Zobrazeno 1 - 10
of 12
pro vyhledávání: '"P J, Grisdale"'
Autor:
Caralyn Reisle, Laura M. Williamson, Erin Pleasance, Anna Davies, Brayden Pellegrini, Dustin W. Bleile, Karen L. Mungall, Eric Chuah, Martin R. Jones, Yussanne Ma, Eleanor Lewis, Isaac Beckie, David Pham, Raphael Matiello Pletz, Amir Muhammadzadeh, Brandon M. Pierce, Jacky Li, Ross Stevenson, Hansen Wong, Lance Bailey, Abbey Reisle, Matthew Douglas, Melika Bonakdar, Jessica M. T. Nelson, Cameron J. Grisdale, Martin Krzywinski, Ana Fisic, Teresa Mitchell, Daniel J. Renouf, Stephen Yip, Janessa Laskin, Marco A. Marra, Steven J. M. Jones
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The interpretation of somatic variants in cancer is challenging due to the scale and complexity of sequencing data. Here, the authors present PORI, an open-source framework for interpreting somatic variants in cancer using graph knowledge base tools,
Externí odkaz:
https://doaj.org/article/5c7ff25c4b804a56a09afa4f5a34016d
Autor:
Astrid De Boeck, Bo Young Ahn, Charlotte D’Mello, Xueqing Lun, Shyam V. Menon, Mana M. Alshehri, Frank Szulzewsky, Yaoqing Shen, Lubaba Khan, Ngoc Ha Dang, Elliott Reichardt, Kimberly-Ann Goring, Jennifer King, Cameron J. Grisdale, Natalie Grinshtein, Dolores Hambardzumyan, Karlyne M. Reilly, Michael D. Blough, J. Gregory Cairncross, V. Wee Yong, Marco A. Marra, Steven J. M. Jones, David R. Kaplan, Kathy D. McCoy, Eric C. Holland, Pinaki Bose, Jennifer A. Chan, Stephen M. Robbins, Donna L. Senger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-24 (2020)
Elevated levels of interleukin-33 have been associated with poor prognosis in patients with glioma. Here the authors show that glioma-derived IL-33 modulates a pro-tumorigenic immune microenvironment by activating resident and recruiting peripheral i
Externí odkaz:
https://doaj.org/article/1b3e75d138fe4626bae55cdc8321e3d1
Autor:
Yiqun Zhang, Fengju Chen, Erin Pleasance, Laura Williamson, Cameron J. Grisdale, Emma Titmuss, Janessa Laskin, Steven J.M. Jones, Isidro Cortes-Ciriano, Marco A. Marra, Chad J. Creighton
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 110023- (2021)
Summary: The global impact of somatic structural variants (SVs) on gene regulation in advanced tumors with complex treatment histories has been mostly uncharacterized. Here, using whole-genome and RNA sequencing from 570 recurrent or metastatic tumor
Externí odkaz:
https://doaj.org/article/edab694d74344c2b892a199e86fb5c24
Autor:
Arpad M. Danos, Kilannin Krysiak, Erica K. Barnell, Adam C. Coffman, Joshua F. McMichael, Susanna Kiwala, Nicholas C. Spies, Lana M. Sheta, Shahil P. Pema, Lynzey Kujan, Kaitlin A. Clark, Amber Z. Wollam, Shruti Rao, Deborah I. Ritter, Dmitriy Sonkin, Gordana Raca, Wan-Hsin Lin, Cameron J. Grisdale, Raymond H. Kim, Alex H. Wagner, Subha Madhavan, Malachi Griffith, Obi L. Griffith
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-12 (2019)
Abstract Manually curated variant knowledgebases and their associated knowledge models are serving an increasingly important role in distributing and interpreting variants in cancer. These knowledgebases vary in their level of public accessibility, a
Externí odkaz:
https://doaj.org/article/39ec4aa7be3443f3b794858501c8d184
Publikováno v:
Journal of Preventive Medicine and Hygiene
This study, part of the health promotion program of a high school in Milan (Italy), was aimed at evaluating the impact of training conferences on the awareness of STIs among adolescents aged 16-17. Students attending the 3rd class of a Scientific and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c779a0b0e0a58cfcf7c574d86a70a195
Publikováno v:
Canadian Journal of Chemistry. 47:2355-2359
The base strengths of various 2- and 4-styrylpyridines in the ground state and first-excited-singlet state have been determined. The base strengths are found to conform to the Hammett equation if the proper σ values are chosen.
Publikováno v:
Chemischer Informationsdienst. 5
Autor:
A. Okany, P. J. Grisdale
Publikováno v:
Canadian journal of biochemistry. 43(6)
Preparative thin-layer chromatography, combined with published procedures, has facilitated the isolation of chromatographically homogeneous phosphatidylserine, phosphatidylethanolamine, and lysophosphatidylethanolamine. The effect of these compounds
Autor:
A. Okany, P. J. Grisdale
Publikováno v:
Canadian journal of biochemistry. 43(9)
A series of synthetic phosphatidylserines containing saturated fatty ester residues (C6 to C18) has been synthesized. These compounds have been studied in combination with natural phosphatidylethanolamine in the two-stage thromboplastin-generation te
Autor:
P. J. Grisdale, J. L. R. Williams
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 1