Zobrazeno 1 - 10
of 11
pro vyhledávání: '"P J, Dunford"'
Autor:
Mark Bustoros, Shankara Anand, Romanos Sklavenitis-Pistofidis, Robert Redd, Eileen M. Boyle, Benny Zhitomirsky, Andrew J. Dunford, Yu-Tzu Tai, Selina J. Chavda, Cody Boehner, Carl Jannes Neuse, Mahshid Rahmat, Ankit Dutta, Tineke Casneuf, Raluca Verona, Efstathis Kastritis, Lorenzo Trippa, Chip Stewart, Brian A. Walker, Faith E. Davies, Meletios-Athanasios Dimopoulos, P. Leif Bergsagel, Kwee Yong, Gareth J. Morgan, François Aguet, Gad Getz, Irene M. Ghobrial
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Existing clinical models cannot fully capture smoldering multiple myeloma (SMM) heterogeneity. Here, integration of 42 genetic alterations from 214 SMM patients using an unsupervised binary matrix factorization clustering approach results in the iden
Externí odkaz:
https://doaj.org/article/078805a3b909435fb477a229095a08ed
Autor:
Kirsty Wienand, Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, David Wu, Jaegil Kim, Atanas Kamburov, Timothy R. Wood, Fathima Zumla Cader, Matthew D. Ducar, Aaron R. Thorner, Anwesha Nag, Alexander T. Heubeck, Michael J. Buonopane, Robert A. Redd, Kamil Bojarczuk, Lee N. Lawton, Philippe Armand, Scott J. Rodig, Jonathan R. Fromm, Gad Getz, Margaret A. Shipp
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 4065-4080 (2019)
Abstract: Classical Hodgkin lymphoma (cHL) is composed of rare malignant Hodgkin Reed-Sternberg (HRS) cells within an extensive, but ineffective, inflammatory/immune cell infiltrate. HRS cells exhibit near-universal somatic copy gains of chromosome 9
Externí odkaz:
https://doaj.org/article/fb5ce2af40844774bf1b968171dded99
Autor:
Carl L Manthey, Beverley A Moore, Yanqing Chen, Matthew J Loza, Xiang Yao, Hao Liu, Stanley M Belkowski, Holly Raymond-Parks, Paul J Dunford, Francisco Leon, Jennifer E Towne, Scott E Plevy
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0223918 (2019)
BACKGROUND & AIMS:Originally believed to be primarily a disorder of T-cell signaling, evidence shows that macrophage-lineage cells also contribute to the pathogenesis of Crohn's disease (CD). Colony stimulating factor-1 (CSF-1) is a key regulator of
Externí odkaz:
https://doaj.org/article/accefd4db87e43df909fc191a4931e30
Publikováno v:
International Journal of Multiphysics, Vol 5, Iss 2 (2016)
The present project is part of an effort towards the development of a ppb-level formaldehyde sensor system for indoor air quality. An electroceramic response model for a SnO2-NiO composite solid oxide sensing material of n-type conductivity inside th
Externí odkaz:
https://doaj.org/article/fb1a3ccc4efc42cba9b133b352fdd2d2
Autor:
R. L. Marr, P. J. Dunford
Publikováno v:
The Aeronautical Journal. 101:245-254
The Bell-Boeing V-22 Osprey tiltrotor is a unique aircraft capable of landing vertically, flying at speeds in excess of 300 KTAS (knots, true air speed), with the added feature of folding the rotor and wing for deployment from ships for US Navy, Mari
Autor:
B J R, Whittle, C, Varga, A, Berko, K, Horvath, A, Posa, J P, Riley, K A, Lundeen, A M, Fourie, P J, Dunford
Publikováno v:
British journal of pharmacology. 153(5)
Leukotriene B(4) (LTB(4)), formed by the sequential actions of the 5-lipoxygenase (5-LO) and leukotriene A(4) hydrolase (LTA(4)H), is a pro-inflammatory mediator implicated in the pathogenesis of inflammatory bowel disease. However, inhibitors of 5-L
Autor:
A M, Watkins, P J, Dunford, A M, Moffatt, P, Wong-Kai-In, M J, Holland, D S, Pole, G M, Thomas, J, Martin, N A, Roberts, M J, Mulqueen
Publikováno v:
Antiviral chemistrychemotherapy. 9(1)
Both herpes simplex virus type 1 (HSV-1) and HSV-2 encode a thymidine kinase enzyme which differs from cellular thymidine kinase in substrate specificity. Viral thymidine kinase enables the virus to replicate in cells that lack cellular thymidine kin
Autor:
Cheryl A. Grice, Kevin L. Tays, Brad M. Savall, Jianmei Wei, Christopher R. Butler, Frank U. Axe, Scott D. Bembenek, Anne M. Fourie, Paul J. Dunford, Katherine Lundeen, Fawn Coles, Xiaohua Xue, Jason P. Riley, Kacy N. Williams, Lars Karlsson, James P. Edwards
Publikováno v:
Journal of Medicinal Chemistry; Jun2008, Vol. 51 Issue 14, p4150-4169, 20p
Autor:
L, Thurmond Robin, J, Desai Pragnya, J, Dunford Paul, Wai-Ping, Fung-Leung, L, Hofstra Claudia, Wen, Jiang, Steven, Nguyen, P, Riley Jason, Siquan, Sun, N, Williams Kacy, P, Edwards James, Lars, Karlsson
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; April 2004, Vol. 309 Issue: 1 p404-13, 10p
Autor:
T. Leis, T. J. Nicholls, B. Anderson, M. Sharman, Maureen Barton, P. J. Dunford, A. Corbould, J. Elliott, G. M. Stephenson
Publikováno v:
Australian Veterinary Journal. 55:90-91