Zobrazeno 1 - 10
of 137
pro vyhledávání: '"P J, Hammond"'
Autor:
Santiago Diaz-Torres, Weixiong He, Regina Yu, IGGC International Glaucoma Genetics Consortium, Anthony P. Khawaja, Christopher J. Hammond, Pirro G. Hysi, Louis R. Pasquale, Yeda Wu, Michiaki Kubo, Masato Akiyama, Tin Aung, Ching-Yu Cheng, Chiea Chuen Khor, Peter Kraft, Jae H. Kang, Alex W. Hewitt, David A. Mackey, Jamie E. Craig, Janey L. Wiggs, Jue-Sheng Ong, Stuart MacGregor, Puya Gharahkhani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Primary open-angle glaucoma typically presents as two subtypes. This study aimed to elucidate the shared and distinct genetic architectures of normal-tension (NTG) and high-tension glaucoma (HTG), motivated by the need to develop intraocular
Externí odkaz:
https://doaj.org/article/922ae413070b45558acecb577bd65aed
Autor:
Joshua L. Robinson, Andrea J. Roff, Sarah J. Hammond, Jack R. T. Darby, Ashley S. Meakin, Stacey L. Holman, Andrew Tai, Tim J. M. Moss, Catherine G. Dimasi, Sarah M. Jesse, Michael D. Wiese, Andrew N. Davies, Beverly S. Muhlhausler, Robert J. Bischof, Megan J. Wallace, Vicki L. Clifton, Janna L. Morrison, Michael J. Stark, Kathryn L. Gatford
Publikováno v:
Experimental Physiology, Vol 109, Iss 11, Pp 1967-1979 (2024)
Abstract Maternal asthma is associated with increased rates of neonatal lung disease, and fetuses from asthmatic ewes have fewer surfactant‐producing cells and lower surfactant‐protein B gene (SFTPB) expression than controls. Antenatal betamethas
Externí odkaz:
https://doaj.org/article/9638ec5be75e4576afa102657005a265
Publikováno v:
Health Psychology and Behavioral Medicine, Vol 12, Iss 1 (2024)
Multiple weight loss attempts, and weight regain are common. Various lifestyle changes are often required for success, but just diet and exercise are often promoted. The amount of lifestyle changes needed for successful weight management is still unc
Externí odkaz:
https://doaj.org/article/996892373cc8403ea75a9409271299a2
Autor:
Jack R. T. Darby, Brahmdeep S. Saini, Stacey L. Holman, Sarah J. Hammond, Sunthara Rajan Perumal, Christopher K. Macgowan, Mike Seed, Janna L. Morrison
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionThe fetal haemodynamic response to acute episodes of hypoxaemia are well characterised. However, how these responses change when the hypoxaemia becomes more chronic in nature such as that associated with fetal growth restriction (FGR), is
Externí odkaz:
https://doaj.org/article/3e5e45377bfd4531afb0d08f7547afd1
Autor:
Anthony M. Musolf, Annechien E. G. Haarman, Robert N. Luben, Jue-Sheng Ong, Karina Patasova, Rolando Hernandez Trapero, Joseph Marsh, Ishika Jain, Riya Jain, Paul Zhiping Wang, Deyana D. Lewis, Milly S. Tedja, Adriana I. Iglesias, Hengtong Li, Cameron S. Cowan, Consortium for Refractive Error and Myopia (CREAM), Ginevra Biino, Alison P. Klein, Priya Duggal, David A. Mackey, Caroline Hayward, Toomas Haller, Andres Metspalu, Juho Wedenoja, Olavi Pärssinen, Ching-Yu Cheng, Seang-Mei Saw, Dwight Stambolian, Pirro G. Hysi, Anthony P. Khawaja, Veronique Vitart, Christopher J. Hammond, Cornelia M. van Duijn, Virginie J. M. Verhoeven, Caroline C. W. Klaver, Joan E. Bailey-Wilson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
A multi-ethnic meta-analysis of exome array data from over 27,000 participants identifies several rare variants that could contribute to risk of ocular refractive error.
Externí odkaz:
https://doaj.org/article/bd8c4caa72a641eab1075fd26afb62da
Autor:
Santiago Diaz-Torres, Weixiong He, Jackson Thorp, Sahba Seddighi, Sean Mullany, Christopher J. Hammond, Pirro G. Hysi, Louis R. Pasquale, Anthony P. Khawaja, Alex W. Hewitt, Jamie E. Craig, David A. Mackey, Janey L. Wiggs, Cornelia van Duijn, Michelle K. Lupton, Jue-Sheng Ong, Stuart MacGregor, Puya Gharahkhani
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104615- (2023)
Summary: Background: Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by progressive degeneration of the optic nerve that leads to irreversible visual impairment. Multiple epidemiological studies suggest an association between
Externí odkaz:
https://doaj.org/article/998bca0455cc4d5c8fd546e1ecf16ea5
Autor:
Xiaofan Jiang, Pirro G Hysi, Anthony P Khawaja, Omar A Mahroo, Zihe Xu, Christopher J Hammond, Paul J Foster, Roshan A Welikala, Sarah A Barman, Peter H Whincup, Alicja R Rudnicka, Christopher G Owen, David P Strachan, UK Biobank Eye and Vision Consortium
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010583 (2023)
The eye is the window through which light is transmitted and visual sensory signalling originates. It is also a window through which elements of the cardiovascular and nervous systems can be directly inspected, using ophthalmoscopy or retinal imaging
Externí odkaz:
https://doaj.org/article/150ba4a65ad84908a2b6b5575876bebf
Autor:
Pravesh Sharma, Ashley Holland, Taharat Sheikh, Blake Novy, Tyler Oesterle, Rheanna Platt, Christopher J. Hammond
Publikováno v:
PEC Innovation, Vol 1, Iss , Pp 100044- (2022)
Objectives: Federal hemp legalization and ongoing shifts in US marijuana laws have led to increased population-wide use of cannabidiol (CBD) supplements, often without the knowledge of primary healthcare providers (PCPs). Given the potential risks re
Externí odkaz:
https://doaj.org/article/2aad0f6ff8104a2f80e4a8f4bb41f78b
Autor:
Vincent Bombail, Alistair B. Lawrence, Ignacio Vinuela-Fernandez, Emma K.L. Tivey, Birte L. Nielsen, Megan R. LaFollette, Emma S.J. Robinson, Tayla J. Hammond, Simone L. Meddle, Michael Mendl, Sarah M. Brown, Jessica E. Martin
Publikováno v:
F1000Research, Vol 11 (2022)
Rat tickling is a heterospecific interaction for experimenters to mimic the interactions of rat play, where they produce 50 kHz ultrasonic vocalisations (USV), symptoms of positive affect; tickling can improve laboratory rat welfare. The standard rat
Externí odkaz:
https://doaj.org/article/a42e69c846804bcd908b508f5fe18b7e
Autor:
Dimitrios Stavropoulos, Manjot K. Grewal, Bledi Petriti, Kai-Yin Chau, Christopher J. Hammond, David F. Garway-Heath, Gerassimos Lascaratos
Publikováno v:
Cells, Vol 12, Iss 15, p 1969 (2023)
This review aims to provide a better understanding of the emerging role of mitophagy in glaucomatous neurodegeneration, which is the primary cause of irreversible blindness worldwide. Increasing evidence from genetic and other experimental studies su
Externí odkaz:
https://doaj.org/article/8bc23e92ecfd497988c6ec2e38382006