Zobrazeno 1 - 8
of 8
pro vyhledávání: '"P J, McFie"'
The monoacylglycerol acyltransferase pathway contributes to triacylglycerol synthesis in HepG2 cells
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The monoacylglycerol acyltransferase (MGAT) pathway has a well-established role in the small intestine where it facilitates the absorption of dietary fat. In enterocytes, MGAT participates in the resynthesis of triacylglycerol using substrat
Externí odkaz:
https://doaj.org/article/87fe8281c5de4bb18df92615d1f0d8bc
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210396 (2019)
Triacylglycerol synthesis is catalyzed by acyl CoA:diacylglycerol acyltransferase-2 (DGAT2). DGAT2 is an integral membrane protein that is localized to the endoplasmic reticulum and interacts with lipid droplets. Using BioId, a method to detect proxi
Externí odkaz:
https://doaj.org/article/b2acf3ebbbb84957951342e75ee9586c
Autor:
Christopher J. Hlynialuk, Binbing Ling, Zakery N. Baker, Paul A. Cobine, Lisa D. Yu, Aren Boulet, Timothy Wai, Amzad Hossain, Amr M. El Zawily, Pamela J. McFie, Scot J. Stone, Francisca Diaz, Carlos T. Moraes, Deepa Viswanathan, Michael J. Petris, Scot C. Leary
Publikováno v:
Cell Reports, Vol 10, Iss 6, Pp 933-943 (2015)
Human SCO1 fulfills essential roles in cytochrome c oxidase (COX) assembly and the regulation of copper (Cu) homeostasis, yet it remains unclear why pathogenic mutations in this gene cause such clinically heterogeneous forms of disease. Here, we esta
Externí odkaz:
https://doaj.org/article/0340b7e99d004b629b58872104cbc6a2
Autor:
Pamela J. McFie, Scot J. Stone
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 9, Pp 1760-1764 (2011)
Triacylglycerols (TG) are the major storage form of energy in eukaryotic organisms and are synthesized primarily by acyl CoA:1,2-diacylglycerol acyltransferase (DGAT) enzymes. In vitro DGAT activity has previously been quantified by measuring the inc
Externí odkaz:
https://doaj.org/article/368b7becdd8545f3b42d0987d06500c5
Publikováno v:
The Journal of biological chemistry. 269(19)
The cAMP response unit of the phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) gene promoter consists of two independently weak components; the typical cAMP response element and a region of the promoter that contains three binding sites for CCAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32880abe6d15336d9d86d4b5a21a7b98
https://pubmed.ncbi.nlm.nih.gov/8188712
https://pubmed.ncbi.nlm.nih.gov/8188712
Publikováno v:
The Journal of biological chemistry. 268(5)
A detailed analysis of the promoter sequence requirements for the cAMP induction of transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) was undertaken. It was determined that the cAMP-responsive unit of this promoter c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5d3a39bc4e50bf576ef91dd41b12d2e
https://pubmed.ncbi.nlm.nih.gov/8381439
https://pubmed.ncbi.nlm.nih.gov/8381439
Publikováno v:
The Journal of biological chemistry. 267(29)
It has been previously demonstrated that the CCAAT/enhancer-binding protein (C/EBP) trans-activates the gene coding for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) and binds to several sites along the promoter.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52e0e32647af686934ca4d4c52e46002
https://pubmed.ncbi.nlm.nih.gov/1328227
https://pubmed.ncbi.nlm.nih.gov/1328227
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; January 2002, Vol. 300 Issue: 1 p72-7, 6p