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Akademický článek

Management of calves in commercial dairy farms in Mecklenburg-Western Pomerania, Germany and its impact on calf mortality and prevalence of rotavirus and Cryptosporidium parvum infections in pre-weaned calves

Autor: U. Falkenberg, V. Krömker, M. Konow, J. Flor, P. Sanftleben, B. Losand

Publikováno v: Veterinary and Animal Science, Vol 16, Iss , Pp 100243- (2022)

In a cross-sectional study, impact of management in dairy farms on calf mortality rates and prevalence of rotavirus and Cryptosporidium parvum in feces of calves was investigated. Sixty-two commercial dairy herds in Mecklenburg-Western Pomerania, Ger

Externí odkaz: https://doaj.org/article/e6259e26785b4fb8bbf8096ffecb2c63

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Akademický článek

Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice

Autor: Karolyne A. R. Estrela, Lisa Senninger, Josephine Arndt, Melanie Kabas, Ferdinand Schmid, Larissa Dillmann, Sophia Auer, Thomas Stepfer, Peter J. Flor, Nicole Uschold-Schmidt

Publikováno v: Cells, Vol 11, Iss 11, p 1817 (2022)

Chronic psychosocial stress participates prominently in the etiology of various psychiatric conditions and comorbid somatic pathologies; however, suitable pharmacotherapy of these disorders is still of high medical need. During the last few decades,

Externí odkaz: https://doaj.org/article/43dc228532f44c2fa901b720cdb1d1a7

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Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function. I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain

Autor: K, Walker, M, Bowes, M, Panesar, A, Davis, C, Gentry, A, Kesingland, F, Gasparini, W, Spooren, N, Stoehr, A, Pagano, P J, Flor, I, Vranesic, K, Lingenhoehl, E C, Johnson, M, Varney, L, Urban, R, Kuhn

Publikováno v: Neuropharmacology. 40(1)

The excitatory neurotransmitter, glutamate, is particularly important in the transmission of pain information in the nervous system through the activation of ionotropic and metabotropic glutamate receptors. A potent, subtype-selective antagonist of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dfff50a6dc69a60b0455381926bdc841
https://pubmed.ncbi.nlm.nih.gov/11077065

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SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5

Autor: M A, Varney, N D, Cosford, C, Jachec, S P, Rao, A, Sacaan, F F, Lin, L, Bleicher, E M, Santori, P J, Flor, H, Allgeier, F, Gasparini, R, Kuhn, S D, Hess, G, Veliçelebi, E C, Johnson

Publikováno v: The Journal of pharmacology and experimental therapeutics. 290(1)

Cell lines expressing the human metabotropic glutamate receptor subtype 5a (hmGluR5a) and hmGluR1b were used as targets in an automated high-throughput screening (HTS) system that measures changes in intracellular Ca2+ ([Ca2+]i) using fluorescence de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c002c0be01f0f425f0b69db729026b6d
https://pubmed.ncbi.nlm.nih.gov/10381773

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Akademický článek

Does whole body vibration exercise improve oxidative stress markers in women with fibromyalgia?

Autor: J.M. Santos, V.A. Mendonça, V.G.C. Ribeiro, R. Tossige-Gomes, S.F. Fonseca, A.C.N. Prates, J. Flor, A.C.C. Oliveira, J.B. Martins, B.C.C. Garcia, H.R. Leite, P.H.S. Figueiredo, M. Bernardo-Filho, A.C.R. Lacerda

Publikováno v: Brazilian Journal of Medical and Biological Research, Vol 52, Iss 8

The objective of this study was to investigate the effect of whole body vibration (WBV) exercise on oxidative stress markers in a group of women with fibromyalgia (FM) compared to a group of healthy women (CT). Twenty-one women diagnosed with FM and

Externí odkaz: https://doaj.org/article/e57d39a86a71487d827a2cdce079794a

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