Zobrazeno 1 - 10
of 118
pro vyhledávání: '"P J, Donnelly"'
Autor:
Abdollah Jalilian, Galana Mamo Ayana, Temesgen Ashine, Elifaged Hailemeskel, Yehenew Asmamaw Ebstie, Eshetu Molla, Endashaw Esayas, Nigatu Negash, Abena Kochora, Muluken Assefa, Natnael Teferi, Daniel Teshome, Alison M. Reynolds, David Weetman, Anne L. Wilson, Birhanu Kenate, Martin J. Donnelly, Luigi Sedda, Endalamaw Gadisa
Publikováno v:
Infectious Diseases of Poverty, Vol 13, Iss 1, Pp 1-12 (2024)
Abstract Background Despite consecutive decades of success in reducing malaria transmission, Ethiopia went off track towards its goal of malaria elimination by 2030, as outlined in the NMCP malaria strategy. Recent malaria outbreaks in Ethiopia are a
Externí odkaz:
https://doaj.org/article/44ac0cb2407b4ce0b810aaae7bbcdc43
Autor:
Galana Mamo Ayana, Abdollah Jalilian, Temesgen Ashine, Eshetu Molla, Elifaged Hailemeskel, Dagmawi Hailu Yemane, Hailegiorgis Yirgu, Nigatu Negash, Natnael Teferi, Daniel Teshome, Alison M. Reynolds, David Weetman, Anne L. Wilson, Birhanu Kenate, Martin J. Donnelly, Luigi Sedda, Endalamaw Gadisa
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background Ethiopia faces several severe challenges in terms of malaria elimination, including drug resistance and diagnostic evasion in the Plasmodium falciparum parasite, insecticide resistance in the primary Anopheles malaria vector, and,
Externí odkaz:
https://doaj.org/article/f00dfdb0d20d45cabd5aea95fea868dd
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Alzheimer’s disease (AD) and more than twenty other dementias, termed tauopathies, are pathologically defined by insoluble aggregates of the microtubule-associated protein tau (MAPT). Although tau aggregation correlates with AD symptomolog
Externí odkaz:
https://doaj.org/article/63d6afaec5c74d609f4ee8baa1f19312
Autor:
Eric R Lucas, Sanjay C Nagi, Bilali Kabula, Bernard Batengana, William Kisinza, Alexander Egyir-Yawson, John Essandoh, Sam Dadzie, Joseph Chabi, Arjen E Van't Hof, Emily J Rippon, Dimitra Pipini, Nicholas J Harding, Naomi A Dyer, Chris S Clarkson, Alistair Miles, David Weetman, Martin J Donnelly
Publikováno v:
PLoS Biology, Vol 22, Iss 12, p e3002898 (2024)
To keep ahead of the evolution of resistance to insecticides in mosquitoes, national malaria control programmes must make use of a range of insecticides, both old and new, while monitoring resistance mechanisms. The outdoor-biting malaria vector Anop
Externí odkaz:
https://doaj.org/article/c78e3685cb4044f186d5814f74a0d0b0
Autor:
Amy Lynd, Samuel Gonahasa, Sarah G. Staedke, Ambrose Oruni, Catherine Maiteki-Sebuguzi, Penelope A. Hancock, Erin Knight, Grant Dorsey, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Janet Hemingway, Moses R. Kamya, Daniel McDermott, Eric R. Lucas, Martin J. Donnelly
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pyrethroid bednets treated with the synergist piperonyl butoxide (PBO) offer the possibility of improved vector control in mosquito populations with metabolic resistance. In 2017–2019, we conducted a large-scale, cluster-randomised trial (
Externí odkaz:
https://doaj.org/article/bfc7826f3d024a8f813aed9eb41abdc3
Autor:
Jaffer Okiring, Samuel Gonahasa, Catherine Maiteki-Sebuguzi, Agaba Katureebe, Irene Bagala, Peter Mutungi, Simon P. Kigozi, Jane F. Namuganga, Joaniter I. Nankabirwa, Moses R. Kamya, Martin J. Donnelly, Thomas S. Churcher, Sarah G. Staedke, Ellie Sherrard-Smith
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Disruptions in malaria control due to COVID-19 mitigation measures were predicted to increase malaria morbidity and mortality in Africa substantially. In Uganda, long-lasting insecticidal nets (LLINs) are distributed nationwide ev
Externí odkaz:
https://doaj.org/article/d3636a4a662f45899ed5d3a1c2468cc6
Autor:
Jackline Kosgei, John E. Gimnig, Vincent Moshi, Seline Omondi, Daniel P. McDermott, Martin J. Donnelly, Collins Ouma, Bernard Abong’o, Eric Ochomo
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Vector surveillance is among the World Health Organization global vector control response (2017–2030) pillars. Human landing catches are a gold standard but difficult to implement and potentially expose collectors to malaria inf
Externí odkaz:
https://doaj.org/article/5f69cd07c896458a90ed7087f334d0b0
Autor:
Jessy D. Martinez, Lydia G. Wilson, William P. Brancaleone, Kathryn G. Peterson, Donald S. Popke, Valentina Caicedo Garzon, Roxanne E. Perez Tremble, Marcus J. Donnelly, Stephany L. Mendez Ortega, Daniel Torres, James J. Shaver, Sha Jiang, Zhongying Yang, Sara J. Aton
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114266- (2024)
Summary: Fragile X syndrome (FXS) is associated with disrupted cognition and sleep abnormalities. Sleep loss negatively impacts cognitive function, and one untested possibility is that disrupted cognition in FXS is exacerbated by abnormal sleep. We t
Externí odkaz:
https://doaj.org/article/844290dcb3014c1d90d0fca91935229f
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
The major malaria mosquitoes, Anopheles gambiae s.l and Anopheles funestus, are some of the most studied organisms in medical research and also some of the most genetically diverse. When designing polymerase chain reaction (PCR) or hybridisation-base
Externí odkaz:
https://doaj.org/article/8a44ef50065b4699b52fb19b80d2fc75
Autor:
Arjen E. van’t Hof, Amy Lynd, Ambrose Oruni, Ismail Onyige, Harun Njoroge, Enock Matovu, Martin J. Donnelly
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background The effectiveness of long-lasting insecticidal nets (LLINs) are being threatened by growing resistance to pyrethroids. To restore their efficacy, a synergist, piperonyl butoxide (PBO) which inhibits cytochrome P450s has been incorporated i
Externí odkaz:
https://doaj.org/article/52d9dbac34cd475baa3465e5ca181bcc