Zobrazeno 1 - 10
of 352
pro vyhledávání: '"P J, Hughes"'
Autor:
Neil Daniel, Riccardo Farinella, Anastasia Chrysovalantou Chatziioannou, Mazda Jenab, Ana-Lucia Mayén, Cosmeri Rizzato, Flavia Belluomini, Federico Canzian, Arianna Tavanti, Pekka Keski-Rahkonen, David J. Hughes, Daniele Campa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) has high mortality and rising incidence rates. Recent data indicate that the gut microbiome and associated metabolites may play a role in the development of PDAC. To complement and inform observational
Externí odkaz:
https://doaj.org/article/da2d98f474ff4bada2734a28ec4ef6e1
Publikováno v:
Animal Microbiome, Vol 6, Iss 1, Pp 1-18 (2024)
Abstract Animal guts contain numerous microbes, which are critical for nutrient assimilation and pathogen defence. While corals and other Cnidaria lack a true differentiated gut, they possess semi-enclosed gastrovascular cavities (GVCs), where vital
Externí odkaz:
https://doaj.org/article/882befa2891e4f1885a895768785a772
Autor:
Hadley England, Andrei Herdean, Jennifer Matthews, David J. Hughes, Christine D. Roper, David J. Suggett, Christian R. Voolstra, Emma F. Camp
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Organismal phenotyping to identify fitness traits is transforming our understanding of adaptive responses and ecological interactions of species within changing environments. Here we present a portable Multi-Taxa Phenotyping (MTP) system tha
Externí odkaz:
https://doaj.org/article/15dccc1ad4714687b6dae56eaef6ec51
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 5, Pp 2718-2728 (2024)
Abstract Background Diarrhea in foals can be associated with disruption of the intestinal microbiota (dysbiosis). Effective management of intestinal dysbiosis in foals has not been demonstrated. Hypothesis/Objectives Fecal microbiota transplantation
Externí odkaz:
https://doaj.org/article/e564065a85fd4c648a65f3ba1ee48b1c
Autor:
Song Han, Steven J Hughes, Gerik W Tushoski-Alemán, Alexandra J Crespin, Chibeze J Oguejiofor, Dominique D Szymkiewicz, Kelly M Herremans
Publikováno v:
BMJ Open, Vol 14, Iss 11 (2024)
Objectives This systematic review aims to evaluate the methodology used in pancreatic cancer (PC) randomised controlled trials (RCTs) measuring quality of life (QOL) and focuses on the type, frequency, survey compliance and duration of these assessme
Externí odkaz:
https://doaj.org/article/b1a25df2c502421cb9113e809c1253c1
Autor:
Isabel P. Prado, Eoghan T. Hurley, Richard M. Danilkowicz, Asheesh Bedi, Alexander Golant, John A. Grant, Andrew J. Hughes, Mike McNicholas, Matthew Salzler, Ian Savage-Elliott, Aaron J. Krych
Publikováno v:
Journal of Cartilage & Joint Preservation, Vol 4, Iss 3, Pp 100192- (2024)
Introduction: Articular cartilage injuries of the knee are a complex and challenging clinical pathology. Objectives: The purpose of this study was to establish consensus statements via a Delphi process on clinical and research follow-up for knee cart
Externí odkaz:
https://doaj.org/article/b7ca504306f74a6eb7b511c85cba24b6
Autor:
Dhruv S. Shankar, Zachary I. Li, Jairo Triana, Jordan A. Eskenazi, Rae Lan, Andrew J. Hughes, Thomas Youm
Publikováno v:
Surgeries, Vol 5, Iss 2, Pp 194-205 (2024)
Females of reproductive age constitute one of the largest demographics of the hip arthroscopy population, but it is unclear as to how pregnancy planning affects decision-making regarding surgery or vice versa. The purpose of this study was to assess
Externí odkaz:
https://doaj.org/article/b4cf98ae30674606ad7b9d4487a29d3a
Autor:
FC Sampson, J Hughes, J Long, P Buykx, SW Goodacre, H Snooks, A Edwards, Bridie Evans, Jenna Jones, Chris Moore, Sasha Johnston
Publikováno v:
BMC Emergency Medicine, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Objective Distribution of take-home naloxone (THN) by emergency services may increase access to THN and reduce deaths and morbidity from opioid overdose. As part of a feasibility study for a randomised controlled trial (RCT) of distribution
Externí odkaz:
https://doaj.org/article/67b3bf6908db47639f9dea556c78c978
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background There are currently no data on the relationship between frailty and mortality in pleural disease. Understanding the relationship between frailty and outcomes is increasingly important for clinicians to guide decisions regarding in
Externí odkaz:
https://doaj.org/article/f4cd3d25389642ef882c9f8ce604cdaf
Autor:
Song Han, Gerik W. Tushoski-Alemán, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Zhiguang Huo, Jonathan Licht, Thomas J. George, Carmen Allegra, Jose G. Trevino, Steven J. Hughes
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101070- (2025)
Oncogenic KRAS signaling plays a critical role in pancreatic ductal adenocarcinoma (PDAC) biology. Recent studies indicate that the combination of MEK and BCL-xL inhibition is synthetically lethal and holds promise for some types of solid cancers, ho
Externí odkaz:
https://doaj.org/article/191df517e9ab4a0b927c1c49c80b247d