Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P J, Leibowitz"'
Autor:
Bogdan Kochetov, Phoenix D. Bell, Paulo S. Garcia, Akram S. Shalaby, Rebecca Raphael, Benjamin Raymond, Brian J. Leibowitz, Karen Schoedel, Rhonda M. Brand, Randall E. Brand, Jian Yu, Lin Zhang, Brenda Diergaarde, Robert E. Schoen, Aatur Singhi, Shikhar Uttam
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Multiplexed imaging technologies have made it possible to interrogate complex tissue microenvironments at sub-cellular resolution within their native spatial context. However, proper quantification of this complexity requires the ability to
Externí odkaz:
https://doaj.org/article/874dc85ae11740acb138f7e5d23648d4
Autor:
Hang Ruan, Brian J. Leibowitz, Yingpeng Peng, Lin Shen, Lujia Chen, Charlie Kuang, Robert E. Schoen, Xinghua Lu, Lin Zhang, Jian Yu
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-16 (2022)
Abstract Mutant KRAS is a key driver in colorectal cancer (CRC) and promotes Myc translation and Myc-dependent stress adaptation and proliferation. Here, we report that the combination of two FDA-approved drugs Bortezomib and Everolimus (RAD001) (BR)
Externí odkaz:
https://doaj.org/article/897eff7e4d3547fe9e1e5347bbb62633
Autor:
Jim O. Vigoreaux, Michael J. Leibowitz
Publikováno v:
BMC Proceedings, Vol 15, Iss S2, Pp 1-11 (2021)
Abstract Progressing from postdoctoral training to a STEM faculty appointment at a Research Intensive Institution (RII) is a daunting transition, and may be especially challenging to those who have followed a less-than-conventional path or whose peer
Externí odkaz:
https://doaj.org/article/4e291f4dabef4cf8b290dc0c7a5be39d
Autor:
Hang Ruan, Xiangyun Li, Xiang Xu, Brian J Leibowitz, Jingshan Tong, Lujia Chen, Luoquan Ao, Wei Xing, Jianhua Luo, Yanping Yu, Robert E Schoen, Nahum Sonenberg, Xinghua Lu, Lin Zhang, Jian Yu
Publikováno v:
eLife, Vol 9 (2020)
To better understand a role of eIF4E S209 in oncogenic translation, we generated EIF4ES209A/+ heterozygous knockin (4EKI) HCT 116 human colorectal cancer (CRC) cells. 4EKI had little impact on total eIF4E levels, cap binding or global translation, bu
Externí odkaz:
https://doaj.org/article/8097d9190a1f4efdac858b6f81908cd6
Autor:
Verónica A. Segarra, Sydella Blatch, Michael Boyce, Franklin Carrero-Martinez, Renato J. Aguilera, Michael J. Leibowitz, MariaElena Zavala, Latanya Hammonds-Odie, Ashanti Edwards
Publikováno v:
Journal of Microbiology & Biology Education, Vol 21, Iss 1 (2020)
Promoting diversity and inclusiveness in the STEM academic workforce remains a key challenge and national priority. Scientific societies can play a significant role in this process through the creation and implementation of programs to foster STEM ac
Externí odkaz:
https://doaj.org/article/2973f874a7fc45cc92425afdb7658906
Autor:
Alexander Orenstein, April S. Berlyoung, Elizabeth E. Rastede, Ha H. Pham, Elise Fouquerel, Connor T. Murphy, Brian J. Leibowitz, Jian Yu, Tumul Srivastava, Bruce A. Armitage, Patricia L. Opresko
Publikováno v:
Molecules, Vol 22, Iss 12, p 2117 (2017)
Measurement of telomere length by fluorescent in situ hybridization is widely used for biomedical and epidemiological research, but there has been relatively little development of the technology in the 20 years since it was first reported. This repor
Externí odkaz:
https://doaj.org/article/44f26b3164ba46ea970cd1183b6c4959
Publikováno v:
Journal of biological response modifiers. 6(2)
Two human tumor cell lines were studied for their response to the antiproliferative effect of recombinant human interferons (IFNs) alpha 2, alpha 4, a hybrid alpha (delta 4 alpha 2 Bgl II alpha 1), and gamma, individually and in combination. Natural
Autor:
P J, Leibowitz, M, Schaechter
Publikováno v:
International review of cytology. 41
Autor:
S J, Jacobs, L M, Sullivan, M, Salfi, H, Grossberg, R J, Spiegel, P J, Leibowitz, E M, Oden, D K, Kelsey, M W, Treuhaft
Publikováno v:
Journal of biological response modifiers. 7(5)
Antibodies to recombinant human interferon alpha 2b (Intron A) were detected in only a small number of 101 Intron A recipients. This group of cancer patients received Intron A for a mean treatment time of 4.3 months and were selected from disease cat
Autor:
T. L. Nagabhushan, P. J. Leibowitz
Publikováno v:
Interferon Alpha-2: Pre-Clinical and Clinical Evaluation ISBN: 9781461296188
The strain of E. coli, KMAC-43, used for the large-scale production of alpha-2 interferon was engineered at Schering by Leibowitz and his co-workers. The alpha-2 interferon gene used in this construction was obtained from a cDNA clone, Hif-SN206, dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::290f9b961d2875c7f2b672f6d21fffa2
https://doi.org/10.1007/978-1-4613-2579-6_1
https://doi.org/10.1007/978-1-4613-2579-6_1