Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P J, Kannankeril"'
Autor:
Allison J. Weatherly, MD, Cassandra A. Johnson, MS, Dandan Liu, PhD, Prince J. Kannankeril, MD, MSCI, Heidi A.B. Smith, MD, MSCI, FAAP, Kristina A. Betters, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1119 (2024)
OBJECTIVE:. ICU delirium commonly complicates critical illness associated with factors such as cardiopulmonary bypass (CPB) time and the requirement of mechanical ventilation (MV). Recent reports associate hyperoxia with poorer outcomes in critically
Externí odkaz:
https://doaj.org/article/a3e492835f584a11830f0227d8cc3d18
Autor:
Megan J. Puckelwartz, Lorenzo L. Pesce, Edgar J. Hernandez, Gregory Webster, Lisa M. Dellefave-Castillo, Mark W. Russell, Sarah S. Geisler, Samuel D. Kearns, Felix Karthik, Susan P. Etheridge, Tanner O. Monroe, Tess D. Pottinger, Prince J. Kannankeril, M. Benjamin Shoemaker, Darlene Fountain, Dan M. Roden, Meghan Faulkner, Heather M. MacLeod, Kristin M. Burns, Mark Yandell, Martin Tristani-Firouzi, Alfred L. George, Elizabeth M. McNally
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Sudden unexpected death in children is a tragic event. Understanding the genetics of sudden death in the young (SDY) enables family counseling and cascade screening. The objective of this study was to characterize genetic variatio
Externí odkaz:
https://doaj.org/article/754c31b062b14f8fb5738e1f18f62142
Autor:
Eric L. Eisenstein, Kevin D. Hill, Nancy Wood, Jerry L. Kirchner, Kevin J. Anstrom, Christopher B. Granger, Sunil V. Rao, H. Scott Baldwin, Jeffrey P. Jacobs, Marshall L. Jacobs, Prince J. Kannankeril, Eric M. Graham, Sean M. O'Brien, Jennifer S. Li
Publikováno v:
Contemporary Clinical Trials Communications, Vol 38, Iss , Pp 101257- (2024)
Background: Registry-based trials have the potential to reduce randomized clinical trial (RCT) costs. However, observed cost differences also may be achieved through pragmatic trial designs. A systematic comparison of trial costs across different des
Externí odkaz:
https://doaj.org/article/7912ef2ef50e4a909f9255670edbac5b
Autor:
Aleksandra Polic, MD, Stacy A.S. Killen, MD, MSCI, Janette F. Strasburger, MD, Prince J. Kannankeril, MD, MSCI, Ronald T. Wakai, PhD, Soha S. Patel, MD, MSPH
Publikováno v:
JACC: Case Reports, Vol 29, Iss 3, Pp 102183- (2024)
A low baseline fetal heart rate at 20 weeks’ gestation was detected in a fetus without cardiac structural anomalies. Fetal echocardiography and magnetocardiography were used to diagnose congenital long QT syndrome. It was confirmed in the neonate,
Externí odkaz:
https://doaj.org/article/354f972781f04be78996603f2c6f53b7
Autor:
Sudeep D. Sunthankar, Prince J. Kannankeril, Andrea Gaedigk, Andrew E. Radbill, Frank A. Fish, Sara L. Van Driest
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 7, Pp 1787-1795 (2022)
Abstract Propafenone is an antiarrhythmic drug metabolized primarily by cytochrome P450 2D6 (CYP2D6). In adults, propafenone adverse events (AEs) are associated with CYP2D6 poor metabolizer status; however, pediatric data are lacking. Subjects were t
Externí odkaz:
https://doaj.org/article/6026c7e303044f3babf4a37c9394b561
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Atrial fibrillation (AF) is the most common human arrhythmia and is associated with increased risk of stroke, dementia, heart failure, and death. Among several animal models that have been used to investigate the molecular determinants of AF, mouse m
Externí odkaz:
https://doaj.org/article/ef7c31c6489b4e488f970b79020cb8d4
Autor:
A T Bergeman, M W Tanck, D Kallas, S Sanatani, A Leenhardt, M J Ackerman, J Till, E Zorio, P J Kannankeril, J A E Kammeraad, T Aiba, C Semsarian, T Robyns, A A M Wilde, C Van Der Werf
Publikováno v:
Europace. 25
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): This work was supported by the ZonMW Priority Medicines for Rare Diseases and Orphan Drugs (grant 113304045 to Dr Van der Werf) and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a2fdd81960d2956a002e53c2553a535
https://doi.org/10.1093/europace/euad122.301
https://doi.org/10.1093/europace/euad122.301
Autor:
Rachel D. Torok, Jennifer S. Li, Prince J. Kannankeril, Andrew M. Atz, Raafat Bishai, Ellen Bolotin, Stefanie Breitenstein, Cathy Chen, Thomas Diacovo, Timothy Feltes, Patricia Furlong, Michael Hanna, Eric M. Graham, Daphne Hsu, D. Dunbar Ivy, Dianne Murphy, Lisa A. Kammerman, Gregory Kearns, John Lawrence, Brigitte Lebeaut, Danshi Li, Christoph Male, Brian McCrindle, Pierre Mugnier, Jane W. Newburger, Gail D. Pearson, Vasum Peiris, Lisa Percival, Miriam Pina, Ronald Portman, Robert Shaddy, Norman L. Stockbridge, Robert Temple, Kevin D. Hill
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 4 (2018)
Externí odkaz:
https://doaj.org/article/358997288c0745aea8f714749db9b506
Autor:
Sara L Van Driest, Tracy L McGregor, Digna R Velez Edwards, Ben R Saville, Terrie E Kitchner, Scott J Hebbring, Murray Brilliant, Hayan Jouni, Iftikhar J Kullo, C Buddy Creech, Prince J Kannankeril, Susan I Vear, Kyle B Brothers, Erica A Bowton, Christian M Shaffer, Neelam Patel, Jessica T Delaney, Yuki Bradford, Sarah Wilson, Lana M Olson, Dana C Crawford, Amy L Potts, Richard H Ho, Dan M Roden, Josh C Denny
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127791 (2015)
Vancomycin, a commonly used antibiotic, can be nephrotoxic. Known risk factors such as age, creatinine clearance, vancomycin dose / dosing interval, and concurrent nephrotoxic medications fail to accurately predict nephrotoxicity. To identify potenti
Externí odkaz:
https://doaj.org/article/d1b2a61fcf654975a0b71ba96a9457bc
Publikováno v:
Indian Pacing and Electrophysiology Journal, Vol 6, Iss 1, Pp 32-43 (2006)
Andersen-Tawil syndrome (ATS) is a rare condition consisting of ventricular arrhythmias, periodic paralysis, and dysmorphic features. In 2001, mutations in KCNJ2, which encodes the α subunit of the potassium channel Kir2.1, were identified in patien
Externí odkaz:
https://doaj.org/article/f8d66bf4a00d4aa9b981473f7399c7d0