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Akademický článek

A multiplexed barcode approach to simultaneously evaluate gene delivery by adeno-associated virus capsid variants in nonhuman primates

Publikováno v: Hepatology Communications, Vol 7, Iss 2, Pp e0009-e0009 (2023)

Background and Aims:. Adeno-associated virus (AAV) vectors are widely used to deliver therapeutic transgenes to distinct tissues, including the liver. Vectors based on naturally occurring AAV serotypes as well as vectors using engineered capsids have

Externí odkaz: https://doaj.org/article/1d40d622a45b4cc6aa011947303c4dea

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Akademický článek

Bone Marrow Aplasia after CAR-T-Cell Therapy for Relapsed/Refractory Burkitt’s Lymphoma

Autor: Troy J. Kenkel, Nithya Sridhar, Lindsay R. Hammons, Maria Hintzke, Nirav N. Shah

Publikováno v: Medical Sciences, Vol 11, Iss 4, p 67 (2023)

Chimeric antigen receptor T-cells (CAR-T) are now a standard approach for treating relapsed/refractory B-cell lymphomas. Immune effector cell-associated hemophagocytic lymphohistiocytosis-like syndrome (IEC-HS) is a newly described entity that can ma

Externí odkaz: https://doaj.org/article/69cfcb1c11764a18bc894a17dc38cda9

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Akademický článek

CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 258-275 (2021)

Chronic hepatitis B virus (HBV) infection is a major public health problem. New treatment approaches are needed because current treatments do not target covalently closed circular DNA (cccDNA), the template for HBV replication, and rarely clear the v

Externí odkaz: https://doaj.org/article/50136f1751074d8594ac5811c80e88ea

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Alliances for HMO growth

Autor: P J, Kenkel

Publikováno v: Modern healthcare. 24(18)

With the accelerating trend toward managed care, health providers and insurers are scrambling to form exclusive arrangements that will allow them to capture a larger slice of the managed-care market. A Modern Healthcare survey confirms growth in HMO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c87400c1a428e1d100c7db2ceeb5adc3
https://pubmed.ncbi.nlm.nih.gov/10133234

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