ventricular contractions (PVCs). In the 12 hours following administration of a single 300 mg oral dose, 8 of 10 patients showed a great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3761d4aa4bc5a97eaa20cce17d541b
https://doi.org/10.1161/01.cir.55.5.785
https://doi.org/10.1161/01.cir.55.5.785
Publikováno v:
Australian and New Zealand Journal of Medicine. 13:583-586
Plasma concentrations of methylprednisolone following intra-articular injection were measured in rheumatoid arthritis and osteoarthritis patients. While substantial plasma concentrations were seen in both groups of patients there was no significant d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb6b490ff919cb9765ccf0017342e84
https://doi.org/10.1111/j.1445-5994.1983.tb02608.x
https://doi.org/10.1111/j.1445-5994.1983.tb02608.x
Publikováno v:
Biochemical Pharmacology. 37:3539-3542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cbfd6ee47eec779ef41b46ffd67a9b
https://doi.org/10.1016/0006-2952(88)90382-6
https://doi.org/10.1016/0006-2952(88)90382-6
Publikováno v:
Biochemical Pharmacology. 37:1919-1923
The formation of triacylglycerols containing fenoprofen was studied in rat isolated adipocytes and hepatocytes incubated with [3H]glycerol and R or S fenoprofen. In both hepatocytes and adipocytes there was a high-affinity enzymatic process for the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61340f8c6b8fb9339f9c89728ee26b4
https://doi.org/10.1016/0006-2952(88)90537-0
https://doi.org/10.1016/0006-2952(88)90537-0
Autor:
D.M. Zilm, P. J. Meffin
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 278:101-108
A high-performance liquid chromatographic method has been developed for the quantitation of [14C]clofibric acid glucuronide and [14C]clofibric acid using conventional scintillation counting. The assay has a linear relationship between the added and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4a81207838277171b9c0f8cf1cf6e2
https://doi.org/10.1016/s0378-4347(00)84760-x
https://doi.org/10.1016/s0378-4347(00)84760-x
Publikováno v:
Heart. 40:35-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6508ca5c2712231a77e5c646dd03b42
https://doi.org/10.1136/hrt.40.1.35
https://doi.org/10.1136/hrt.40.1.35
Publikováno v:
Clinical Pharmacology and Therapeutics. 29:351-358
Clofibric acid disposition was studied in four healthy men after 1 wk of clofibrate ingestion (500 mg orally every 12 hr) with and without probenecid (500 mg orally every 6 hr). Mean (±SD) free clofibric acid plasma concentration in the four subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa43d25f711e34e16289430fca6e576b
https://doi.org/10.1038/clpt.1981.48
https://doi.org/10.1038/clpt.1981.48
Autor:
Donald C. Harrison, Lisa E. Peters, Jeffrey L. Anderson, J W Mason, Roger A. Winkle, P J Meffin, R E Fowles
Publikováno v:
Circulation. 57:685-691
The electrophysiologic properties of tocainide were evaluated by electrophysiologic studies in 11 patients before, during and after a constant intravenous infusion of the drug for 15 minutes. Peak plasma tocainide concentrations averaged 11.0 +/- 1.7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b219e9e979fa8ef8a543a8ed1016f8e
https://doi.org/10.1161/01.cir.57.4.685
https://doi.org/10.1161/01.cir.57.4.685