Zobrazeno 1 - 10
of 17
pro vyhledávání: '"P J, Crossman"'
Autor:
Kerstin H. Mair, Assiatu J. Crossman, Bettina Wagner, Susanna Babasyan, Leela Noronha, Patricia Boyd, Dante Zarlenga, Maria Stadler, Katinka A. van Dongen, Wilhelm Gerner, Armin Saalmüller, Joan K. Lunney
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells have been studied extensively in humans and mice for their vital role in the vertebrate innate immune system. They are known to rapidly eliminate tumors or virus infected cells in an immune response utilizing their lytic pro
Externí odkaz:
https://doaj.org/article/33c01f50dd4f46d682191de566333d6c
Autor:
Yufeng Hou, Jizhong Bai, Xin Shen, Oscar de Langen, Amy Li, Sean Lal, Cristobal G. dos Remedios, David Baddeley, Peter N. Ruygrok, Christian Soeller, David J. Crossman
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The disrupted organisation of the ryanodine receptors (RyR) and junctophilin (JPH) is thought to underpin the transverse tubule (t-tubule) remodelling in a failing heart. Here, we assessed the nanoscale organisation of these two key proteins in the f
Externí odkaz:
https://doaj.org/article/b2bbfa1206e548a38c1020f6a2d5211e
Autor:
Izzy Jayasinghe, Alexander H. Clowsley, Oscar de Langen, Sonali S. Sali, David J. Crossman, Christian Soeller
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Remodelling of the membranes and protein clustering patterns during the pathogenesis of cardiomyopathies has renewed the interest in spatial visualisation of these structures in cardiomyocytes. Coincidental emergence of single molecule (super-resolut
Externí odkaz:
https://doaj.org/article/9ec4d5a1c6c044c5b36200a68ee41172
Autor:
Claire L. Curl, Vennetia R. Danes, James R. Bell, Antonia J. A. Raaijmakers, Wendy T. K. Ip, Chanchal Chandramouli, Tristan W. Harding, Enzo R. Porrello, Jeffrey R. Erickson, Fadi J. Charchar, Andrew R. Kompa, Amanda J. Edgley, David J. Crossman, Christian Soeller, Kimberley M. Mellor, Jonathan M. Kalman, Stephen B. Harrap, Lea M. D. Delbridge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundAmong the growing numbers of patients with heart failure, up to one half have heart failure with preserved ejection fraction (HFpEF). The lack of effective treatments for HFpEF is a substantial and escalating unmet clinical need—and the l
Externí odkaz:
https://doaj.org/article/1d494628ead14a7dbee011a799b45a35
Autor:
Isuru D. Jayasinghe, Alexander H. Clowsley, Michelle Munro, Yufeng Hou, David J. Crossman, Christian Soeller
Publikováno v:
European Journal of Translational Myology, Vol 25, Iss 1, Pp 15-26 (2014)
The t-tubular system plays a central role in the synchronisation of calcium signalling and excitation-contraction coupling in most striated muscle cells. Light microscopy has been used for imaging t-tubules for well over 100 years and together with e
Externí odkaz:
https://doaj.org/article/e43a056b2475454bab1a8a71471ea98a
Autor:
J. Crossman, M. N. Futter, P. G. Whitehead, E. Stainsby, H. M. Baulch, L. Jin, S. K. Oni, R. L. Wilby, P. J. Dillon
Publikováno v:
Hydrology and Earth System Sciences, Vol 18, Iss 12, Pp 5125-5148 (2014)
Hydrological processes determine the transport of nutrients and passage of diffuse pollution. Consequently, catchments are likely to exhibit individual hydrochemical responses (sensitivities) to climate change, which are expected to alter the timing
Externí odkaz:
https://doaj.org/article/6e5f9282fc7a4729bbe4420e8fba0bb3
Autor:
Vijay Rajagopal, Gregory Bass, Cameron G Walker, David J Crossman, Amorita Petzer, Anthony Hickey, Ivo Siekmann, Masahiko Hoshijima, Mark H Ellisman, Edmund J Crampin, Christian Soeller
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 9, p e1004417 (2015)
Spatio-temporal dynamics of intracellular calcium, [Ca2+]i, regulate the contractile function of cardiac muscle cells. Measuring [Ca2+]i flux is central to the study of mechanisms that underlie both normal cardiac function and calcium-dependent etiol
Externí odkaz:
https://doaj.org/article/ef0aa2a9574e4d2a936460542810080d
Publikováno v:
PLoS ONE, Vol 6, Iss 4 (2011)
Externí odkaz:
https://doaj.org/article/232fb02bcb6340a3b99398230619d8c5
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17901 (2011)
BACKGROUND: The cardiac myocyte t-tubular system ensures rapid, uniform cell activation and several experimental lines of evidence suggest changes in the t-tubular system and associated excitation-contraction coupling proteins may occur in heart fail
Externí odkaz:
https://doaj.org/article/7f10de691cc84511bfbec4125b9b53be
Publikováno v:
Veterinary Record. 95:539-560
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b500809bc9b8df21d57b5e8701abb39b
https://doi.org/10.1136/vr.95.23.539
https://doi.org/10.1136/vr.95.23.539