Zobrazeno 1 - 10
of 18
pro vyhledávání: '"P J, Fenner"'
Autor:
Adam P. DeLuca, PhD, S. Scott Whitmore, PhD, Nicole J. Tatro, BSE, Jeaneen L. Andorf, BA, Ben P. Faga, BS, Laurel A. Faga, BS, Malia M. Colins, BA, Meagan A. Luse, BS, Beau J. Fenner, MD, PhD, Edwin M. Stone, MD, PhD, Todd E. Scheetz, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100397- (2023)
Purpose: Choroideremia is an X-linked choroidopathy caused by pathogenic variants in the CHM gene. It is characterized by the early appearance of multiple scotomas in the peripheral visual field that spread and coalesce, usually sparing central visio
Externí odkaz:
https://doaj.org/article/d0d6f23a7ef9472fabe9f324945bdab8
Autor:
Beau J. Fenner, Jonathan F. Russell, Arlene V. Drack, Alina V. Dumitrescu, Elliott H. Sohn, Stephen R. Russell, H. Culver Boldt, Louisa M. Affatigato, Jeremy M. Hoffmann, Jeaneen L. Andorf, Edwin M. Stone, Ian C. Han
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionX-linked retinoschisis (XLRS) is an inherited retinal disease (IRD) caused by pathogenic mutations in the retinoschisin gene, RS1. Affected individuals develop retinal layer separation, leading to loss of visual acuity (VA). Several XLRS
Externí odkaz:
https://doaj.org/article/76e26a92aacb4127a7bd34e7fd209fac
Publikováno v:
Diagnostics, Vol 13, Iss 23, p 3530 (2023)
(1) Purpose: ABCA4-associated retinal degeneration (ABCA4-RD) is a phenotypically diverse disease that often evades diagnosis, even by experienced retinal specialists. This may lead to inappropriate management, delayed genetic testing, or inaccurate
Externí odkaz:
https://doaj.org/article/aeedd530d43147da86b5649e27afb105
Autor:
Beau J. Fenner, Tien-En Tan, Amutha Veluchamy Barathi, Sai Bo Bo Tun, Sia Wey Yeo, Andrew S. H. Tsai, Shu Yen Lee, Chui Ming Gemmy Cheung, Choi Mun Chan, Jodhbir S. Mehta, Kelvin Y. C. Teo
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Inherited retinal diseases (IRDs) are a heterogenous group of orphan eye diseases that typically result from monogenic mutations and are considered attractive targets for gene-based therapeutics. Following the approval of an IRD gene replacement ther
Externí odkaz:
https://doaj.org/article/c4c8bad1c92a4de1a8bf19137a50ae8d
Autor:
Beau J. Fenner, Nur Zahirah B. M. Yusoff, Matthias Fuest, Lei Zhou, Francisco Bandeira, Howard Y. Cajucom-Uy, H. K. Tan, Jodhbir S. Mehta, Gary H. F. Yam
Publikováno v:
Eye and Vision, Vol 6, Iss 1, Pp 1-14 (2019)
Abstract Background Human corneal stromal keratocytes propagated in culture media supplemented with human amnion extract (AME) can correct early corneal haze in an animal model. Clinical application of cultivated keratocytes is limited by infectious
Externí odkaz:
https://doaj.org/article/75738034ce6e4282a6acf44db0839e08
Publikováno v:
Ophthalmology and Therapy, Vol 7, Iss 2, Pp 333-346 (2018)
Abstract Rising prevalence of diabetes worldwide has necessitated the implementation of population-based diabetic retinopathy (DR) screening programs that can perform retinal imaging and interpretation for extremely large patient cohorts in a rapid a
Externí odkaz:
https://doaj.org/article/07a18fc012454c1c9095440feb2daa23
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-12 (2017)
Abstract Background The regeneration of cofactors and the supply of alkane substrate are key considerations for the biocatalytic activation of hydrocarbons by cytochrome P450s. This study focused on the biotransformation of n-octane to 1-octanol usin
Externí odkaz:
https://doaj.org/article/5f62492ab6a3440ca6412bcbc6fae74c
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 15, Iss , Pp - (2019)
Purpose: To report a case of contact lens-related infectious keratitis caused by the Gram-negative plant pathogen Rhizobium radiobacter. Observations: A 26-year old lady with history of contact lens use presented with three weeks history of right eye
Externí odkaz:
https://doaj.org/article/28608f1905014a7d8812f84bdc4c0e34
Publikováno v:
Mires and Peat, Vol 14, Iss 05, Pp 1-19 (2014)
Peat humification analysis is presented as a robust palaeoclimatic proxy, suitable for use on mid–late Holocene peat sequences situated in the Southern Hemisphere. The proxy is shown to permit the identification of wet and dry shifts in a peat sequ
Externí odkaz:
https://doaj.org/article/3807a3f567af4c389612c27b2c793de9
Autor:
Guanghui Wu, Michaela J Day, Muriel T Mafura, Javier Nunez-Garcia, Jackie J Fenner, Meenaxi Sharma, Alieda van Essen-Zandbergen, Irene Rodríguez, Cindy Dierikx, Kristina Kadlec, Anne-Kathrin Schink, Marie Chattaway, John Wain, Reiner Helmuth, Beatriz Guerra, Stefan Schwarz, John Threlfall, Martin J Woodward, Neil Woodford, Nick Coldham, Dik Mevius
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75392 (2013)
The putative virulence and antimicrobial resistance gene contents of extended spectrum β-lactamase (ESBL)-positive E. coli (n=629) isolated between 2005 and 2009 from humans, animals and animal food products in Germany, The Netherlands and the UK we
Externí odkaz:
https://doaj.org/article/f24b234962e64a2d9b72d847e3bb38f2